murine model
![Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model
... toxic effects of BaP have been extensively characterized 9,10 . However, the impact of BaP on the intestinal BCC is still unknown. Based on its pro-inflammatory and mutagenic proprieties, we hypothesized that oral ...
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CpG-ODN and MPLA Prevent Mortality in a Murine Model of Post-Hemorrhage-Staphyloccocus aureus Pneumonia
... Found at: doi:10.1371/journal.pone.0013228.s002 (3.00 MB TIF) Figure S3 Evolution of histological findings following sepsis onset. Four groups of mice were studied (each group, n = 3): naive, sham-treated (S), ...
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The anti-inflammatory properties of intravenous immunoglobulin in a murine model of allergic airway disease ; effects on the development of regulatory T-cells
... The receptor that IVIg interacts with to induce tolerogenic DC populations is unknown. Previous work with IVIg suggests that FcγR are important for the anti-inflammatory action in ITP. Prime candidates for the mediating ...
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Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis
... the murine model of bleomycin (BLM)-induced pulmonary fibrosis and chronic treatment with an anti-MIF antibody was reported to have a beneficial effect on lung inflammation in the acute phase, which is the ...
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Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model.
... Florence Ader 1,2*† , Samir Jawhara 3† , Saad Nseir 4 , Eric Kipnis 5 , Karine Faure 5 , Fanny Vuotto 5 , Chanez Chemani 5 , Boualem Sendid 3 , Daniel Poulain 3 and Benoit Guery 5 Abstract Introduction: Pseudomonas ...
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[18F]Fludarabine-PET in a murine model of multiple myeloma
... Discussions Recently, [ 18 F]fludarabine has been introduced as an innovative PET radiotracer for imaging lymphoma, which demonstrates great potential for accurate imaging of lymphoproliferative disorders. This ...
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Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury.
... PDOC murine model is a good model to evaluate stem cell survival and presence in injured airway but stem cell differentiation into airway epithelial cells is unlikely at this ...PDOC model may ...
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The effect of dietary fatty acids on bone marrow fat in a murine model of senile osteoporosis
... AIM: To analyse the changes in bone parameters and fat distribution induced by different dietary fatty acids in a murine model of senile osteoporosis. METHODS: Two-month-old senescence accelerated P8 ...
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The synergistic effects of sulfated lactosyl archaeol archaeosomes when combined with different adjuvants in a murine model
... Pharmaceutics 2021, 13, 205 2 of 14 Archaeosomes are a type of liposome traditionally comprised of total polar lipids (TPL) or semi-synthetic glycerolipids of ether-linked isoprenoid phytanyl cores with varied glyco- ...
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Contribution to the study of the pathogenesis of dermatophytosis using a murine model of infection with Arthroderma benhamiae
... Corresponding author: mpheinen@ulg.ac.be Dermatophytoses are common zoonotic skin diseases whose immunology remains largely unknown, which could explain the failure of most vaccination assays against them. Despite their ...
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Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy
... In our electrophysiological measurements of synaptic readouts, we observed that selenate significantly increased basal synaptic transmission in Tg, as becoming overt in the input-output curves. Furthermore, we recorded ...
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Anti-VEGFA therapy reduces tumor growth and extends survival in a murine model of ovarian granulosa cell tumor
... !!!" " Abstract Ovarian granulosa cell tumors (GCTs) are potentially malignant tumors that have a tendency for late recurrence and cause death in 80% of women with advanced GCT due to recurrent disease. Although ...
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The synergistic effects of sulfated lactosyl archaeol archaeosomes when combined with different adjuvants in a murine model
... Mice were immunized with OVA antigen alone or formulated with SLA archaeosomes, other adjuvants (Poly(I:C), R848, CpG, MPLA, QS-21 and Pam 3 CSK 4 ) or SLA in combination with other ad[r] ...
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Uncaria guianensis (Aubl.) J.F. Gmel. extracts reduce bronchial hyper responsiveness and inflammation in a murine model of asthma
... Uncaria guianensis (Aubl. ) J. F. Gmel. (“cat’s claw”, Rubiaceae) is a plant with potential to treat asthma because of its anti-inflammatory and antioxidant activities. The aim of this study was to evaluate the effects ...
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B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia
... Our combined data provide the first demonstration of successful ex vivo LV gene therapy in an animal model of XLA. Transplanta- tion of E B29-Btk-LV–transduced Lin ⫺ BM into lethally irradi- ated recipients led ...
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The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis
... License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ABSTRACT Purpose: Marrow adipose tissue (MAT) expansion and ...
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Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.
... an ECM model is required and should involve microarray analyses on the brain and cytokine assays. However, effects of AVA + MQ were only evaluated in a prophylactic strat- egy and not in a treatment strategy. This ...
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Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction
... force–frequency responses were analyzed using the Kruskal- Wallis test taking into account the return to the baseline between each force measure. Differences in muscle contrac- tility for fatigability between groups were ...
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Potential therapeutic target in a murine model of eosinophilic airway inflammation
... ADAM28 is overexpressed in sputum cells form asthma patients and could play a key role in the remodeling of the airway following eosinophilic inflammation. Further investigations are n[r] ...
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Identifying PGC-1α-dependent hepatokines in a non-alcoholic fatty liver disease murine model
... in murine livers combined with an obesogenic diet, can we expect the same outcome if mice are changed to CHOW control diet after 6 weeks? This interesting question highlights how metabolic challenges may trigger ...
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