Muscarinic receptors
Neurobiology of Disease Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease
... of muscarinic receptors may ei- ther reduce or enhance striatal DA release depending on the stud- ies, suggesting that these interactions are more complex than was originally thought ( Eskow Jaunarajs et ...
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Localisation of functional muscarinic receptors in the rat cochlea: evidence for efferent presynaptic autoreceptors
... Furthermore, indirect evi- dence associating muscarinic receptors to the outer region of this organ is found in the following spatio- temporal correlation: the mus[r] ...
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Cholinergic modulation inhibits cortical spreading depression in mouse neocortex through activation of muscarinic receptors and decreased excitatory/inhibitory drive
... 12 postsynaptic currents (sIPSCs) recorded at +10mV from pyramidal neurons of layer 2-3, without using any blockers of glutamatergic or GABAergic receptors (Fig 6). These experiments provide a measure of the ...
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Muscarinic M1 Receptor Modulation of Synaptic Plasticity in Nucleus Accumbens of Wild-Type and Fragile X Mice
... distinct muscarinic acetylcholine receptor (mAChR) subtypes (M 1 −M 5 ) are expressed in the brain, 2 , 3 and quantitative autoradiographic studies have demonstrated that the striatum has one of the highest ...
9
The neurotoxic effect of 13, 19-didesmethyl and 13-desmethyl spirolide C phycotoxins is mainly mediated by nicotinic rather than muscarinic acetylcholine receptors.
... on muscarinic receptors (mAChRs), functional electrophysiological studies and competition binding experiments have been ...a7 receptors and recognized only weakly neuronal heteropentameric ...
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Simultaneous activation of muscarinic and GABAB receptors as a bidirectional target for novel antipsychotics
... of muscarinic receptors were active in DOI-induced head ...All muscarinic acti- vators when administered alone or in combination with GS39783 reversed the MK-801-induced disruption of memory in the ...
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Interactions between neurotensin receptors and G proteins.
... independent of G protein activation, these two events are described by different parameters in the cubic model. The ability of G to alter the affinity of the ligand for R is represented by , while the ability of a ...
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Heteromerization of human cytomegalovirus encoded chemokine receptors
... in the presence of UL33 and UL78 was unlikely to be due to altered expression levels of the receptors, since they remained relatively stable under the different experimental conditions (see Figs. 5B, C, E & ...
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Corticosteroid receptors adopt distinct cyclical transcriptional signatures
... PER1 promoter as homodimers, and that MR–GR heter- odimers also interact with genomic targets. DISCUSSION In the current study, we provide new insights into how the corticosteroid signaling pathway is physiologically ...
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Dependence receptors: mechanisms of an announced death.
... as receptors with adaptors or effectors of signaling pathways such as ...dependence receptors with lipid rafts, either to control the positive pathway ...dependence receptors lose their ability to ...
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Molecular characterization of cortisol receptors in fish
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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Ethylene receptors modulate fruit development and ripening
... of receptors have different roles in controlling fruit ripening with the early induced genes having a larger role in fruit ...other receptors that are up-regulated later in fruit ...
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Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors.: Profiling of estrogen receptors environmental ligands
... thyroid or adrenal glands, bone and some regions of the brain. Although ERα and ERβ share similar mechanisms of action, several differences in the transcriptional abilities of each receptor, as well as distinct ...
31
[Lifespan and IGF receptors in the brain.]
... mammifères, nous avons génétiquement manipulé la signalisation IGF spécifiquement dans le cerveau, puis exploré croissance, métabolisme et durée de vie chez ces mutants [14, 31].. Mo[r] ...
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Modulation of Oxytocin Receptors in Right Ventricular Hypertrophy
... hypertension is unknown. We can speculate that the increased synthesis of these peptides in LV is associated with stretch of ventricles and increased plasma ANP and BNP levels observed in MCT-treated rats [Usui et al ...
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View of Baclofen Intoxication and GABA Receptors
... Chez notre patient, la dose ingérée présumée était inconnue, et la concentration maximale de valproate mesuré à 120 mg/l (valeur résiduelle) à minuit de j1 (entre 6 à 15 heures après ing[r] ...
4
Role of Estrogen Receptors in Male Reproductive Physiology
... both receptors involves six functional do- mains denoted A-F (O’Donnell et ...estrogen receptors is the most highly con- served region, implicating its importance in functional val- ue, and it contains the ...
6
Deciphering the language of fungal pathogen recognition receptors
... recognition receptors must adapt quickly to varied and modulating ...of receptors, which adapt to ever-changing pathogen-specific invasion markers thanks to their repeat-based architecture, which can ...
2
Macrocyclic Hamilton-type Receptors Comprising a Ferrocene Pivot
... Hamilton-type Receptors Comprising a Ferrocene Pivot Synthetic hydrogen-bonding receptors are described, which incorporate a central electroactive ferrocene moiety grafted with two adjacent ...
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Deciphering the language of fungal pathogen recognition receptors
... of receptors plays a key role in the innate immune system of animals, plants and ...recognition receptors can provide insight into the molecular mechanisms of immune response and describe the limits of the ...
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