myeloid differentiation
<em>Bradyrhizobium</em> Lipid A: Immunological Properties and Molecular Basis of Its Binding to the Myeloid Differentiation Protein-2/Toll-Like Receptor 4 Complex
... and myeloid differentiation protein-2 (MD-2) on the plasma membrane of immune cells thus activating downstream signaling pathways leading to a rapid release of inflammatory cytokines ( 1 , 5 ...
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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
... Systems) at 10 6 cells/ml. All the samples were then processed for treatment with different reagents. Targeted resequencing. A panel of 31 genes frequently mu‑ tated in AML and myeloid malignancies, including ...
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en fr Checkpoint kinase 1 : its novel functions during normal myeloid differentiation ans its role as prognostic marker and therapeutic target in acute myeloid leukemia Etude de nouvelles fonctions de la protéine checkpoint kinase 1 (Chk1) au cours de la différenciation myéloïde normale et leucémique
... En effet, dans le contexte de la différenciation myéloïde, le niveau d’expression ou de phosphorylation de Chk1 pourrait régir l’état de prolifération versus l’état de différenc[r] ...
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The Branching Point in Erythro-Myeloid Differentiation
... the myeloid or the erythroid ...producing myeloid cells (M, left panel) or erythroblasts (E, right panel)) versus barcoded CMPs classified as bi-outcome (producing both E and M, M+E, with the E and M read ...
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Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia
... unknown in other karyotype and mutational patient sub- groups with adverse risks, such as patients with p53, RAS, or CEBPα mutations, or monosomic complex kar- yotypes in AML. Notably, Fenouille et al. have shown that ...
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CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia
... nice differentiation of treated leukemic cells in vitro and clinically with cases of differentiation syndrome ...hematopoietic differentiation process in vivo ...this differentiation, suggest ...
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Neural stem cells plasticity and differentiation
... SUMMARY Neurons and glia differentiate from multipotent precursors called neural stem cells (NSCs), upon the activation of specific transcription factors. In vitro, it has been shown that NSCs display very plastic ...
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Genetic differentiation within and among refugia
... distances of less than 30 km, but well in the range 30 to 400 km (Peterson 1995, 1996). The lack of correlation at small distances was related to the ecological heterogeneity at small scale, such as local topography, ...
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Probalilistic duopoly with differentiation by attributes
... two-dimensional differentiation have already been proposed by Neven and Thisse (1990), Economides (1993) and Irmen and Thisse ...of differentiation in the DBA model (for example, an increase of u 2 reduces ...
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The differentiation of hypoelliptic diffusion semigroups
... The paper is organized as follows. In Section 2 we collect some background on Malliavin calculus related to hypoelliptic diffusions. In Section 3 we explain our ap- proach to integration by parts in the hypoelliptic case ...
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Airline pricing and fare product differentiation
... relationship, perceived fare product degradation costs, available seat supply, and the ability of the airline to segment the consumer population. Comparative statics analysis techniqu[r] ...
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International labour standards and product differentiation
... ILO Declaretion of 1998: no forced labor; freedom of assosiation; no discrimination at the workplace; elimination of child labor. Note that undercomplying with CLS is often the case in s[r] ...
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On production costs in vertical differentiation models
... vertical differentiation model with fixed cost for quality improvement is not ...product differentiation and thus prices, whereas a high unit cost leads to raise product differentiation and ...
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CD8 T cell differentiation during immune responses
... memory differentiation (Tbet and Eomes); receptors of molecules involved in the responsiveness to environmental cues: IL-10R, IL-12Rb1 and IL-21R; inhibitory molecules such as KLRG1 and PD1 (associated with ...
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Stability of the cell dynamics in acute myeloid leukemia
... Some preliminary sufficient conditions for local asymptotic stability of 1- stage Acute Myeloid Leukemia PDE model were presented in [4]. Notation and preliminaries: Throughout the paper the superscript ‘T ’ ...
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Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia
... acute myeloid leukemia (sAML), occurring after antecedent hematologic diseases, previous chemotherapy or radiation, has an inferior prognosis compared with de novo ...
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Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry
... The monocyte/phagocyte system (MPS) is a complex cellular compartment that includes phenotypically and functionally heterogeneous populations of cells, including monocytes, macrophages (M Φ), and dendritic cells (DC) ...
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A scheduler for relative delay service differentiation
... service differentiation among classes, into two categories: category A contains propositions which oblige having separate queues per class whereas in cate- gory B, the algorithms do not require separate queues per ...
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A novel role for myeloid endothelin-B receptors in hypertension
... This reduction in media ET-1 was seen when BMDM were exposed to increasing concentrations of ET-1 (Figure 4 B) and was not explained by degradation of the peptide over the 24 h period (s[r] ...
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Regulatory myeloid cells: an underexplored continent in B-cell lymphomas
... Controlling the expansion and accumulation of MDSCs and blocking MDSC suppressive functions, e.g. by targeting CSF1-R (colony stimulating factor 1 receptor) [98] or S100 family members [99], represent promising novel ...
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