• Aucun résultat trouvé

oxidative damage

Preventive effects of an original combination of grape seed polyphenols with amine fluoride on dental biofilm formation and oxidative damage by oral bacteria

Preventive effects of an original combination of grape seed polyphenols with amine fluoride on dental biofilm formation and oxidative damage by oral bacteria

... its effectiveness on the biofilm formation. GSE presented a high Trolox equivalent antioxidant capacity (TEAC) value, proving its capacity to scavenge free radicals. To improve these first results, we investigated in ...

13

New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells

New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells

... 2 Institute for Neurosciences of Montpellier, INSERM U1051-UM, Hospital St Eloi, 80 rue Augustin Fliche, 34091 Montpellier, France; philippe.brabet@inserm.fr (P.B.); laurent.guillou@inserm.fr (L.G.) * Correspondence: ...

19

Preventive effects of an original combination of grape seed polyphenols with amine fluoride on dental biofilm formation and oxidative damage by oral bacteria

Preventive effects of an original combination of grape seed polyphenols with amine fluoride on dental biofilm formation and oxidative damage by oral bacteria

... To improve these first results, we investigated in this study the combination of GSE with an amine fluoride (Fluorinol ! , Pierre Fabre Laboratories, Castres, France), known for its protective properties on the ...

12

Quercetin potentiates insulin secretion and protects INS-1 pancreatic b-cells against oxidative damage via the ERK1/2 pathway

Quercetin potentiates insulin secretion and protects INS-1 pancreatic b-cells against oxidative damage via the ERK1/2 pathway

... In summary, the present study allowed us to show that quercetin, but not the two other anti- oxidants (resveratrol or NAC), potentiated glucose- induced insulin secretion and protected b-cell function and viability ...

17

Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA

Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA

... activation 6 ; (ii) perturbations of the epigenetic landscape and the transcriptome 7,8 ; and (iii) an elevated oxidative stress degrading cellular components. 9 In this study, we injected dystrophic mdx4Cv mice ...

10

Oxidative proteome alterations during skeletal muscle ageing

Oxidative proteome alterations during skeletal muscle ageing

... [2 , 13 , 20] . The identi fication of such oxidatively modified proteins (i.e. the oxi-proteome components), can give some insights into the mechanisms by which these damaged proteins accumulate and potentially affect ...

9

Oxidative Stress in Cardiovascular Diseases

Oxidative Stress in Cardiovascular Diseases

... of oxidative damage. Indeed, oxidative stress is an important factor involved in cardiovascular diseases ...of oxidative stress in cardiovascular diseases and we will focus on ROS produced by ...

16

Tissue damage from neutrophil-induced oxidative stress in COVID-19

Tissue damage from neutrophil-induced oxidative stress in COVID-19

... [3]. Oxidative stress is the result of an imbalance between oxidant production and antioxidant mechanisms that leads to oxidative damage, including lipid peroxidation and DNA oxidation ...and ...

4

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa

... The HPLC system consisted of a pump M 2200 (Bischoff, Leonberg, Germany) and an autosampler 738 (ICS, Toulouse, France) equipped with a 12:5 £ 4:6 mm Spherisorb ODS 2 column (Bischoff). A detector focus (Spectra-Physics, ...

7

Osmoregulation and salinity-induced oxidative stress: is oxidative adaptation determined by gill function?

Osmoregulation and salinity-induced oxidative stress: is oxidative adaptation determined by gill function?

... cell damage levels in posterior gills remain unchanged, allowing us to hypothesize that the induction of antioxidant enzymes (notably SOD) may occur before the dSW- derived ROS formation overwhelms the basal ...

11

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2'-deoxyguanosine, in rat colonic mucosa.

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2'-deoxyguanosine, in rat colonic mucosa.

... The HPLC system consisted of a pump M 2200 (Bischoff, Leonberg, Germany) and an autosampler 738 (ICS, Toulouse, France) equipped with a 12:5 £ 4:6 mm Spherisorb ODS 2 column (Bischoff). A detector focus (Spectra-Physics, ...

7

Antibiotics-induced oxidative stress

Antibiotics-induced oxidative stress

... 5. Conclusions and future directions ATBs with different chemical structures can cause adverse side effects in various human tissues and cells, especially the liver. ATBs frequently cause cholestasis which most often is ...

17

Nuclear Integrity but Not Topology of Mouse Sperm Chromosome is Affected by Oxidative DNA Damage

Nuclear Integrity but Not Topology of Mouse Sperm Chromosome is Affected by Oxidative DNA Damage

... treatment condition; ‘ b ’ represents p < 0.001 for WT NaOH condition; ‘ c ’ represents p < 0.001 for WT DTT condition; ‘ d ’ represents p < 0.001 for no treatment/genotype condition. 3. Discussion In recent ...

17

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis

... which oxidative stress may play a major pathophysiological ...of oxidative and antioxidative stress markers in chronic glaucoma compared with a control ...reporting oxidative and antioxidative stress ...

20

The transcription-coupled DNA repair-initiating protein CSB promotes XRCC1 recruitment to oxidative DNA damage

The transcription-coupled DNA repair-initiating protein CSB promotes XRCC1 recruitment to oxidative DNA damage

... local oxidative damage in CSB-deficient cells ( 22 ...induced oxidative dam- age in both wt and CSB-deficient cells (Figure 1 C), sug- gesting that a fraction of OGG1 is immobilized (bound) at these ...

11

Hyperelasticity with volumetric damage

Hyperelasticity with volumetric damage

... can be called a volumetric damage. In the general framework of large strain, the material is sup- posed homogeneous, isotropic and hyperelastic. Moreover, we assume that it initially contains small flaws that can ...

7

p53-PGC-1α Pathway Mediates Oxidative Mitochondrial Damage and Cardiomyocyte Necrosis Induced by Monoamine Oxidase-A Upregulation: Role in Chronic Left Ventricular Dysfunction in Mice

p53-PGC-1α Pathway Mediates Oxidative Mitochondrial Damage and Cardiomyocyte Necrosis Induced by Monoamine Oxidase-A Upregulation: Role in Chronic Left Ventricular Dysfunction in Mice

... Upregulation of MAO-A sensitizes cardiomyocytes to necrosis through p53 activation. To gain insight into the mechanism involved in MAO-A-dependent cell necrosis, we developed an in vitro model of MAO-A adenoviral vector ...

49

Dynamic damage in metal: porosity as a test for damage models

Dynamic damage in metal: porosity as a test for damage models

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

5

Strain-gradient vs damage-gradient regularizations of softening damage models

Strain-gradient vs damage-gradient regularizations of softening damage models

... 2. The second family (SG0) contains the functions G that vanish at α = 1 and hence that lead to a loss of any stiffness at α = 1, the material being unable to sustain any stress. This family will be studied in the next ...

31

Blasting and building damage

Blasting and building damage

... The most common displacement-measuring instrument is the portable seismograph, which contains in one package three pendulum elements (for three components of vibration) together with optical and recording apparatus. The ...

7

Show all 1152 documents...

Sujets connexes