Mucosal Innate and Adaptive Immunity
AID and APOBECs span the gap between innate and adaptive immunity
... CSR and, as a result, is critical for the generation of B cells that secrete Abs with various effector functions and tissue distribution in the organ- ism ( Muramatsu et ...mucosa and can be ...
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Mucosal immunity in Toxoplasma gondii infection
... macrophages and dendritic cells produced ...between innate and adaptive ...IL-2 and exhibits stimulatory effects on T cell pro- ...effects and as most relevant to this review a ...
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Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut
... intestinal innate immunity (Figure 1). It creates physical and chemical barriers that protect the host (Peterson and Artis, ...cells, and Paneth cells, all of which are derived from a ...
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Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts
... liver immunity; innate immunity; viral escape; immune therapeutic concepts ...Liver Innate Immunity in Pathogen Clearance and Immune-Driven Pathogenesis: Generalities The liver, ...
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Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity
... IgA and that IL-21 can cooperate with TGF β and retinoic acid to induce IgA class-switch recombination in ...cell and T cell responses in the intestine of mice with different intestinal ...(SFB) ...
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Dendritic Cells: More Than Just Adaptive Immunity Inducers?
... - and express NK markers such as ...NK1.1 and NKG2D. They produce large amounts of type I IFN, IFN and IL12 and may kill cells lacking self-major histo- compatibility complex molecules in a ...
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Mixed mucosal-parenteral immunizations with the broadly conserved pathogenic Escherichia coli antigen SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota
... SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota Ilham Naili, Juliette Vinot, Barbara Baudner, Annick Bernalier-Donadille,. Mariagraz[r] ...
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Mixed mucosal-parenteral immunizations with the broadly conserved pathogenic Escherichia coli antigen SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota
... SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota Ilham Naili, Juliette Vinot, Barbara Baudner, Annick Bernalier-Donadille,. Mariagraz[r] ...
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Mesenchymal Stem Cells Regulate the Innate and Adaptive Immune Responses Dampening Arthritis Progression
... proliferation and differentiation to plasma cells as well as antibody production have been described, the capacities to induce the survival and stimulate proliferation and differentiation of various ...
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The nuclear pore complex and its transporters : from virus-host interactors to subverting the innate antiviral immunity
... import and export, as it exports Kapα adaptors for the formation of import complexes [26], also reduces the innate antiviral ...export and has been shown to associate with DDX3X for nuclear export in ...
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E3 ubiquitin-ligases and their target proteins during the regulation of plant innate immunity.
... with and down-regulates the accumulation of the NB-LRR R proteins Suppressor of npr1-1 Constitutive1 (SNC1) and Resistant to ...SNC1 and RPS4, an addi- tional NB-LRR immune receptor, are also ...
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Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice.
... types and can influence local immune ...clinical and pathological features of MS ...inflammatory and autoimmune responses against the MOG35–55 peptide were ...
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View of Innate immunity — Targeting of host cell chromatin by bacteria: what are the implications for innate immune response?
... L ’identification récente de facteurs de virulence bactériens capables de se localiser dans le noyau de la cellule hôte et de modifier la structure de la chromatine indique que les bacté[r] ...
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Genes of innate immunity and their significance in evolutionary ecology of free livings rodents
... by innate immunity Pattern Recognition Receptors (PRRs) is crucial in this process ...parasitic and viral nucleic acids) ...mice and poultry ...biologists and ecologists since JBS ...
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Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease
... Chemokines, and Acute-Phase ...manufacturer and contained the following targets: IL-1β, IL- 1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12(p70), IL-13, IL-15, IL-17, Basic FGF, Eotaxin, G-CSF, ...
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Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis
... studies and experimental ...manifestations and often fail to develop disseminated intravascular ...handle and process clinical samples are ...markers, and gave conflicting ...cases and ...
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Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development
... spleen, and BM (Figure ...phenotypic and functional diversity of TANs in ...markers and cell surface receptors on live CD45+Ly6G+ neutrophils at a single-cell level by flow ...skin, and tumor) ...
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Activation of innate immunity by 14-3-3 ε, a new potential alarmin in osteoarthritis
... deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private research ...
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Activation of innate immunity by lysozyme fibrils is critically dependent on cross-β sheet structure.
... structural and immunological data, clearly demonstrates that lysozyme fibrils are immunologically active species, and strongly sug- gests that their cross-β sheet structure is critical for driving ...
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Innate immunity genes as determinants of resistance/susceptibility to human disease : studies in leukemia patients
... (CLL) and myeloid leukemias (CML) in the Belgian ...functional and mutant variants of the KIR2DS4 ...Polish and German individuals discriminated between functional KIR2DS4 and its mutant ...
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