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NADPH oxidase complex

p47 phox Molecular Activation for Assembly of the Neutrophil NADPH Oxidase Complex

p47 phox Molecular Activation for Assembly of the Neutrophil NADPH Oxidase Complex

... Neutrophil NADPH Oxidase Complex * □ S Received for publication, April 30, 2010, and in revised form, June 28, 2010 Published, JBC Papers in Press, June 30, 2010, DOI ...

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Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase

Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase

... transiently transfected with the three cytosolic subunits with or without a FP-tag (Fig. 2A). The production of superoxide anions was monitored by a luminometry assay sensitive to extracellular ROS (Fig. 2B). The ROS ...

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The physicochemical properties of membranes correlate with the NADPH oxidase activity

The physicochemical properties of membranes correlate with the NADPH oxidase activity

... the NADPH oxidase complex. In phagocyte cells, the NADPH oxidase complex converts the chemical reducing equivalent of NADPH into superoxide anions (O 2 •- ) in the ...

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Activation of the phagocyte NADPH oxidase/NOX2 and myeloperoxidase in the mouse brain during pilocarpine-induced temporal lobe epilepsy and inhibition by ketamine

Activation of the phagocyte NADPH oxidase/NOX2 and myeloperoxidase in the mouse brain during pilocarpine-induced temporal lobe epilepsy and inhibition by ketamine

... production of the immune cells in the CNS. The dose used in this experimentation was, however, particularly high (Hayashi et al. 2011). Moreover, Weigand et al. 2000 indicate that ketamine can attenuate important ...

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Effet des agonistes des TRL sur la production des FRO par la NADPH oxydase des polynucléaires neutrophiles humains

Effet des agonistes des TRL sur la production des FRO par la NADPH oxydase des polynucléaires neutrophiles humains

... the NADPH oxidase enzyme complex (also called NOX2) [6, ...the NADPH oxidase complex mediates the transfer of electrons from cytosolic NADPH to oxygen to produce ...

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Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells: Mitotane-induced cytochrome c oxidase defect

Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells: Mitotane-induced cytochrome c oxidase defect

... c oxidase; DNA: Deoxyribose nucleic acid; DMSO: dimethyl sulfoxide; mRNA: messenger Ribonucleic acid; mt: Mitochondrial; NADH: reduced Nicotinamide adenine dinucleotide; o,p’-DDD: 1,1-dichloro-2-(o- ...

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NADPH oxidases in Parkinson’s disease: a systematic review

NADPH oxidases in Parkinson’s disease: a systematic review

... Microglial Nox2 expression is increased in PD and experimental models of PD In 2003, Przedborski and coworkers reported that post- mortem substantia nigra samples from sporadic PD pa- tients had higher Nox2 (then ...

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Evolutive differentiation between alga-and plant-type plastid terminal oxidase: study of plastid terminal oxidase PTOX isoforms in Marchantia polymorpha

Evolutive differentiation between alga-and plant-type plastid terminal oxidase: study of plastid terminal oxidase PTOX isoforms in Marchantia polymorpha

... lower V max than MpPTOXa. This would make MpPTOXa the more efficient enzyme keeping the PQ pool oxidized under conditions favouring linear electron flow. The proposition of a high activity of MpPTOXa is supported by the ...

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Étude de la modulation de l'activité et de l'expression de la NADPH-réductase par la réaction inflammatoire

Étude de la modulation de l'activité et de l'expression de la NADPH-réductase par la réaction inflammatoire

... Par ailleurs, il a été rapporté que lors de la réaction inflammatoire produite par l'injection de térébenthine, l'induction de l'hème oxygénase hépatique est médiée par l'[r] ...

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Modulation de l'expression et de l'activité de la NADPH P450 réductase chez le lapin

Modulation de l'expression et de l'activité de la NADPH P450 réductase chez le lapin

... La NADPH P450 réductase (NPR) est une flavoprotéine donatrice ...la NADPH et contenant un groupe prosthétique FMN (Flavin mononucleotide) (Haas et ...

