Metastatic Head and Neck Carcinoma
Cetuximab combined with paclitaxel or paclitaxel alone for patients with recurrent or metastatic head and neck squamous cell carcinoma progressing after EXTREME
... MATERIALS AND METHODS 2.1 | Study design and data source We retrospectively collected the medical files of all patients treated with paclitaxel +/- cetuximab in seven French centers between January 2010 ...
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AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity
... AKT1 and AKT2 iso- forms in both the ErbB2-driven and the polyoma middle T (PyMT)-driven mammary adenocarcinoma transgenic mouse models [ 26 , 27 , 37 ...of metastatic lesions [ 27 ...AKT1 and ...
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DNA damage response- and JAK-dependent regulation of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) cells exposed to 5-fluorouracil (5-FU)
... Response- and JAK- dependent induction of PD-L1 by 5-FU in HNSCC ...context and is potentially therapeutically actionable. Introduction Head and Neck Squamous Cell Carcinoma ...
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Preferential Response of Basal-Like Head and Neck Squamous Cell Carcinoma Cell Lines to EGFR-Targeted Therapy Depending on EREG-Driven Oncogenic Addiction
... cells, and reduced their clonogenic ...EREG and AREG expression may be ...EREG and AREG, and that AREG and EREG ...expression and response to Cetuximab using a collection of ...
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Impact of Neck Dissection in Head and Neck Squamous Cell Carcinomas of Unknown Primary
... ] and international NCCN ...study and systematically after the publication of the PET-neck study [ 16 ...mucosal carcinoma of the upper aerodigestive tract and regional relapse as nodal ...
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Effects of proton versus photon irradiation on (lymph) angiogenic, inflammatory, proliferative and anti-tumor immune responses in head and neck squamous cell carcinoma
... cells and that TRF2 over-expression had a negative impact on patients ’ ...P, and con firmed the X radiation-induced PD-L1 expression in other ...metastasis and poor prognosis, being an independent ...
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Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer
... radiotherapy and in some ways it is significantly more complex, requiring specialized software ...neutrons and photons through the patient ’s geometry and uses track-length density estimators of ...
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Episomal HPV16 responsible for aggressive and deadly metastatic anal squamous cell carcinoma evidenced in peripheral blood
... cell carcinoma with vertebral HPV16–positive metastasis were retrospectively analyzed by the Capture‑HPV method (Capt‑HPV) followed by Next‑Generation Sequencing ...initial and second anal biopsy samples, ...
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Framing body changes in patient-medical team conversations during treatment trajectories in surgical head and neck oncology
... care and the collaborative process through which doctors and patients express and negotiate their perspectives and priorities (Thoër, ...“physician and patient, with various levels of ...
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Role of near-infrared fluorescence imaging in head and neck cancer surgery: from animal models to humans
... light and re-emit light of a longer wavelength after a brief interval of ...700 and 900 ...levels and depth of endogenous fluorophores can be present in cancer-induced biochemical changes, such as ...
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Searching beyond the usual papillomavirus suspects in squamous carcinomas of the vulva, penis and head and neck
... designed and constructed for the assessment of the HPV contribution to a number of anogenital and HN human tumors (Alemany et ...protocols and results for cervical (de Sanjose et ...2016) and ...
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Predictive factors of toxicity of TPF induction chemotherapy for locally advanced head and neck cancers
... Deaths related to induction chemotherapy There were 6% deaths (n = 7) during TPF induction chemotherapy (3/44 for laryngeal preservation patients, and 4/69 for inoperable patients). Five occurred after the first ...
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The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications.
... In 2000, Bonner et al demonstrated in a pannel of SCCHN cell lines that the combination of cetuximab (5 µg/l) delivered simultaneously with radiation (3 Gy) resulted in a greater decrement in cellular proliferation than ...
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Altered expression pattern of circular RNAs in primary and metastatic sites of epithelial ovarian carcinoma
... destabilization and translational repression ...inhibition and hence have the potential to be used for RNA-based cancer therapies ...8mer and 7mer sites that match the seed region of human miRNA ...
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en fr The antitumor drug F14512 enhances cisplatin and ionizing radiation effects in head and neck squamous carcinoma cell lines Evaluation de combinaisons thérapeutiques ciblées en cancérologie des voies aérodigestives supérieures. Mise au point d’un modèle tumoral in vivo
... in head and neck cancer treatment protocols in Humans: cisplatin (CDDP) and ...F14512 and for each combination, the ED50, ED75 and ED90 values were calculated (Figure ...F14512 ...
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The impact of patients’ and physicians’ characteristics on surgery decision for head and neck cancer: Results of a national survey
... Head and Neck, CHU Toulouse, Toulouse, France; 2 University of Toulouse Paul Sabatier, Team Equity UMR 1027, Toulouse, France; 3 Registre des Cancers du Tarn, Centre Claudius-Regaud, Toulouse, ...
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Effect of modeling methods on the body and head-neck-trunck moments of inertia calculations in individuals of different morphology
... The author and co-authors if applicable retain copyright ownership and moral rights in this document. Neither the whole thesis or dissertation, nor substantial extracts from it, may be printed or otherwise ...
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The (head and neck) carcinologic handicap index: validation of a modular type questionnaire and its ability to prioritise patients’ needs
... Validation of the French Versions of the Speech Handicap Index and the Phonation Handicap Index in Patients Treated for Cancer of the Oral Cavity or Oropharynx. Folia Phoniatr Logop. 2019 ; 15: 1–14. ...
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Health professionals and the early detection of head and neck cancers: a population-based study in a high incidence area
... In France, Dentists examine around 500 000 mouths a day [22]; initially, it would thus seem an obvious strategy to entrust early detection of oral cavity cancers to these health professionals. However, our study shows ...
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The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer : a multicenter analysis.
... tumor and patient characteristics (such as tumor site, grade and stage), treatment policies, radiother- apy procedures and ¯ow cytometry ...values and variances for the cell kinetic parameters ...
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