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preclinical studies

A Tumor-mimic Model for Evaluating the Accuracy of HIFU Preclinical Studies: An In Vivo Study.

A Tumor-mimic Model for Evaluating the Accuracy of HIFU Preclinical Studies: An In Vivo Study.

... HIFU Preclinical Studies: An In Vivo Study ...Three studies were carried out: (i) in vitro experiments were conducted to study the acoustical proprieties of the tumor mimics; (ii) in vivo experiments ...

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Pomegranate seed oil for nutritional management of postmenopausal osteoporosis: in vitro and preclinical studies

Pomegranate seed oil for nutritional management of postmenopausal osteoporosis: in vitro and preclinical studies

... and preclinical studies Mélanie Spilmont 1,2,3,6 , Laurent Léotoing 1,2,3 , Marie-Jeanne Davicco 1,2,3 , Patrice Lebecque 1,2,3 , Sylvie Mercier 1,2,3 , Elisabeth Miot-Noirault 4,5 , Laurent Rios 6 , Yohann ...

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en fr Clinical and preclinical studies of the early phase of Alzheimer's disease Etude préclinique et clinique de la phase précoce de la maladie d'Alzheimer

... "Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study." Lancet Neurol 53: 228-234... "The amyloid hypothesis[r] ...

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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

... Atoh1 (or Math1) is a proneural basic helix-loop-helix (bHLH) transcription factor highly expressed in GNP cells of the cerebellum [ 90 ]. Atoh1 is a key factor in cerebellar development, acting downstream of Shh sig- ...

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en fr Characterization and Molecular Imaging and Atherosclerotic Plaque : Preclinical Studies Caractérisation et imagerie moléculaire de la plaque d'athérome : études pré-cliniques

... dans du sang humain a montré des résultats analogues à ceux obtenus par l’étude in vitro réalisée dans le sang de souris, tant en termes de stabilité dans la fraction libre du plasma qu'[r] ...

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en fr Interest of 5-HT4 receptors in Alzheimer’s disease : behavioral and electrophysiological preclinical studies on mice Intérêts des récepteurs 5-HT4 dans la pathologie Alzmeimer : étude préclinique comportementale et électrophysiologie sur tranche d'hippocampe de souris

... 181 Tableau 6: Effets de la stimulation des récepteurs 5-HT4 par l’agoniste RS67333 sur la transmission de base et sur la plasticité synaptique, comparaison entre les souris C57/BL6 [r] ...

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Small Animal Shanoir (SAS) A Cloud-Based Solution for Managing Preclinical MR Brain Imaging Studies

Small Animal Shanoir (SAS) A Cloud-Based Solution for Managing Preclinical MR Brain Imaging Studies

... With SAS, we show that animal population imaging is feasible and that research in this field can be conducted using tools compatible with open sharing and use of automated workflow tools to ensure accessibility and ...

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Analysis of machine perfusion benefits in kidney grafts: a preclinical study

Analysis of machine perfusion benefits in kidney grafts: a preclinical study

... for preclinical studies as it is close to humans, par- ticularly in regards to the multipapillar multilobular orga- nization of its kidney, only found in higher mammals, implying a complex vascular bed ...

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A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI

A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI

... spectra. Preclinical studies impose additional limitations on RF-coil ...of preclinical scanners, where RF-coils must operate inside an electrically narrow, shielded ...mid-range preclinical ...

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Preclinical Alzheimer's disease: a systematic review of the cohorts underlying the concept

Preclinical Alzheimer's disease: a systematic review of the cohorts underlying the concept

... studying preclinical early onset forms of AD as these mutations have a 100% penetrance so that all carriers will develop the ...sectional studies have been performed in these asymptomatic carriers to ...

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Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning

Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning

... in preclinical cerebral ischemia ...of studies and trials may actually dissuade increased engagement, in an era of declining resources in this ...the preclinical level for ...

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Physicochemical characterization and biocompatibility studies of persistent luminescence nanoparticles for preclinical diagnosis applications

Physicochemical characterization and biocompatibility studies of persistent luminescence nanoparticles for preclinical diagnosis applications

... involves the use of polyethylene glycol (PEG) coatings to limit these nonspecific interactions [44, 64, 240]. Various analytical methodologies have been reported in the literature to study NP/protein interactions, i.e. ...

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A Novel Telemanipulated Robotic Assistant for Surgical Endoscopy: Preclinical Application to ESD

A Novel Telemanipulated Robotic Assistant for Surgical Endoscopy: Preclinical Application to ESD

... ViaCath, initially developed by Endovia was brought to the level of preclinical trials [16]. It provided highly articulated flexible instruments (6 DoFs per instrument) by using two consecutive two DoFs bending ...

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A Multicenter Preclinical MRI Study: Definition of Rat Brain Relaxometry Reference Maps

A Multicenter Preclinical MRI Study: Definition of Rat Brain Relaxometry Reference Maps

... FIGURE 4 | Relaxation values for this study and five published studies (see References list for details) in 29 regions of interest. Left: T1 relaxation values. Scale: 500 ms/division. Right: T2 relaxation. Scale: ...

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Cardiovascular System Studies

Cardiovascular System Studies

... The present phase of this work has been completed and the results have been pre- sented as theses to the Department of Electrical Engineering, M. Hinde, A Sensor[r] ...

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Cardiovascular System Studies

Cardiovascular System Studies

... Our research is concerned mainly with the quantitative description and mathematical simulation of the biological control system involved with the regulation of blood [r] ...

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Latent class analysis identifies functional decline with Amsterdam IADL in preclinical Alzheimer's disease

Latent class analysis identifies functional decline with Amsterdam IADL in preclinical Alzheimer's disease

... evidenced in AD [29] , which can in turn have an impact on IADLs such as driving. Moreover, sociocultural issues may also have a role, due to the historically gendered divi- sion of household labor, especially for ...

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Preclinical longitudinal imaging of tumor microvascular radiobiological response with functional optical coherence tomography

Preclinical longitudinal imaging of tumor microvascular radiobiological response with functional optical coherence tomography

... literature studies of radiobiological microvascu- lar responses oten report conlicting results, likely due to the variations in experimental protocols (animal and tumor models, irradiation methods, ...

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Comparisons in Migration Studies

Comparisons in Migration Studies

... migration studies (Mahler and Pessar, ...migration studies, which have precisely given a new visibility to women in migration ...comparative studies, examining and comparing systematically men and ...

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Consolidated report on case studies

Consolidated report on case studies

... 3.2.1 Large scale environmental monitoring In Ireland, large scale assessment studies have been carried out by the Ministry of Agriculture with experts. The measures implemented had a measured impact on the ...

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