• Aucun résultat trouvé

mdx Mice

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

... type mice (Fig ...young mdx mice, either treated or not with TSA, and transplanted into muscles of NOD/SCID mice together with MuSCs isolated from muscles of luciferase/GFP mice (Fig ...

15

Delayed cardiomyopathy in dystrophin deficient mdx mice relies on intrinsic glutathione resource.: Glutathione resource in mdx mice

Delayed cardiomyopathy in dystrophin deficient mdx mice relies on intrinsic glutathione resource.: Glutathione resource in mdx mice

... and mdx mice, 12, 13 and that of cardiomyopathy in mdx ...of mdx mice is counteracted by compensatory mechanisms involving up-regulation of glutathione cycle ...of mdx ...

37

Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice

Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice

... dystrophic mdx mice, at least in female mdx ...dystrophic mdx, we first performed echocardiographic measurements in treated mice in the first series of ...(Run+CLi-High) mdx ...

14

Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice

Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice

... Gabriela de Cássia Sousa Amancio, Andrea Grabe-Guimarães, Haikel Dridi, Johan Moreau, Neila Marcia Silva Barcellos, Alain Lacampagne, Stefan. Matecki, Olivier Cazorla[r] ...

9

Pathological pattern of Mdx mice diaphragm correlates with gradual expression of the short utrophin isoform Up71.

Pathological pattern of Mdx mice diaphragm correlates with gradual expression of the short utrophin isoform Up71.

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

2

The effect of respiratory muscle training with CO2 breathing on cellular adaptation of mdx mouse diaphragm.

The effect of respiratory muscle training with CO2 breathing on cellular adaptation of mdx mouse diaphragm.

... in mdx mouse diaphragm induced by specific training may help us to interpret the concomitant decrease in ...the mdx training group compared with the control ...the mdx mice was interpreted as ...

20

AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm

AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm

... the mdx diaphragm to a more oxidative ...untreated mice ( Figure 6 A). In AICAR-treated mdx mice, there was a small increase in type 1 (slow oxidative) fibers, but without any alteration in ...

11

Galectin-3 and N-acetylglucosamine promote myogenesis and improve skeletal muscle function in the mdx model of Duchenne muscular dystrophy

Galectin-3 and N-acetylglucosamine promote myogenesis and improve skeletal muscle function in the mdx model of Duchenne muscular dystrophy

... localizes exclusively in the inner cytoplasmic leaflet of membranes, is transiently exposed on the surface of the fusing membranes, and this transient exposure of PS is required for cell fusion (35). Interestingly, ...

23

Desmin prevents muscle wasting, exaggerated weakness and fragility, and fatigue in dystrophic mdx mouse

Desmin prevents muscle wasting, exaggerated weakness and fragility, and fatigue in dystrophic mdx mouse

... of mdx endogenous desmin is required, since mdx:desmin+/- mice do not exhibit severe dystrophic functional ...in mdx mice (Prins et ...in mdx mice induce severe dystrophic ...

48

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

... treated mdx mice with caffeine or dantrolene, two pharmacological agents known to increase or reduce calcium release by modulating RyR functions [35, ...in mdx mice ...in mdx ...

18

Effect of beta-dystroglycan processing on utrophin/Dp116 anchorage in normal and mdx mouse Schwann cell membrane.

Effect of beta-dystroglycan processing on utrophin/Dp116 anchorage in normal and mdx mouse Schwann cell membrane.

... and mdx mice were purchased from Jackson Laboratories ( Bar Harbor, ME ) and bred in our animal ...facilities. Mice were housed in plastic cages in a temperature-controlled environment with a 12-hour ...

32

alpha7B integrin changes in mdx mouse muscles after L-arginine administration.

alpha7B integrin changes in mdx mouse muscles after L-arginine administration.

... the mdx mouse strain exhibits a low but detectable nNOS level and activity ...5-week-old mdx mice was accompanied by a significant improvement in the histopathological appearance in the ...5-week-old ...

16

Ventilation during air breathing and in response to hypercapnia in 5 and 16 month-old mdx and C57 mice.

Ventilation during air breathing and in response to hypercapnia in 5 and 16 month-old mdx and C57 mice.

... the mdx mouse, which lacks dystrophin due to a nonsense point mutation in exon 23 of the Dystrophin gene (Sicinski et ...the mdx mouse show little fibrosis or functional alteration until late in life ...

19

Immunological characterization of dystrophin-deficient Dmd[mdx] rats

Immunological characterization of dystrophin-deficient Dmd[mdx] rats

... Conclusion 4 and 8 weeks and decreased at 12 weeks. Macrophages with M2 profiles represent the majority (>90%) of infiltrating immune cells and Teff cells were the majority of the remaining ones. We also analyzed ...

1

Ebola virus dynamics in mice treated with favipiravir

Ebola virus dynamics in mice treated with favipiravir

... The polymerase inhibitor favipiravir is a candidate for the treatment of Ebola virus disease. Here, we designed a mathematical model to characterize the viral dynamics in 20 mice experimentally infected with Ebola ...

17

Automated Home-Cage Behavioural Phenotyping of Mice

Automated Home-Cage Behavioural Phenotyping of Mice

... than the second group of annotators, which is in fact what we observed for our system. Table 1 also shows the comparison between the system and commercial software on the µfull database¶. Fig. 3 shows the confusion ...

28

Knowledge Discovery in Hepatitis C Virus Transgenic Mice

Knowledge Discovery in Hepatitis C Virus Transgenic Mice

... between genes and their functions based on expression profiles, and (iii) build diagnosis models for clinical classes, e.g. normal and diseased organs. With expression profiles from thousands of genes, the specific ...

13

Increased Atherosclerosis in Mice Deficient in Perilipin1.

Increased Atherosclerosis in Mice Deficient in Perilipin1.

... Ldlr-/- mice had comparable blood pressure and plasma lipids ...Ldlr-/- mice had a lower body weight and decreased ...Plin1-/-Ldlr-/- mice was moderately increased after 10 weeks of atherogenic diet ...

7

Inflammatory dendritic cells in mice and humans.

Inflammatory dendritic cells in mice and humans.

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

2

The Complex QT/RR Relationship in Mice

The Complex QT/RR Relationship in Mice

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

10

Show all 816 documents...

Sujets connexes