Matrix Metalloproteinases
HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway
... namely matrix metalloproteinases (MMPs), also releases growth factors sequestered by this network, increasing their chemoattractant potential by enzymatic cleavage [12, ...
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Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
... Vascular endothelial growth factor (VEGF) is the major endothelial mitogen in central nervous system neoplasms and it is expressed in 64-95% of glioblastomas (GBMs). Tumour cells are the main source of VEGF in GBMs ...
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Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases
... the matrix metalloproteinases (MMPs) MMP-2 and MMP-9 in comparison to typical lung cancer [12] ...extracellular matrix components, which play an important role in tumor growth and progression [13] ...
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VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: involvement of VEGFR-2, tissue type plasminogen activator and matrix metalloproteinases.
... fibrin matrix, we show that VEGF, an angiogenic cytokine that plays a crucial role in the onset of angiogenesis, is a potent activator of HUVEC-mediated ...or matrix metalloproteinases (MMP) ...
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Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension.
... of matrix metalloproteinases (MMP) expressed by human dermal fibroblasts submitted to mechanical stress relaxation by cytochalasin D (CD) and in a retracting collagen gel ...
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Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor
... In vivo, Ro-28-2653 reduced the growth of tumors induced by the inoculation of different cell lines producing MMPs and inhibited the tumor-promoting effect of fibroblasts on breast ade[r] ...
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Infrared optical imaging of matrix metalloproteinases (MMPs) up regulation following ischemia reperfusion is ameliorated by hypothermia
... Hypothermia attenuated both the optical increase in intensity after MMPSense750 and the increase in MMP-9 protein expression supporting the proof of concept that NIRF imaging using MMPSe[r] ...
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NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9.
... While a pathophysiological role of MMP-2 and MMP- 9 has been demonstrated in neuropathic pain, the rele- vance of these metalloproteinases in chronic inflamma- tory pain is still elusive. Our results show for the ...
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Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms.
... Tamarina, N.A., McMillan, W.D., Shively, V.P., Pearce, W.H., 1997. Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta. Surgery 122, 264 ]271. Tilson, M.D., Reilly, ...
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Emerging Roles of ADAM and ADAMTS Metalloproteinases in Cancer
... as matrix metalloproteinases (MMPs) and closely related ADAMs (a disintegrin and metalloproteinase) and ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) in cancer development and ...
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Role of ADAM and ADAMTS metalloproteinases in airway diseases
... And Metalloproteinases (ADAMs) and ADAMs with Thrombospondin motifs (ADAMTS) are proteinases closely related to Matrix Metalloproteinases ...extracellular matrix, growth factors or ...
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Matrix representations for toric parametrizations
... – One allows the use of quadratic syzygies (or higher-order syzygies) in addition to the linear syzygies in order to be able to construct square matrices. – One only uses linear syzygies as in the curve case and obtains ...
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Holomorphic anomaly and matrix models
... of matrix models, by using the requirement of modular invariance as in [1, 10], and shows that these couplings obey the equations of [6] that characterize topological string am- ...the matrix model free ...
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Reproducible and Accurate Matrix Multiplication
... By reproducibility, we mean getting a bit-wise identical floating-point result from multiple runs of the same code on the same data. Numerical reproducibility can be addressed by targeting either the order of operations ...
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Random Matrix Improved Subspace Clustering
... The central hypothesis of Assumption 2 is the choice of f 0 (2) = 0 without which kernel spectral clustering is asymptotically infeasible. Equipped with these intuitions, we are in position to introduce our main result ...
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Stochastic conditioning of matrix functions
... 6. Conclusions. We have defined a notion of stochastic condition number of a matrix function F to random noise H in its input. First we gave sufficient conditions for the first- order RMS approach from [ 21 , 6 ] ...
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Ultrasound Matrix Imaging. I. The focused reflection matrix and the F-factor
... matrix, the contributions of single and multiple scatter- ing and their impact on the resolution and contrast were carefully ...FR matrix paves the way towards a quantitative charac- terization of soft ...
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Crystallization of random matrix orbits
... In principle, all three operations can be expreseed in terms of multiplication, since for small ε, (1 + εAN )(1 + εBN ) ≈ 1 + ε(A N + BN ), thus reducing addition to multiplication (all three operations can be expressed ...
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Improving Maximum Margin Matrix Factorization
... 4. Srebro, N., Rennie, J., Jaakkola, T.: Maximum-margin matrix factorization. In Saul, L.K., Weiss, Y., Bottou, L., eds.: Advances in Neural Information Processing Systems 17, Cambridge, MA, MIT Press (2005) 5. ...
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A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
... Extracellular Matrix Microarray Seeding and Analysis Slides were washed in PBS and treated with UV prior to seeding cells. They were placed in a seeding device that holds the top surface of the slides flush with ...
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