Non-alcoholic fatty liver disease (NAFLD)
In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal
... organoids; liver-on-a-chip; cell culture 1. Introduction Non-alcoholic fatty liver disease (NAFLD) comprises two histological forms: non- alcoholic fatty ...
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Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy
... of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with ...distant Non-Tumoral Tissue (NTT) collected from ...
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Identifying PGC-1α-dependent hepatokines in a non-alcoholic fatty liver disease murine model
... Non-alcoholic fatty liver disease (NAFLD) has become a serious public health problem and is now considered as the major cause of liver disease ...of liver diseases ...
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Cannabis use is associated with reduced prevalence of non-alcoholic fatty liver disease: A cross-sectional study
... for non-alcoholic fatty liver disease (NAFLD), the most prevalent liver disease ...groups: non-cannabis users (98.04%), non-dependent cannabis users ...and ...
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Specificities of Hepatocellular Carcinoma Developed on Non Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue 1H-NMR Spectroscopy
... in Non Alcoholic Fatty Liver Disease (NAFLD) occurs in 40% of cases in the absence of cirrhosis and therefore may escape detection enabled by systematic screening of cirrhotic patients ...
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Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment
... Non-alcoholic fatty liver disease (NAFLD) is often associated with obesity and type 2 ...and disease-related phenotypes in a mouse F2 cross derived from strains showing ...
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Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease
... affects liver function. Non-alcoholic fatty liver disease (NAFLD) is the most common etiology of chronic liver disease affecting 25% of the general population ...
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en fr Progression and diagnostic methods in non-alcoholic fatty liver disease Progression et tests diagnostiques de la stéatose hépatique non alcoolique
... against liver biopsy, neither compared head-to-head in a single ...The Fatty Liver Index has been developed in a cohort of patients from the general population with ultrasound- diagnosed hepatic ...
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Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials
... NAFLD, non-alcoholic fatty liver disease; NW, normal weight; OB, obese; OW, overweight, T2DM, type 2 diabetes mellitus, WC, waist ...
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Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context
... that fatty liver does not affect renal function and CKD development can be induced only by an alteration of intra-renal metabolism and without hepatic steatosis, whereas many recent studies suggested a ...
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Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease
... chronic liver disease, complicated cirrhosis, or received putative antifibrotic treatment in the past 6 ...months. Liver biopsies were performed at Taleghani Hospital in 2012-2013 using a Meghini ...
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Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome
... measures, liver histology, hepatic lipid measurements and liver genome-wide gene transcription profiling in C57BL/6J and BALB/c mice fed either a control or a high fat ...and non alcoholic ...
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Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease
... in fatty acid catabolism (Hmgcs2, Acox, Cyp4a, Ehhadh, Acad, Cpt1a, Cpt2, Cd36, Slc27a1, Fabp1) [235,237,321,322], autophagy (Atg, Tfeb) [248,249], and glycerol metabolism (Gyk, Gpdh) [255], and regulates ...
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Nine-year incident diabetes is predicted by fatty liver indices: the French D.E.S.I.R. study.
... These fatty liver indexes are simple clinical tools for evaluating the extent of liver fat and they are predictive of incident ...with fatty liver. Background ...
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Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma
... 1* Non‑alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western ...progressive non‑alcoholic steatohepatitis (NASH) that can lead to ...
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Roles of Ceramides in Non-Alcoholic Fatty Liver Disease
... (muscles, liver, pancreatic ß-cells) leads to the synthesis of specific lipids, such as sphingolipids (SL) which interfere with insulin ...of fatty acids from adipocytes into the ...of fatty acids to ...
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The purinergic p2x7 receptor-nlrp3 inflammasome pathway: A new target in alcoholic liver disease?
... of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis, suggesting possible therapeutic strategies targeting the P2X7 receptor/NLRP3 inflammasome [ 99 ...of liver ...
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View of Non Alcoholic Fatty Liver Disease and Non Alcoholic Steato-Hepatitis are Multisystemic Diseases: Review for Intensivists
... est non invasive, économique, sans risque mais peu ...ou non de la présence de ...diagnostic non invasif de la fibrose hépatique et de la cirrhose et de plus permet de diagnostiquer la NASH mais ...
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European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease?
... summary: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent condition that can be optimally ...
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Rôle du régulateur du cycle cellulaire p16INK4a dans le développement du diabète de type 2 et dans les maladies métaboliques du foie gras ou NAFLD (Non-Alcoholic Fatty Liver Disease) : rôle de p16INK4a dans le contrôle de la néoglucogenèse hépatique et dans le développement de la stéatose hépatique non alcoolique.
... Sarah Anissa Hannou 1,2,3,4 , Kristiaan Wouters 1,2,3,4,5 , Bart Staels 1,2,3,4 and Réjane Paumelle 1,2,3,4 Abstract Genome-wide association studies (GWAS) provide an unprecedented opportunity to examine, on a large ...
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