Multiple sclerosis (MS)
Working memory impairments in Multiple Sclerosis: effects on stress clash resolution.
... 2.1.1. Multiple sclerosis group (MS) MS patients meeting with a clinically definite relapsing- remitting form of multiple sclerosis ...
5
A robust Expectation-Maximization algorithm for Multiple Sclerosis lesion segmentation
... Abstract A fully automatic workflow for Multiple Sclerosis (MS) lesion segmentation is described. Fully auto- matic means that no user interaction is performed in any of the steps and that all parameters ...
10
Can Enhancing Neuronal Activity Improve Myelin Repair in Multiple Sclerosis?
... Despite the limited regenerative capacity of the CNS, myelin repair, or remyelination, can occur spontaneously in demyelinating diseases such as multiple sclerosis (MS). The most accepted mechanism of ...
10
Gender and sex hormones in multiple sclerosis pathology and therapy.
... Neuronal damage is an important issue in multiple sclerosis and correlates best with persisting disability. Axonal and dendritic damage is detectable from early clinical stages, and is associated with ...
30
Multiple Sclerosis Lesions Evolution in Patients with Clinically Isolated Syndrome
... shows different spatio-temporal patterns of enhancement compared to the traditional Gadolinium (Gd) due to its nature of highlighting macrophages 4 . The MS onset can be studied on CIS patients, which are patients who ...
9
Oligodendrocyte Development and Regenerative Therapeutics in Multiple Sclerosis
... 3. Toward Remyelination and Repair in Multiple Sclerosis (MS) 3.1. MS: Clinical Forms and Pathological Features of the Lesions MS is the most frequent chronic inflammatory disease associated with CNS ...
16
Remyelination in multiple sclerosis: from basic science to clinical translation
... 5-2) Update on clinical trials targeting myelin regeneration in MS We interrogated two clinical trials registers: “clinical trial.gov” and “EU clinical trial register” excluding phase 1 studies and studies for which the ...
34
Multiple Sclerosis lesion segmentation using an automatic multimodal Graph Cuts: Multiple Sclerosis lesion segmentation using an automatic multimodal Graph Cuts
... 4 Montreal Neurological Institute, McGill University, Montreal, Canada Abstract. Graph Cuts have been shown as a powerful interactive seg- mentation technique in several medical domains. We propose to automate the Graph ...
10
Autobiographical memory facilitation in multiple sclerosis: a neuropsychological and neuroimaging approach
... B ackground and aims: In a clinical-first study, we showed an autobiograph- ical memory (AbM) impairment in non-depressed multiple sclerosis (MS) patients. Data suggested an access deficit. On this basis, a ...
1
The NOD-like receptors as endogenous inhibitors of multiple sclerosis
... 5N4 Multiple sclerosis (MS) is a chronic disease of the CNS, manifested by relapses in the early phase followed by progressive disability in the later ...
161
B cell differentiation is defective in Multiple Sclerosis patients
... Clinical trials on the efficacy of B-cell depleting therapies in relapsing multiple sclerosis (MS) have suggested that B cells may contribute to MS pathogenesis, potentially through antibody independent ...
2
Activation-induced cell death in T lymphocytes from multiple sclerosis patients.
... Introduction Multiple sclerosis (MS) is an autoimmune disease affecting the cen- tral nervous system and a leading cause of neurological disability in young ...
5
Classification of Multiple Sclerosis Lesions using Adaptive Dictionary Learning
... c CNRS, IRISA, UMR 6074, F-35042 Rennes, France d Inria, VISAGES Project-team, F-35042 Rennes, France Abstract This paper presents a sparse representation and an adaptive dictionary learning based method for automated ...
18
Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis
... in Multiple Sclerosis Justin Killick 1,2 , Joanne Hay 1,2 , Elena Morandi 3 , Sonja Vermeren 1 , Saniya Kari 3 , Thibault Angles 3 , Anna Williams 2,4 , Jan Damoiseaux 5 and Anne ...
17
Dynamic imaging of individual remyelination profiles in multiple sclerosis
... Figure Legends Figure 1: Representative MRI and PET images from MS patients A-D. T1-weighted MRI (A), T2-weighted MRI (B), [ 11 C]PIB standard uptake value (SUV) map (C), and [ 11 C]PIB distribution volume ratio (DVR) ...
51
Automatic graph cut segmentation of multiple sclerosis lesions
... Index Terms— Graph Cut, Expectation-Maximization, multiple sclerosis, tissue classification 1. INTRODUCTION Manual and semi-automatic segmentation methods are very time consuming and can show a high ...
3
MRI predictors of cognitive outcome in early multiple sclerosis.
... Keywords Multiple sclerosis ; Brain atrophy ; Ventricular fraction ; Cognition ; Magnetic resonance ...of Multiple Sclerosis (MS) and may affect everyday ...
9
Involvement of CD8+ T Cells in Multiple Sclerosis
... Keywords: multiple sclerosis, autoimmunity, CD8 + T cells iNTRODUCTiON Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), resulting in ...
10
Imaging biomarkers in Multiple Sclerosis: from image analysis to population imaging
... 3. Image processing in Multiple Sclerosis 3.1. Context Today, measures from MRI complement and enrich the clinical observations based on scales such as the expanded disability status scale (EDSS) or the MS ...
14
Automatic Segmentation of Intramedullary Multiple Sclerosis Lesions
... ABSTRACT Context: The spinal cord is a key component of the central nervous system, which contains neurons responsible for complex functions, and ensures the conduction of motor and sensory information between the brain ...
139