Molecular imaging
Development of Targeted Microbubbles for Ultrasound Molecular Imaging of Breast Cancer
... analyzed. Molecular imaging with ultrasound (US) is able to detect the expression of a specific protein when using targeted contrast ...US molecular imaging approach using microbubbles (MB) ...
3
Molecular Imaging in Tissue and Cells by Computer-assisted Innovative Multiomode Mass Spectrometry: COMPUTIS, a new European Project
... actual molecular image of flat samples with a full mass spectrometry at each pixel down to micrometric ...for Molecular Imaging Mass Spectrometry (MIMS), enabling innovative approaches in functional ...
2
Kinetic analysis of novel mono- and multivalent VHH-fragments and their application for molecular imaging of brain tumors
... tyrosine kinase domain resulting in a ligand-independent receptor (Wikstrand et al., 1998). The appearance of EGFRvIII is associated with poor tumour prognosis (Shinojima et al., 2003). The EGFR and EGFRvIII have been ...
20
Magnetosomes used as biogenic MRI contrast agent for molecular imaging of glioblastoma model
... for molecular imaging of glioblastoma model This PhD thesis focuses on the study of a new class of contrast agent for MRI, the magne- tosomes, which are natural iron-oxide vesicles produced by magnetotactic ...
197
Application of aptamers for in vivo Molecular Imaging and Theranostics
... these imaging probes in vivo requires further ...high molecular weight molecules that can reduce the renal ...the imaging probe with that of one comprised of a random sequence of the same size and ...
40
Molecular imaging of the human pulmonary vascular endothelium using an adrenomedullin receptor ligand
... human albumin. Another limitation is that approximately 350,000 particles of this tracer are injected and block as many pulmonary vessels in the process. This undesirable ‘‘physical’’ blockage of pulmonary circulation in ...
13
Brain molecular imaging in pharmacoresistant focal epilepsy: Current practice and perspectives
... brain molecular imaging, ...SPECT imaging is able to measure regional cerebral blood flow and its major originality remains its ictal imaging ...
35
Comparison of T2 and T2 *-weighted MR molecular imaging of a mouse model of glioma
... for molecular imaging in animal models of gliomas have not been yet fully ...weighted imaging (SWI) in T2 and T2* contrast-enhanced molecular MRI of ...MR imaging was performed on the ...
9
en fr Smart agents for molecular imaging Des agents intelligents pour l’imagerie moléculaire
... resonance imaging contrast ...on molecular imaging probes which hold the promise of MRI visualization of different biomarkers and tissue physiological ...the molecular structure to produce a ...
17
Multimodal molecular imaging of atherosclerosis: Nanoparticles functionalized with scFv fragments of an anti-αIIbβ3 antibody
... atherosclerosis, molecular imaging based on the targeting of specific markers would substantiate the diagnosis of life threatening atheroma ...resonance imaging of the atheroma plaque were performed ...
13
Conception and synthesis of the new cryptophane for the applications in xenon NMR molecular imaging
... In this context, the objective of this thesis is to design new cryptophanes which can be used as molecular platforms for constructing new 129 Xe MRI biosensors usable for in vivo MRI molecular ...
251
Pre-clinical and clinical evaluation of nuclear tracers for the molecular imaging of vulnerable atherosclerosis: an overview.
... technique. Imaging modalities such as intravascular ultrasound or optical coherence tomography are currently being evaluated for vulnerable plaque detection [10 ] ...non-invasive molecular imaging ...
15
Ultrasound Molecular Imaging: How to develop clinical products?
... It has been proposed to exploit the specific property of UCA as strict vascular bed marker to be used for molecular imaging when targeting receptors or proteins of interest are expressed at endothelial ...
4
PET molecular imaging of peripheral and central inflammatory processes targeting the TSPO 18 kDa
... not be signi ficant due to the fact that in human, [ 18 F]DPA- 714 is also largely eliminated by the hepatic pathway but with high gall bladder accumulation limiting the radioactiv- ity signal in the intestine. In rats, ...
197
Comparison of T₂ and T₂ *-weighted MR molecular imaging of a mouse model of glioma
... for molecular imaging in animal models of gliomas have not been yet fully ...weighted imaging (SWI) in T2 and T2* contrast-enhanced molecular MRI of ...MR imaging was performed on the ...
9
Elemental and molecular imaging of human full thickness skin after exposure to heavy metals
... Biopsies of human skin were embedded in a Tissue-Tek OCT (Sakura Finetek USA, Inc.), frozen in liquid nitrogen and stored at -80°C. Sections of 10 µm were cut on a cryostat, placed on Superfrost+, mounted on slides ...
9
Contribution of high mass resolution and accuracy of FTMS to molecular imaging
... 2. IDENTIFICATION METHODS IMPLEMENTED IN IMS High molecular weight compounds Shimma,S. et al. Surf. Interface Sci. 2006, 38(12-13), 1712 Groseclose, M.R. et al. J. Mass Spectrom. 2007, 42(2), 254 Chughtai, K. and ...
34
Ultrafast Molecular Imaging by Laser Induced Electron Diffraction
... the molecular structure from the photo-electron spectra of a laser-driven linear, symmetric ...symmetric molecular system for which the HOMO, or any molecular orbital contributing to the ionization ...
5
Gd(III) polyaminocarboxylate chelate: realistic manybody molecular dynamics simulations for molecular imaging applications
... Owing to its high spin S of 7/2, the f 7 gadolinium (III) ion is widely used in magnetic resonance imaging (MRI) to enhance image contrast. The imaging is based on 1 H NMR of the aqueous protons in the ...
14
en fr Characterization and Molecular Imaging and Atherosclerotic Plaque : Preclinical Studies Caractérisation et imagerie moléculaire de la plaque d'athérome : études pré-cliniques
... dans du sang humain a montré des résultats analogues à ceux obtenus par l’étude in vitro réalisée dans le sang de souris, tant en termes de stabilité dans la fraction libre du plasma qu'[r] ...
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