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PET imaging

Positron range in PET imaging: an alternative approach for assessing and correcting the blurring

Positron range in PET imaging: an alternative approach for assessing and correcting the blurring

... Submitted to: Physics in Medicine and Biology 1. Introduction Because of the improving spatial resolution of the physical detectors, the distance from positron emission to positron annihilation (positron range) is ...

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[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

... resonance imaging (MRI). The authors confirmed the value of PET imaging with [ 18 F]ML-10 for early assessment of tumor response to therapy as well as the potential of this radiotracer to visualize ...

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Clinical utility of amyloid PET imaging in the differential diagnosis of atypical dementias and its impact on caregivers

Clinical utility of amyloid PET imaging in the differential diagnosis of atypical dementias and its impact on caregivers

... amyloid PET imaging in the differential diagnosis of early-onset atypical cases of ...Amyloid PET was associated with a diagnostic change in 9/28 cases ...amyloid PET in atypical cases with an ...

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Optimization of brain PET imaging for a multicentre trial: the French CATI experience

Optimization of brain PET imaging for a multicentre trial: the French CATI experience

... forward-thinking, imaging-based multicentre clinical trial that in- volved 50 centres in North America, with the aim of identifying biomarkers of ...the PET imaging carried out in this study, the ...

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Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain

Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain

... hydrolysing the second messengers cyclic adenosine monophosphate (cAMP) and/or cyclic guanosine monophosphate (cGMP) throughout the body and brain. Altered cyclic nucleotide- mediated signalling has been associated with ...

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Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy

Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy

... For in vivo PET imaging, whole-body scans were acquired using a small-animal device (eXplore Vista, GE Healthcare). Acquisition (30 minutes duration, 2 bed positions) was performed with a 250 to 700 keV ...

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Automated radiosynthesis of 1-(2-[18F]fluoroethyl)-tryptophan, a potential substrate for indoleamine 2,3-dioxygenase PET imaging

Automated radiosynthesis of 1-(2-[18F]fluoroethyl)-tryptophan, a potential substrate for indoleamine 2,3-dioxygenase PET imaging

... [6] Dolušić E.; Frédérick R.; & al. (2011) Eur. J. Med. Chem., 46, 3058-3065. [7] Dolušić E.; Frédérick R.; & al. (2011) J. Med. Chem., 54, 5320-5334. Automated radiosynthesis of 1-(2-[ 18 F]fluoroethyl)- ...

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Development of New Radiotracers for PET Imaging of Adrenomedullin and Angiotensin II Type 1 Receptors

Development of New Radiotracers for PET Imaging of Adrenomedullin and Angiotensin II Type 1 Receptors

... a PET camera, when opposing 511 keV gamma rays reach simultaneously two detector crystals, a flash of light (scintillation) is produced and due to the photoelectric effect, released electrons then magnified their ...

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Calculating an estimate of tissue integrated activity in 18F-FDG PET imaging using one SUV value.

Calculating an estimate of tissue integrated activity in 18F-FDG PET imaging using one SUV value.

... based’ dosimetric approaches are usually considered as sufficient to deduce a first order estimate of irradiation induced by the nuclear medicine procedure [6]. How- ever, even in current clinical 18 F-FDG PET ...

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The cell labeling efficacy, cytotoxicity and relaxivity of copper-activated MRI/PET imaging contrast agents

The cell labeling efficacy, cytotoxicity and relaxivity of copper-activated MRI/PET imaging contrast agents

... single imaging modality among all the existing imaging ...different imaging techniques by combining two or more imaging modalities while eliminating or reducing their ...multimodal ...

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Detection of bladder metabolic artifacts in (18)F-FDG PET imaging.

Detection of bladder metabolic artifacts in (18)F-FDG PET imaging.

... a priori spatial information. The k-means algorithm was used to ensure an unsupervised clustering and low com- putational cost. As bladder uptake is not systematically found in these procedures, our detection method ...

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Automatic Classification of FDG-PET imaging data in Disorders of Consciousness

Automatic Classification of FDG-PET imaging data in Disorders of Consciousness

... FDG-PET imaging data in Disorders of Consciousness Medial and lateral frontoparietal cortices and brain stem appear to play a key role in consciousness state, as shown from the weights assigned by the ...

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Radiolabeled Bombesin Analogs to Improve Prostate Cancer Diagnosis by PET Imaging

Radiolabeled Bombesin Analogs to Improve Prostate Cancer Diagnosis by PET Imaging

... MAGING PET technique shows a promising future in the imaging of prostate cancer (Hong et ...2010). PET imaging requires radionuclides that emit positron (β + ...the PET scanner, a ring ...

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A pretargeting system for tumor PET imaging and radioimmunotherapy

A pretargeting system for tumor PET imaging and radioimmunotherapy

... To further advance the clinical applications of pretarget- ing, it also became clear that humanized recombinant bispecific antibodies must be produced. Although many different for- mats of bispecific antibodies had been ...

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Staging of regional nodes in AJCC stage I and II melanoma: 18FDG PET imaging versus sentinel node detection.

Staging of regional nodes in AJCC stage I and II melanoma: 18FDG PET imaging versus sentinel node detection.

... = 1.89 mm) scheduled for a LM/SL underwent 18 FDG PET imaging in pretreatment staging. All patients included into this institutional protocol were classified at stage I or II cutaneous melanoma (T1-4 N0 M0) ...

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PROGNOSTIC VALUE OF POSTTREATMENT FEDG-PET IMAGING FOLLOWING COMBINED CHEMORADIATION THERAPY IN LOCALLY ADVANCED CERVICAL CANCER

PROGNOSTIC VALUE OF POSTTREATMENT FEDG-PET IMAGING FOLLOWING COMBINED CHEMORADIATION THERAPY IN LOCALLY ADVANCED CERVICAL CANCER

... Conclusions In patients treated with CT/RT for locally advanced cervical cancer, despite limited performances to predict cervical residual disease, posttreatment FEDG-PET is predictive of patients’ prognosis and ...

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Longitudinal mouse-PET imaging: a reliable method for estimating binding parameters without a reference region or blood sampling

Longitudinal mouse-PET imaging: a reliable method for estimating binding parameters without a reference region or blood sampling

... The correlations between the parameters from the PET scans and the autoradiography are shown in Fig. 4 . For each time point, and over all animals at all time points, there is an increase in the correlation ...

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Impact of respiratory motion correction on the detection of small lesions in whole-body PET imaging: A simulation study

Impact of respiratory motion correction on the detection of small lesions in whole-body PET imaging: A simulation study

... of PET measurements, as shown in numerous ...reconstructed PET images, while the second method integrates the motion fields during the iterative reconstruction ...

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Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis

Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis

... Neurobiol. 9:207–227. Johnson, E.W., de Lanerolle, N.C., Kim, J.H., Sundaresan, S., Spencer, D.D., Mattson, R.H., Zoghbi, S.S., Baldwin, R.M., Hoffer, P.B., and Seibyl, J.P. (1992). “Central” and “peripheral” ...

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View of Understanding Positron Emission Tomography (PET) Imaging

View of Understanding Positron Emission Tomography (PET) Imaging

... 4. Tournier N, Goutal S, Auvity S, Traxl A, Mairinger S, Wanek T, Helal OB, Buvat I, Soussan M, Caillé F, Langer O, (2017) Strate- gies to inhibit ABCB1- and ABCG2-mediated efflux transport of erlotinib at the ...

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