NAFLD = Non-alcoholic fatty liver disease
Rôle du régulateur du cycle cellulaire p16INK4a dans le développement du diabète de type 2 et dans les maladies métaboliques du foie gras ou NAFLD (Non-Alcoholic Fatty Liver Disease) : rôle de p16INK4a dans le contrôle de la néoglucogenèse hépatique et dans le développement de la stéatose hépatique non alcoolique.
... Les lipides alimentaires sont émulsionnés dans le tractus intestinal par les acides biliaires (BA : bile acids) secrétés par le foie. Les lipides hydrolysés sont ensuite absorbés par les entérocytes et emballés dans des ...
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Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials
... insulin; NAFLD, non-alcoholic fatty liver disease; NW, normal weight; OB, obese; OW, overweight, T2DM, type 2 diabetes mellitus, WC, waist ...
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Roles of Ceramides in Non-Alcoholic Fatty Liver Disease
... 1.2. NAFLD, Obesity and Diabetes Obesity and Type 2 diabetes (T2D) are two conditions leading to an increased preva- lence of ...(muscles, liver, pancreatic ß-cells) leads to the synthesis of specific ...
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Natural History of NAFLD
... Keywords: fatty liver; fibrosis; metabolic syndrome; insulin resistance ...of non-alcoholic fatty liver disease (NAFLD) continues to increase with almost 1 billion ...
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Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease
... ED NAFLD [28], without any pattern suggestive of other ...chronic liver disease, complicated cirrhosis, or received putative antifibrotic treatment in the past 6 ...months. Liver biopsies were ...
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Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy
... of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with ...the NAFLD etiology, we performed comparative ...
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Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment
... Non-alcoholic fatty liver disease (NAFLD) is often associated with obesity and type 2 ...in NAFLD processes, we mapped 1 H nuclear magnetic resonance (NMR) metabolomic and ...
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en fr Progression and diagnostic methods in non-alcoholic fatty liver disease Progression et tests diagnostiques de la stéatose hépatique non alcoolique
... against liver biopsy, neither compared head-to-head in a single ...The Fatty Liver Index has been developed in a cohort of patients from the general population with ultrasound- diagnosed hepatic ...
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Cannabis use is associated with reduced prevalence of non-alcoholic fatty liver disease: A cross-sectional study
... of NAFLD with cannabis use ( Fig 1 ) suggesting that cannabis use might suppress or reverse NAFLD ...of NAFLD was associated with known factors including age 40–60 years, female gender, ...
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Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context
... that fatty liver does not affect renal function and CKD development can be induced only by an alteration of intra-renal metabolism and without hepatic steatosis, whereas many recent studies suggested a ...
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Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease
... driving NAFLD development and progression, ...in fatty acid catabolism (Hmgcs2, Acox, Cyp4a, Ehhadh, Acad, Cpt1a, Cpt2, Cd36, Slc27a1, Fabp1) [235,237,321,322], autophagy (Atg, Tfeb) [248,249], and glycerol ...
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European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of fatty liver disease?
... The NAFLD Preparedness Index indicates substantial variation between countries ’ readiness to address ...optimise NAFLD management and ensure effective public health approaches are in ...summary: ...
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Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome
... measures, liver histology, hepatic lipid measurements and liver genome-wide gene transcription profiling in C57BL/6J and BALB/c mice fed either a control or a high fat ...and non alcoholic ...
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Specificities of Hepatocellular Carcinoma Developed on Non Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue 1H-NMR Spectroscopy
... in Non Alcoholic Fatty Liver Disease (NAFLD) occurs in 40% of cases in the absence of cirrhosis and therefore may escape detection enabled by systematic screening of cirrhotic ...
2
The purinergic p2x7 receptor-nlrp3 inflammasome pathway: A new target in alcoholic liver disease?
... of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis, suggesting possible therapeutic strategies targeting the P2X7 receptor/NLRP3 inflammasome [ 99 ...of ...
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Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma
... 1* Non‑alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western ...progressive non‑alcoholic steatohepatitis (NASH) that can ...
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Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes
... patients. Liver biopsies from subjects with suspected non-alcoholic fatty liver disease are analyzed for sphingolipid synthesis enzyme ...nonalcoholic fatty liver ...
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Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease
... in NAFLD has become a subject of considerable ...the non-parenchymal fraction of the liver has not been ...influence liver inflammation seen in ...the liver from pathogenic stresses ...
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View of Non Alcoholic Fatty Liver Disease and Non Alcoholic Steato-Hepatitis are Multisystemic Diseases: Review for Intensivists
... la NAFLD, la NASH et l ...la NAFLD augmente de deux fois le risque d ’incidence de survenue du diabète de type 2 et du SM et que la NAFLD est prédictive de la sur- venue du SM sur une période moyenne ...
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Identifying PGC-1α-dependent hepatokines in a non-alcoholic fatty liver disease murine model
... the liver from damaging ...in NAFLD pathogenesis, it remains that SERPINA3N secreted levels could be a potential biomarker of the liver state, as an indicator of disrupted hepatic PGC-1α ...
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