• Aucun résultat trouvé

Nonsense-mediated mRNA decay (NMD)

The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD)

The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD)

... generated nonsense mutations in the viral genome that enable HTLV-1-infected cells to escape from the host immune system in ATL ...an mRNA decay pathway depending on the translation like the NMD ...

21

Premature termination codons in SOD1 causing Amyotrophic Lateral Sclerosis are predicted to escape the nonsense-mediated mRNA decay

Premature termination codons in SOD1 causing Amyotrophic Lateral Sclerosis are predicted to escape the nonsense-mediated mRNA decay

... . Nonsense-mediated mRNA decay (NMD) is an eukaryotic quality control pathway that degrades mRNAs containing Premature termination codons (PTCs) caused by nonsense or frameshift ...

8

Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes

Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes

... RPL41 mRNA and suggested that its very short ORF, encoding only 25 amino acids, was responsible for a lower translation efficiency and for the need of a compensatory increase in mRNA abundance [ 67 ...

14

Identification d’inhibiteurs du nonsense-mediated mRNA decay (NMD) et utilisation comme approche thérapeutique dans certaines maladies génétiques

Identification d’inhibiteurs du nonsense-mediated mRNA decay (NMD) et utilisation comme approche thérapeutique dans certaines maladies génétiques

... De plus, une étude chez la levure a montré que le decapping de l’ARNm peut être initié de façon co-traductionnelle lorsqu’il est encore associé au ribosome dans les fractions polysomal[r] ...

177

Composition et dynamique des complexes protéiques impliqués dans le "nonsense-mediated mRNA decay" chez la levure Saccharomyces cerevisiae

Composition et dynamique des complexes protéiques impliqués dans le "nonsense-mediated mRNA decay" chez la levure Saccharomyces cerevisiae

... To establish how NMD4 and EBS1 could affect NMD substrates, we searched for conditions that would simplify our phenotypic analysis. We chose to focus on the helicase and C- terminal domain of Upf1, important for binding ...

193

Nonsense-Mediated Decay Restricts LncRNA Levels in Yeast Unless Blocked by Double-Stranded RNA Structure

Nonsense-Mediated Decay Restricts LncRNA Levels in Yeast Unless Blocked by Double-Stranded RNA Structure

... for mRNA turn- over in the cytoplasm. Several mRNA decay pathways lead to degradation by Xrn1 ( Parker, 2012 ...general mRNA decay pathways involve shortening of the poly(A) tail ( ...

16

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.

... of nonsense suppression at termination codons in a variety of yeast genes (reviewed in ...and nonsense-mediated mRNA decay, sug- gesting that GTP/eRF3-dependent termination exerts its ...

13

On decay constants and orbital distance to the Sun. Part I: alpha decay

On decay constants and orbital distance to the Sun. Part I: alpha decay

... Am decay constant down to sub-permille ...704 decay rate measurements were performed between 2014 and 2016 by means of a commercial TriCarb 2810 TR liquid scintillation ...and decay-corrected count ...

19

The Decay Data Evaluation Project (DDEP) and the JEFF-3.3 radioactive decay data library: Combining international collaborative efforts on evaluated decay data

The Decay Data Evaluation Project (DDEP) and the JEFF-3.3 radioactive decay data library: Combining international collaborative efforts on evaluated decay data

... recommended decay data to ...main decay radiations (alpha, beta and gamma) and the associated atomic data due to the internal conversion process, ...recommended decay data relevant to the wider user ...

7

Cytoplasmic Control of Sense-Antisense mRNA Pairs

Cytoplasmic Control of Sense-Antisense mRNA Pairs

... these mRNA-mRNA interactions in wild-type cells was demonstrated by the fact that the presence of the OCA2 mRNA interferes with 3 0 –5 0 mRNA degradation of the POR1 mRNA and leads to ...

14

Dissemination and visualisation of reference decay data from Decay Data Evaluation Project (DDEP)

Dissemination and visualisation of reference decay data from Decay Data Evaluation Project (DDEP)

... All necessary data are stored in one single database, N UCL EIDE ´ , which is used as an entry point and has allowed the development of specific software to maintain and update this database. The LNHB is therefore able ...

5

On decay constants and orbital distance to the Sun—part I: alpha decay

On decay constants and orbital distance to the Sun—part I: alpha decay

... repeated decay rate measurements of 32 Si/ 36 Cl and 226 Ra were due to an annual modulation of the decay constants rather than instabilities in the detection system [ 17 , 18 ...Mn decay rates ...

20

On decay constants and orbital distance to the Sun—part II: beta minus decay

On decay constants and orbital distance to the Sun—part II: beta minus decay

... non-exponential decay. However, also the conjecture that cosmic neutrinos stimulate decay has been further developed: Sturrock et al [ 20 ] found arguments to claim that there is a directional relationship ...

18

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

... selected mRNA demonstrated that binding of the 30S ribo- some subunit confers DMS protection for the nucleotides of the SD sequence ( H€uttenhofer and Noller, 1994 ...

23

Algorithms for simulating human pre-mRNA splicing decisions

Algorithms for simulating human pre-mRNA splicing decisions

... With a high cutoff, only high-scoring exons will be predicted. These exons are likely to be correct; however, the simulation will tend to miss low- and medium- sc[r] ...

38

CUORE sensitivity to 0νββ decay

CUORE sensitivity to 0νββ decay

... use of different algorithms, e.g. nested sampling [ 35 , 36 ], or a partial analytical solution of the likelihood maximization. We perform two further cross-checks in order to investi- gate the relative importance of the ...

11

CUORE sensitivity to 0νββ decay

CUORE sensitivity to 0νββ decay

... – E represents the data. It is a list of N energy bins cen- tered at the energy E i and containing n i event counts. The energy range is [2470; 2570] keV. This is the same range used for the CUORE-0 0 νββ decay ...

11

Angular analysis of the decay

Angular analysis of the decay

... the decay rate for the B þ → K þ μ þ μ − process: the forward-backward asymmetry A FB of the dimuon system and the contribution F H from the pseudoscalar, scalar, and tensor amplitudes to the decay ...the ...

21

Environmentally Mediated Social Dilemmas

Environmentally Mediated Social Dilemmas

... At present, theoretical work on environmentally-mediated social interactions has largely focused on simple non-spatial settings (except, notably, work on biofilms; e.g, [13-17]), while the broader field of social ...

21

Mécanismes modulant l'épissage alternatif du pré-mRNA de la NCAM murine

Mécanismes modulant l'épissage alternatif du pré-mRNA de la NCAM murine

... L'élément exonique que nous avons identifié est situé dans un exon constitutif (El 7) et influence les profils d'épissage d'un exon alternatif adjacent (El8). Cette influence sur l'[r] ...

135

Show all 1295 documents...

Sujets connexes