Notch pathway
Bladder cancer and the Notch pathway
... the Notch pathway Pablo ...the Notch pathway in cancer has been known since it was found hyperactivated in acute T-cell lymphoblastic leukemias (T-ALL) one decade ...the Notch ...
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Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.
... of Notch in AJ disassembly is to determine whether Notch acts on the reception and/or integration of the pulling force or directly on the generation of local forces and on control of the expres- sion and/or ...
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Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old Wistar rats
... CONCLUSION : Vitamin D depletion for 9 months efficiently induced vitamin D deficiency in old rats. Vitamin D depletion induces skeletal muscle atrophy in old rats through a reduction in the proliferative ability and in ...
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Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats
... The Notch pathway is involved in SC proliferation [14,79], and PCR arrays showed that the expression of some of the key markers of this pathway were modulated following vitamin D ...a Notch ...
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Perturbations of interactome networks in acute lymphoblastic leukaemia: identification of EXT1 tumor suppressor as a Notch pathway regulator
... the NOTCH pathway through its dual interaction with ALL-related proteins: NOTCH1 and ...the Notch pathway through an FBXW7-dependent ...signalling pathway both at the transcriptional ...
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Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.
... The Notch pathway controls the localisation of Myosin II The chronology of AJ disassembly is essential for the StC flattening and the timing of the MBFC ...
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NOTCH pathway inactivation promotes bladder cancer progression
... the NOTCH pathway could be oncogenic in bladder cancer (37, 38), there is substantial evidence indicating a tumor-suppressive ...the NOTCH pathway ...of NOTCH muta- tions from bladder ...
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en fr Regulation of muscle excitability by the potassium channel EGL-23 and the LIN-12/Notch pathway in the nematode Caenorhabditis elegans Régulation de l’excitabilité musculaire par le canal potassique EGL-23 et la voie de signalisation LIN-12/Notch chez le nématode C. elegans
... Étonnamment nous avons découvert que les 6 neurones appartiennent à deux classes différentes : - Les deux neurones latéraux sont des IL2 : IL2L et IL2R Les quatre neurones dorsaux et ve[r] ...
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La voie Notch - Du développement à la régénération du muscle squelettique
... SUMMARY Notch pathway: from development to regeneration of skeletal muscle In vertebrates, skeletal muscle is derived from mesodermal struc- tures called ...the Notch pathway plays a crucial ...
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Impact of Notch Signaling on Inflammatory Responses in Cardiovascular Disorders
... of Notch in various mechanisms that greatly contribute to the pathogenesis of ...the Notch pathway plays in macrophages, central to the development of inflammation and atherosclerosis, was recently ...
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Notch inhibits yorkie activity in Drosophila wing discs.
... the Notch signaling pathway is both required and sufficient to inhibit the activity of Yorkie (Yki), the Salvador/Warts/Hippo (SWH) pathway terminal transcription activator, but only in the central ...
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Crosstalk between TAF6δ and Notch Signalling Pathways in Cancer Cell Lines
... 1.5.2 TAF6δ It has been reported that the TAF6δ isoform is specifically expressed in apoptotic conditions (Bell et al. 2001). The fact that TAF6δ is generated from TAF6 pre-mRNA alternative splicing has been ...
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LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis
... in Notch activity, but the mechanism by which LKB1 controls Notch activation remains to be ...that Notch-deficient mice dis- played a decrease in the LKB1 activity highlighting a cross-regulation of ...
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Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression
... the Notch pathway in the Drosophila system, we next examined whether this is also the case in ...inhibited Notch-dependent induction of its most sensitive target DTX1 (with a stronger effect of the ...
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Étude de l’interaction Ikaros/voie de signalisation Notch au cours de l'érythropoïèse
... INTRODUCTION: Notch signalling is particularly important for hematopoietic stem/progenitor cells interactions with their niche (environment) (1), and to influence accordingly cell proliferation, differentiation ...
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Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
... Nodal pathway appears to bias the focal activation of FGF signaling to the left, after a significant delay the restriction of FGF activity still occurs in the absence of Nodal activity and the parapineal migrates ...
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A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification
... of Notch pathway targets, which in turn inhibit the PN fate in the future PhR [ 6 ...in Notch/BMP cross ...activate Notch tar- gets during the PN/PhR fate choice but that Notch ...
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The Notch signaling pathway involvement in innate lymphoid cell biology
... of Notch signals could control the cell fate decision during the commitment of lymphoid precursors [ ...The Notch intermittent activation could regulate the proliferation of fetal liver ILC2 precursors ...
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Les cellules B de la zone marginale chez l’homme : un lignage NOTCH 2 dépendant
... vitro les marqueurs des cellules MZB en réponse à un signal donné par le ligand de Notch, Delta Like One (Dll1), nous avons identifié dans la rate humaine deux populations de cellules B potentiellement ...
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Dialogue inter-tissulaire et modulation de la voie Notch contrôlent l’induction de l’hématopoïèse aortique
... de Notch Jag1 et 2 chez les mam- mifères, sont mutuellement exclusives dans l’endothélium aortique ; (2) l’élec- troporation d’un plasmide rapporteur de l’activité de Notch dans l’aorte d’oiseau montre que ...
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