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Le complexe de la NADPH oxydase : études structurales des facteurs cytosoliques.

Le complexe de la NADPH oxydase : études structurales des facteurs cytosoliques.

... ÉTUDE PAR CRISTALLOGRAPHIE DES RAYONS X DES FACTEURS CYTOSOLIQUES DU COMPLEXE DE LA NADPH OXYDASE .............................. 87 : ) %*+5) % . . 04 ...

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PKB mediates Insulin-Like Growth Factor 1-induced phosphorylation and nuclear export of Histone Deacetylase 5 via NADPH Oxidase 4 activation in vascular smooth muscle cells

PKB mediates Insulin-Like Growth Factor 1-induced phosphorylation and nuclear export of Histone Deacetylase 5 via NADPH Oxidase 4 activation in vascular smooth muscle cells

... (NAD(P)H oxidase inhibitor) were purchased from Calbiochem (San Diego, CA, ...(NAD(P)H oxidase inhibitor) was purchased from Cayman Chemical (Ann Arbor, MI, ...

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Les NADPH oxydases, Nox - Une nouvelle famille d’isoenzymes

Les NADPH oxydases, Nox - Une nouvelle famille d’isoenzymes

... évolué à partir d’un ancêtre commun (Tableau I) . Cette famille se subdivise en deux groupes selon la capacité des Nox à constituer un hétérodimère avec p22phox (Nox1, -2, -3 et -4) ou selon la présence dans la séquence ...

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Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase

Proton-transfer pathways in the mitochondrial S. cerevisiae cytochrome c oxidase

... 38. Gilderson, G., Aagaard, A. & Brzezinski, P. Relocation of an internal proton donor in cytochrome c oxidase results in an altered pK(a) and a non-integer pumping stoichiometry. Biophys. Chem. 98, 105–114 ...

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Semicarbazide-sensitive amine oxidase substrates in obesity and diabetes

Semicarbazide-sensitive amine oxidase substrates in obesity and diabetes

... vivo and in vitro, thus SSAO has been proposed as a therapeutic target in diabetes. A small SSAO activity was also detectable without addition of BzA, likely due to the oxidation of end[r] ...

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Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis

Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis

... monoamine oxidase (MAO) family member, LkcE, catalyzes both an unusual amide oxidation, and a subsequent intramolecular Mannich reaction to form the polyketide ...

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Inhibitory Activity on Xanthine Oxidase and Antioxidant Properties of Teucrium polium L. Extracts

Inhibitory Activity on Xanthine Oxidase and Antioxidant Properties of Teucrium polium L. Extracts

... ferrous-TPTZ complex was sta- ble at this time ...ferric-TPTZ complex was not established after 4 min re- action time and most of the compound shows a steady increase in the absorbance with time, therefore ...

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Thermosensibilité des propriétés fonctionnelles du complexe cytochrome c oxidase-cytochrome c et coévalution des génomes mitochondrial et nucléaire

Thermosensibilité des propriétés fonctionnelles du complexe cytochrome c oxidase-cytochrome c et coévalution des génomes mitochondrial et nucléaire

... Arctic charr showed higher Vmax values , significantly different from ail tluee other species at ail temperatures (figure 2a). This could be attributed to a higher content [r] ...

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Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

... lysyl oxidase-like 4 (LOXL4) expression by atRA in the corneal epithelium environment was established as essential in the mechanism of atRA-dependent wound ...

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Influence du chondroïtine sulfate (CS) 
sur l’activité et l’expression de plusieurs isoformes du cytochrome P450 
et de la NADPH P450 réductase

Influence du chondroïtine sulfate (CS) sur l’activité et l’expression de plusieurs isoformes du cytochrome P450 et de la NADPH P450 réductase

... 63 Patients with infectious and/or inflammatory diseases may present transient decreases in the activity of the mixed function oxidase system (Chang et al., 1978; Sonne et al., 1985). In animals, a ...

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