Mononuclear phagocytes
Subretinal mononuclear phagocytes induce cone segment loss via IL-1β
... free condition, in a 12 hr/12 hr light/dark (100–500 lux) cycle with water and normal diet food avail- able ad libitum. All experimental protocols and procedures were approved by the local animal care ethics committee (N ...
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Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow
... Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid derived suppressor cells from human blood and bone marrow.. Mikael Roussel, *,†,‡,§,1 P.[r] ...
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en fr Upregulation od P2RX7 in CX3CR1 deficient mononuclear phagocytes leads to increased IL-1β secretion and photoreceptor neurodegeneration L'invalidation de CX3CR1 induit une surexpression de P2RX7 dans les phagocytes mononucléés responsable de l'augmentation de la sécrétion d'IL-1β et de la mort des photorécepteurs.
... On distingue deux formes avancées: la forme humide, néovasculaire ou encore exsudative présentant des néovascularisations choroïdiennes (Figure. 11C et 13C) et la forme sèche ou atro[r] ...
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en fr Implication of mononuclear phagocytes in chronique inflammatory disorders : investigation of a atherosclerotic mouse model and the xanthogranuloma in humans Implication des phagocytes mononucléés dans les pathologies inflammatoires chroniques : exploration d'un modèle murin d'athérosclérose et du xanthogranulome chez l'homme
... des phagocytes mononucléés dans les maladies immuno-inflammatoires chroniques avec pour support un modèle murin d’athérosclérose ainsi que l’exploration d’une pathologie humaine, le ...
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Transcriptional regulation of mononuclear phagocyte development
... France Mononuclear phagocytes (MP) are a quite unique subset of hematopoietic cells, which comprise dendritic cells (DC), monocytes as well as monocyte-derived and tissue-res- ident ...
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Defining Mononuclear Phagocyte Subset Homology Across Several Distant Warm-Blooded Vertebrates Through Comparative Transcriptomics
... The mononuclear phagocytes encompass three main functional cell types: monocytes (Mo), macrophages (MP), and ...these mononuclear phagocyte category encompasses a complex array of different subtypes ...
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Editorial: The Mononuclear Phagocyte System in Infectious Disease
... Lugo-Villarino et al. The Mononuclear Phagocytes in Infection better define MPS functional properties that can be exploited for therapeutic and vaccination purposes. With regard to animal models, the ...
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Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry
... 22. Krieg C, Nowicka M, Guglietta S et al. (2018) High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy. Nat Med 9:2579–2514. 10.1038/nm.4466 23. Roussel M, Ferrell PB, Greenplate AR et al. ...
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Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration
... Mononuclear phagocytes (MP) comprise a family of cells that include microglial cells (MC), monocytes (Mo), and macrophages (M/) among others (Chow et al, ...
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Thermal spin-crossover with a large hysteresis spanning room temperature in a mononuclear complex.
... However, known SCO compounds showing hysteresis are probably only a few tenths so far. When focusing on large hysteresis spanning room temperature, this number decreases to a few units almost always belonging to the ...
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Mononuclear copper(II) complexes containing a macrocyclic ditopic ligand: synthesis, structures and properties
... 4. Conclusions In summary, we have reported here the synthesis and characterization of three new mononuclear copper(II) complexes 1-3 bearing ditopic macrocyclic ligands (L 1 or L 2 ). The solid state studies for ...
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The role of ligand design affecting the thermal and light-induced spin transition in mononuclear iron(II) complexes
... *Corresponding Author: Prof. Chérif Baldé Laboratoire de Chimie et Physique des Matériaux (LCPM), Université Assane Seck de Ziguinchor, Bp: 523 Ziguinchor, Sénégal. ABSTRACT Molecules are increasingly considered for ...
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Tacrolimus diffusion across the peripheral mononuclear blood cell membrane impact of drug transporters
... inhibition of the CaN activity; FKBP: FK Binding Protein INTRODUCTION Tacrolimus (TAC) is the main immunosuppressive drug prescribed in solid organ transplant patients. Its effect is mediated through the inhibition of ...
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Antigen-Specific Gene Expression Profiles of Peripheral Blood Mononuclear Cells Do Not Reflect Those of T-Lymphocyte Subsets
... and DNA Array Unit, National Institute on Aging, Bethesda, Maryland 4 Received 23 April 2004/Returned for modification 28 June 2004/Accepted 1 July 2004 Advances in microarray technology have allowed for the monitoring ...
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Transcriptome Analysis Describing New Immunity and Defense Genes in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients
... Methodology/Principal Findings: The Illumina Human-6v2 Expression BeadChips were used for a complete genome-wide transcript profiling of peripheral blood mononuclear cells (PBMCs) from 18 RA patients and 15 ...
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Characterization of adenosine A 2 receptors of peripheral blood mononuclear cells of patients with fibromuscular dysplasia
... blood mononuclear cells (PBMCs) PBMCs were chosen because the pharmacological profile of adenosine receptors expressed at their surface mirrors that of their counterparts associated with cardiovascular tissues 8 ...
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Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy
... Autophagy plays an important role in the regulation of autoimmune and autoinflammatory responses of the immune cells. Defective autophagy process is associated with various autoimmune and inflammatory diseases. Moreover, ...
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Cryopreservation of mononuclear cells before extracorporeal photochemotherapy does not impair their anti-proliferative capabilities
... Universit é d ’ Auvergne, Clermont-Ferrand, France, and 6 EFS Rh ô ne-Alpes, La Tronche, France Abstract Background aims. The clinical benefi ts of extracorporeal photochemotherapy (ECP) are well recognized, but its ...
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Bovine Viral Diarrhoea Virus Induces Apoptosis in Blood Mononuclear Cells by a Mechanism Largely Dependent on Monocytes
... Davis, W. C., Brown, W. C., Hamilton, M. J., Wyatt, C. R., Orden, J. A., Khalid, A. M. & Naessens, J. (1996). Analysis of monoclonal antibodies specific for the gd TcR. Veterinary Immunology and Immunopathology 52, ...
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Fine Control of the Metal Environment within Dysprosium-Based Mononuclear Single-Molecule Magnets
... and first excited state and the evaluated experimental energy barrier. Conclusions In conclusions, four new Dy(III)-based complexes, three mononuclear ones and one chain system, have been synthesized using the ...
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