nude mice
Stromelysin-3 expression promotes tumor take in nude mice
... Tumors that are obtained by S.C. injection of malignant cells into nude mice should be regarded as a model for meta- static implantation rather than for primary tumor development (45). Indeed, S.C. injected ...
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Determining a Clinically Relevant Strategy for Bone Tissue Engineering: An ''All-in-One'' Study in Nude Mice
... Histomorphometric and SEM assessment The MSC-, BG-, and TBM-loaded ceramics were implanted subcutaneously in nude mice, and revealed inconsistent osteogenic results after eight weeks. Histological ...
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Role of endocrine status and cell type in adhesion of human endometrial cells to the peritoneum in nude mice
... that nude mice are convenient recipients to study early implantation ...neoangiogenesis. Nude mice are suitable recipients for human tissue transplantation because they lack the defensive ...
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Synergistic effect of cisplatin and synchrotron irradiation on F98 gliomas growing in nude mice.
... Among brain tumors, glioblastoma multiforme appears as one of the most aggressive forms of cancer with poor prognosis and no curative treatment available. Recently, a new kind of radio-chemotherapy has been developed ...
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Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice
... A total of 40,000 SVF cells/cm 2 were plated and grown in proliferation medium containing DMEM (Gibco, Life technologies), HAM-F12 L-Glutamine (Gibco®, Life technologies, St Aubin, France) (v/v), 10 % FCS (HyClone), 10 ...
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p14 ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established into nude mice
... can affect pathways and targets other than p53 and demonstrate for the first time that these p53-independent effects can contribute to the tumour suppressive functions of p14 ARF ”in vivo”. They also predicts that loss ...
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Supportive use of platelet-rich plasma and stromal vascular fraction for cell-assisted fat transfer of skin radiation-induced lesions in nude mice
... nine mice per group would be sufficient to show a significant difference between the various products ...female nude NMRI-Foxnu1nu/nu mice (8 weeks old, 28 g) were purchased from the January Lab ...
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Antitumor and radiosensitizing effects of (E)-2'-Deoxy-2'-(Fluoromethylene) cytidine, a novel inhibior of ribonucleotide diphosphate reductase on human colon carcinoma xenografts in nude mice.
... For example, at the same total dose of 100 mg/kg level, the antitumor effects expressed as RD and MV of once daily administration of 10 mg/kg FMdC, 10 times, were more efficient than tha[r] ...
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p14 ARF induces G 2 arrest and apoptosis independently of p53 leading to regression of tumours established into nude mice: p53-independent functions of p14ARF
... prevents phosphorylation and functional inactivation of the retinoblastoma (RB) protein by cyclin-dependent kinases (Serrano et al., 1993). On the other hand, ARF protects against cellular transformation and ...
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Timing effect of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice.
... Compared to the first experiment, very similar results were observed in the four different combined therapy groups, except that more local tumor controls (5 out of 15 mice) were obtained[r] ...
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Combined radiotherapy and radioimmotherapy of human colon carcinoma grafted in nude mice.
... The combined treatment of LS174T tumors with 25 Gy RT and RIT produced a significantly longer tumor regrowth delay than the indi vidual treatments of RT or RIT alone, or RT followed by t[r] ...
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Jaw osteosarcoma models in mice: first description
... immunodeficient mice [ 8 , 28 ] appear to better reproduce the tumor microenvironment and allow a wide range of drugs to be tested by means of a personalized approach for patients [ 29 – 31 ...in nude ...
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Durable and controlled depletion of neutrophils in mice
... C57BL/6 mice were treated with anti-Ly6G 50 μg daily for 9 ...same mice is also shown in the right ...anti-Ly6G mice. b (left) Setting for experiments performed on C57BL/6 mice of >20 ...
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Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice
... bars) mice. Mean ± SEM, n = 3–6 mice per ...1/1 mice. However, in AZIP tg/+ mice, which harbor no inflammation, increase of the LK cell population was observed in all progenitor subsets ...
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The Genotoxin Colibactin Shapes Gut Microbiota in Mice
... KEYWORDS colibactin, enterobacteria, gut microbiota dysbiosis, microbiome T he quantitative and qualitative alterations, named dysbiosis, of the gut microbiota are now considered key traits of multiple pathologies such ...
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Inulin attenuates atherosclerosis in apolipoprotein E-deficient mice
... E-deficient mice were provided by Jackson Laboratories (Charles River Laboratories, L’Arbresle, ...homozygous mice at the Institute animal facility (Unite´ de Nutrition Expe´rimentale, INRA, Theix, ...The ...
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Effect of lyophilized prune extract on hyperhomocysteinemia in mice
... Publisher Pergamon Description Altered homocysteine metabolism defined as hyperhomocysteinemia is implicated as pathogenic factor in several cardiovascular diseases and atherosclerosis. The purpose of this study was to ...
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Study of Leishmania pathogenesis in mice : experimental considerations
... in mice are regulated by genetic determinants ...In mice harboring wild type Scl11a1, such as the CBA mouse strain, parasite proliferation in liver is ...in mice with mutant Scl11a1, such as the ...
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Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice
... Abstract Nucleotide oligomerisation domain 2 (NOD2) is a component of the innate immunity known to be involved in the homeostasis of Peyer patches (PPs) in mice. However, little is known about its role during gut ...
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Adult hematopoietic progenitors are pluripotent in chimeric mice
... iPSCs. Mice obtained from blastocysts inoculated with CD34+ cells differ from mice generated from ESCs or iPSCs where the whole individual is derived from the inoculated stem cells (18,19) as opposed to ...
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