Notch signaling pathway
The Notch signaling pathway involvement in innate lymphoid cell biology
... the Notch signaling pathway (3 ...the Notch pathway. Hence, Notch signaling has a primordial role in enhancing the proliferation of ...that Notch signaling ...
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en fr ADAM10 Membrane Compartmentalization by Tetraspanins : Implications for the NOTCH Signaling Pathway Compartimentation membranaire d’ADAM10 par les tétraspanines : conséquences pour la voie de signalisation NOTCH
... signal Notch Lors de l'activation de la voie Notch, le NICD transloque dans le noyau où il se lie directement au complexe nucléaire et forment un complexe ...de Notch comprennent le NICD, la protéine ...
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NOTCH, a new signaling pathway implicated in holoprosencephaly.
... the NOTCH signaling pathway in the onset of HPE, it also demonstrate that mutation in Dll1 has a modest deleterious functional effect on the ...
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Control of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis
... * lucas.waltzer@univ-tlse3.fr (LW); marc.haenlin@univ-tlse3.fr (MH) Abstract A tight regulation of transcription factor activity is critical for proper development. For instance, modifications of RUNX transcription ...
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Impact of Notch Signaling on Inflammatory Responses in Cardiovascular Disorders
... and Notch signaling pathways appear to be functionally ...increased Notch signaling in neighboring cells ...other Notch ligands, and Dll1 and Jag2 have been reported to be upregulated ...
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Bladder cancer and the Notch pathway
... The Notch signaling pathway is not generally considered a potent activator of the MAPK ...that Notch- deficient bladder cancers (with no other concomitant mutations in FGFR3 or RAS) present ...
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Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis.
... both Notch signaling and klf2a are active in the endothelial cells of the OFT between 48 hpf and 120 ...and Notch activity are high on the luminal side of the developing valve leaflet, which is ...
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C. elegans Notch Signaling Regulates Adult Chemosensory Response and Larval Molting Quiescence
... ical Notch signaling pathway might play a hitherto unsus- pected role in ...elegans Notch receptors LIN- 12 and GLP-1 in octanol avoidance using animals harboring the lin-12(n941) null allele ...
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Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells
... and Notch-1 localization, cells were incubated with N-Rh-PE ...of Notch-1, to Rab5A and to Lamp-1 and detected with Alexa-Fluor 488-labelled secondary ...
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Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway
... Beyond the importance of the therapeutic aspect of identifying new synthetic peptides with antidiabetic potential, the present work also highlights that circulating level of an endogenous peptide could protect beta cells ...
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UNBS5162 inhibits colon cancer growth via suppression of PI3K/Akt signaling pathway
... Akt signaling and decreased expression of PTEN have been found in 60-70% of human colon cancer patients ...mTOR pathway has been also found in colon ...PI3K/Akt/mTOR signaling pathway in colon ...
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Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?
... to signaling pathways such as the Wnt pathway and the TGF-β ...other signaling pathways such as Wnt, sonic hedgehog, or the Hippo signaling pathway cooperate with the TGF-β ...
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Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species
... molecular signaling that allows these plants to recognize their fungal and bacterial ...symbiotic signaling responses to AM fungi in roots of both Casuarina glauca and Discaria tri- nervis, actinorhizal ...
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Ursolic acid increases glucose uptake through the PI3K signaling pathway in adipocytes
... provided a new avenue and been considered having great potential. Ursolic acid (UA) is a natural pentacyclic triterpenoid and present in many different plants, fruits and herbs. Accumulating evidence has shown that UA ...
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Feedback regulation of Gab2-dependent signaling by the Ras/MAPK pathway
... downstream signaling cascades, such as the Ras/MAPK or Rac/JNK pathways (Nishida et ...MAPK signaling in HEK293 cells (Chapter 2, Figure ...Kit signaling in mast ...
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Characterization of protein-protein interactions involved in auxin signaling pathway in tomato
... The first established function of TPL proteins is related to their role in auxin signaling via interaction with Aux/IAA partners (Szemenyei et al., 2008). To check whether this role is conserved among all Sl-TPLs ...
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Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats
... The Notch pathway regulates skeletal muscle prolifera- ...of Notch intermediates was altered in the vitamin D-depleted ...length Notch was unaffected by vitamin D depletion (control ...cleaved ...
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Bone morphogenetic protein signaling pathway plays multiple roles during gastrointestinal tract development.
... Human ENS disorders are fairly common and include Hirschsprung’s disease, a pediatric dysmotility disorder associated with a varying amount of colonic agangliosis (Amiel and Lyonnet, 2001). It is speculative but ...
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Interplay Between Ion Channels and the Wnt/β-Catenin Signaling Pathway in Cancers
... Inserm, CNRS, iBV, Universite ´ Coˆte d’Azur, Nice, France Increasing evidence point out the important roles of ion channels in the physiopathology of cancers, so that these proteins are now considered as potential new ...
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A lymphotoxin-driven pathway to hepatocellular carcinoma.: Sustained hepatic LT signaling causes HCC
... 20 | P a g e cholestatic hepatitis-induced HCC formation in mdr2 -/- mice depends on pathways involving TNFR1 that are distinct from the LTR-dependent pathways described in our own study. We sought to indentify the ...
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