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N-type calcium channel

Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins.

Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins.

... N-type channel regulation by G-proteins N-type channel regulation by G-proteins can be described accurately by three parameters: the G-protein inhibition level at the onset of depolarization ...

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Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability

Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability

... T-type calcium channels are critically involved in neuronal excitability, especially in burst firing, in low-threshold calcium spikes (LTCS) and rebound action potential (AP), as reviewed by Cain ...

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The L-type calcium channel blockers, Hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants

The L-type calcium channel blockers, Hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants

... P., and Weglicki, W. B. (1995) Protective effects of calcium channel blockers against free radical-impaired endothelial cell proliferation. Biochem. Pharmacol . 50, 1531-1534. (9) (a) Ingold, K. U. (1961) ...

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Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons

Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons

... Azimi-Zonooz A, Kawa CB, Dowell CD, Olivera BM. (2001). Autoradiographic localization of N-type VGCCs in gerbil hippocampus and failure of omega-conotoxin MVIIA to attenuate neuronal injury after transient ...

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Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop

Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop

... Voltage-dependent calcium channels (Cav) of the T-type fam- ily ...T-type channel activity, espe- cially ...and channel gating, indicat- ing that this I-II loop plays an important ...

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Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons

Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons

... T-type channel inhibitor TTA-A2 (1 µM) signif- icantly decreased the rebound amplitude during the first subthreshold step and abolished action potential firing during the second suprathreshold step (n = 7, ...

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en fr Role of calcium-activated chloride channel TMEM16F in motricity and implication in amyotrophic lateral sclerosis Rôle du canal chlorure activé par le calcium TMEM16F dans la motricité et implication dans la sclérose latérale amyotrophique

... motor-unit type (Zengel et ...into type 1, 2 and 3 populations (Figure 3A, B) which is mainly representative of the slow a motoneurons (S) and γ motoneurons, the fast resistant (FR) and the fast fatigable ...

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The Effects of Pro-inflammatory Cytokines on the L-type Calcium Current in Mouse Ventricular Myocytes

The Effects of Pro-inflammatory Cytokines on the L-type Calcium Current in Mouse Ventricular Myocytes

... able to directly induce changes in cardiac electrical properties thus directly contributing to an increased risk of arrhythmia. In an attempt to answer these questions, our lab has devised a complete research axis which ...

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en fr Spinal T-type calcium channels and pain sensitivity Canaux calciques de type T spinaux et sensibilité douloureuse

... Cav3.2 channel in neuropathic pain establishment and ...T type channels, depend on the presence of ...T- type blocker that is orally available and peripherally restricted, showed negative results in ...

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Activation of PAC1 receptors in rat cerebellar granule cells stimulates both calcium mobilization from intracellular stores and calcium influx through N-type calcium channels

Activation of PAC1 receptors in rat cerebellar granule cells stimulates both calcium mobilization from intracellular stores and calcium influx through N-type calcium channels

... L-type calcium channel conductance by activating the MAPK pathway ( Dziema and Obrietan, 2002 ...transient calcium mobilization ( Dziema and Obrietan, 2002 ) or increase the amplitude and/or ...

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Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells

Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells

... Ca 2+ channel currents were recorded using the whole-cell patch-clamp technique with a Biologic RK400 amplifier (Bio- logic, France). Data acquisition and analysis were performed using the pCLAMP system (Axon ...

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T-type calcium channels in neuropathic pain

T-type calcium channels in neuropathic pain

... new calcium channel therapeutics with a low risk of side ...T-type calcium channels are formed by a single Cavα1 subunit – a ~250 KDa protein that is comprised, as for the HVA calcium ...

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How do T-type calcium channels control low-threshold exocytosis?

How do T-type calcium channels control low-threshold exocytosis?

... Arnoult C, De Waard M. Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel ...

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The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function

... To investigate this, we designed a knockin (KI) strategy by in- serting a two loxP site-flanked ecliptic-GFP tag into exon 6 of the Cav3.2 locus to allow genetic marking of Cav3.2 channels as well as tissue-specific loss ...

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Apport des silicates de calcium en endodontie

Apport des silicates de calcium en endodontie

... de calcium, ...of calcium silicates in endodontics Abstract : According to Schilder, the success of endodontic treatment depends on the respect of the triad: cleaning, shaping, ...sealer, calcium ...

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Synthèse de nanoparticules de carbonate de calcium

Synthèse de nanoparticules de carbonate de calcium

... synthesize calcium carbonate nanoparticles by various methods such as precipitation in aqueous phase, simple emulsion and double ...and calcium and carbonate ions concentrations on the size and the ...

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Estimation of Clustered MIMO Channel Parameters exploiting Channel Statistics

Estimation of Clustered MIMO Channel Parameters exploiting Channel Statistics

... the channel, such that τ l is the mean delay and σ l is the standard deviation of the delay spreading of cluster l ; α l (τ ; ξ l ) is the complex gain in the cluster, where for a fixed ξ l , α l (τ ; ξ l ) is a ...

2

Calcium et contrôle de la photosynthèse C4

Calcium et contrôle de la photosynthèse C4

... Le clonage de l’ADNc et des gènes de PEPC kinase (PEPCk) a été réalisé récemment à partir de plantes C 3 , C 4 et CAM [3, 4] , permettant d’établir la structure primaire de l’enzyme et de révéler des caractéristi- ques ...

3

Ultrafast Synthesis of Calcium Vanadate for Superior Aqueous Calcium-Ion Battery

Ultrafast Synthesis of Calcium Vanadate for Superior Aqueous Calcium-Ion Battery

... Recently, multivalent aqueous calcium-ion batteries (CIBs) have attracted considerable attention as a possible alternative to Li-ion batteries. However, traditional Ca-ion storage materials show either limited ...

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Ultrafast Synthesis of Calcium Vanadate for Superior Aqueous Calcium-Ion Battery

Ultrafast Synthesis of Calcium Vanadate for Superior Aqueous Calcium-Ion Battery

... Recently, multivalent aqueous calcium-ion batteries (CIBs) have attracted considerable attention as a possible alternative to Li-ion batteries. However, traditional Ca-ion storage materials show either limited ...

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