mRNA decay
Conceptual Modeling of mRNA Decay Provokes New Hypotheses
... some mRNA decay factors are associated with both full length mRNA and its degradation ...length mRNA was different in different experiments (it is highly sensitive to the strain background and ...
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The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.
... in mRNA decay and splicing. Although we focused our attention on mRNA decay, our results suggest that ERG proteins might achieve control of gene expression by orchestrating multiple processes ...
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The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD)
... RNA decay pathway called nonsense-mediated mRNA decay (NMD), which can target multiple viral RNAs, including HTLV-1 unspliced RNA, as has been recently ...on mRNA organization and the ...
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The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1
... the mRNA decay machinery TTP has been reported to activate both 3′→5′ mRNA decay, by recruiting the multi- subunit Ccr4-Not deadenylase complex to the mRNA, and 5′→3′ mRNA ...
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GC content shapes mRNA decay and storage in human cells
... on mRNA decay and translation depending on their GC content In human, the DDX6 RNA helicase is key for PB assembly ...in mRNA translation repression and decapping [6,7], suggesting that it plays a ...
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Premature termination codons in SOD1 causing Amyotrophic Lateral Sclerosis are predicted to escape the nonsense-mediated mRNA decay
... identified. mRNA harboring PTCs are known to be rapidly degraded by nonsense‑mediated mRNA decay (NMD), which limits the production of truncated ...in mRNA, we analyzed the localization of ...
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Mechanistic insights of SIDER2 retroposon-mediated mRNA decay in Leishmania
... in mRNA decay, the 3'UTRs of the ...their decay rates were ...their decay did not involve prior-shortening of the poly(A) tail ...Deadenylation-independent mRNA decay was ...
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Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes
... of mRNA levels was observed when the list of uORFs was restricted to those having an initiator AUG codon in the optimal Kozak context ( ...allow mRNA to escape NMD in the case of either AUG-proximal ...
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Identification d’inhibiteurs du nonsense-mediated mRNA decay (NMD) et utilisation comme approche thérapeutique dans certaines maladies génétiques
... De plus, une étude chez la levure a montré que le decapping de l’ARNm peut être initié de façon co-traductionnelle lorsqu’il est encore associé au ribosome dans les fractions polysomal[r] ...
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Composition et dynamique des complexes protéiques impliqués dans le "nonsense-mediated mRNA decay" chez la levure Saccharomyces cerevisiae
... To establish how NMD4 and EBS1 could affect NMD substrates, we searched for conditions that would simplify our phenotypic analysis. We chose to focus on the helicase and C- terminal domain of Upf1, important for binding ...
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GC content shapes mRNA storage and decay in human cells
... in mRNA decay ( Vindry et ...between mRNA stabilization after PAT1B and after DDX6 silencing (r s = ...XRN1 decay targets, PAT1B targets tended to be AU-rich (r s = ...5’ decay ( Figure ...
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ALS-associated RNA-binding protein FUS and mRNA translation regulation
... I also decided to use HEK293T cells because they are a well characterized human cell line and are great to study mRNA translation. Indeed, translation is always active in those cells with strong protein synthesis ...
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Absence of aromatase protein and mRNA expression in endometriosis.
... stopping mRNA amplification at 40 cycles, and included additional controls (analysis of mRNA quality, sequencing of amplification products, standard curve analysis with dilutions of plasmid constructions and ...
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CUORE sensitivity to 0νββ decay
... – E represents the data. It is a list of N energy bins cen- tered at the energy E i and containing n i event counts. The energy range is [2470; 2570] keV. This is the same range used for the CUORE-0 0 νββ decay ...
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CUORE sensitivity to 0νββ decay
... – E represents the data. It is a list of N energy bins cen- tered at the energy E i and containing n i event counts. The energy range is [2470; 2570] keV. This is the same range used for the CUORE-0 0 νββ decay ...
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The mRNA transportome of the BicD/Egl transport machinery
... RT-PCR and RT-qPCR analysis The RNA from each IP was resuspended in 25 ml of DEPC treated water and its quality was analyzed with the Eukaryote Total RNA Nano chip in an Agilent bioanalyzer. RT-PCR assays were performed ...
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Angular analysis of the decay
... the decay rate for the B þ → K þ μ þ μ − process: the forward-backward asymmetry A FB of the dimuon system and the contribution F H from the pseudoscalar, scalar, and tensor amplitudes to the decay ...the ...
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Exponential decay of scattering coefficients
... coefficients decay exponentially as a function of their order, which suggests that further analyses could focus on understanding better the low-order coefficients, while neglecting the high-order ...
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mRNA maturation in giant viruses: variation on a theme
... mimiviruses mRNA capping enzyme, we wondered whether the Mg18, like its Vaccinia virus VP39 homologue, could retain the 2 O MTase activity (Supplementary Figure S1C, step ...
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Nucleotide sequence of hamster glyceraldehyde-3-phosphate dehydrogenase mRNA
... The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.. L’archive ouverte pluridisciplinaire HAL, est destinée au[r] ...
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