platelet aggregation
Projected inhibition of platelet aggregation with ticagrelor twice daily vs. clopidogrel once daily based on patient adherence data (the TWICE project)
... Introduction Vascular damage such as rupture or erosion of an atherosclerotic plaque can trigger platelet aggregation. The resultant thrombus may lead to vascular occlusion, causing hypoxia and tissue ...
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Antiplatelet Agents Have a Distinct Efficacy on Platelet Aggregation Induced by Infectious Bacteria
... (LTA) Platelet aggregation was analyzed by a turbidimetric method with a lumi-Aggregometer (APACT-4004, Elitech, France) ( Chia et ...100% aggregation ” and PRP was used to adjust the ...of ...
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Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.: Role of myosin IIA in hemostasis and thrombosis
... weak platelet stimulation, is in fact dispensable for platelet secretion when increasing agonist ...on platelet aggregation and secretion, was the alteration in thrombus formation both in ...
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ATP Augments von Willebrand Factor-dependent Shear-induced Platelet Aggregation through Ca2+-Calmodulin and Myosin Light Chain Kinase Activation
... and Marc F. Hoylaerts‡储 From the ‡Center for Molecular and Vascular Biology and the ¶ Laboratory of Morphology and Molecular Pathology, University of Leuven, 3000 Leuven, Belgium Shear stress triggers von Willebrand ...
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A serotonin-induced N-glycan switch regulates platelet aggregation.
... the aggregation responses between platelets isolated from WT mice after 24 hours of infusion with saline (SAL) or ...promote platelet aggregation by different ...Collagen-induced platelet ...
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Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation.
... Our study aimed to establish the complete structure of the main dihydroxy conjugated triene issued from the lipoxygenation (soybean enzyme) of docosahexaenoic acid (DHA), named PDX,[r] ...
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Effects of a trans isomer of arachidonic acid on rat platelet aggregation and eicosanoid production
... Tram n-3 eicosapentaenoic and docosa- hexaenoic acid isomers exhibit different inhibitory effects on arachidonic acid metabolism in human platelets com- pared to the respective ci[r] ...
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Platelet Functions During Extracorporeal Membrane Oxygenation. Platelet-Leukocyte Aggregates Analyzed by Flow Cytometry as a Promising Tool to Monitor Platelet Activation
... of platelet surface receptors with thrombocytopenia and AVWS could contribute to bleeding events in this situation of elevated shear ...and platelet dysfunction. Concerning platelet ...
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CD40 signalling in platelet function
... aggravated platelet and coagulation cascade ...inhibit platelet activation (PGI 2 , NO, NTPDase-1) and thrombin generation (thrombomodulin), plaque rupture in combination with a severe pre-existing arterial ...
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Platelet function in aging
... AND PLATELET HYPERREACTIVITY The human and animal aging process is accompanied by an increase in oxidative stress ( 38 – 40 ...in platelet activation by acting as a second messenger or by producing oxidized ...
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Ca2+ influx via the platelet P2X1 ion channel contributes to collagen-induced platelet activation.
... in platelet activation, angiogenesis 7 and inflam- matory ...of platelet activation and also exhibit prolonged bleeding times with resistance to systemic throm- boembolism (d'Apice et ...decreased ...
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Dabigatran enhances platelet reactivity and platelet thrombin receptor expression in patients with atrial fibrillation: comment
... study, platelet reactivity and thrombin receptor expression were measured in 13 patients before and after planned initiation of dabigatran ...(TRAP)-induced platelet aggregation by enhancing thrombin ...
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The platelet ATP and ADP receptors.
... 63]. The intronless genes for P2Y 1 and P2Y 12 receptors are co-localized on chromosome 3q21-q25 [64] and share 22% sequence identity [27, 62]. P2Y 12 is the therapeutic target of ticlopidine and clopidogrel, two ...
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Increased platelet reactivity and platelet–leukocyte aggregation after elective coronary bypass surgery
... Only patients with stable coronary artery disease who underwent elective CABG were included in this study as patients treated for acute coronary syndromes require dual antiplatelet treatment after the operation [ 23 ]. ...
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Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors.
... had platelet counts between 60 and 125 x 10 9 /L (Table ...revealed platelet anisocytosis (data not shown), as confirmed by EM (Figure 1E), which further highlighted the presence of occasional hypogranular ...
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Graph Aggregation (Extended Abstract)
... graph aggregation in general abstract terms and demonstrated its relevance to a wide range of ...of aggregation and it allows us to ask questions regarding the existence of methods that meet a certain set ...
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Strategy-proof preference aggregation
... in aggregation rules (also called social welfare functions) that map profiles of individual preferences into social orderings of the ...several aggregation rules can be recommended on the basis of various ...
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Aggregation of Heterogeneous Beliefs
... The main purpose of Calvet et al. (2002) is to incorporate in the represen- tation of the economy some degree of heterogeneity in the investors beliefs and to analyze how one could extend and modify the traditional ...
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Aggregation of Multiple Knockoffs
... Unfortunately, KO has a major drawback, related to the random nature of the knockoff variables: two different draws yield two different solutions, leading to large, uncontrolled fluctuations in power and false discovery ...
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Introduction to Judgment Aggregation
... Three operators (sceptical, credulous and super credulous) are defined and investigated in [ 6 ], as well as their properties. It is shown that, by iterating the aggregation process, not only a collective ...
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