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Lysyl Oxidase (LOX)

Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.

Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.

... the lysyl oxidase (LOX) precursor, the enzyme catalyzing the initial step in the formation of covalent collagen cross- links, an essential process for fibril ...

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Lysyl oxidase is a strong determinant of tumor cell colonization in bone. Short Title: LOX triggers tumor cell colonization in bone

Lysyl oxidase is a strong determinant of tumor cell colonization in bone. Short Title: LOX triggers tumor cell colonization in bone

... Introduction The lysyl oxidase (LOX) family of secreted copper-dependent amine oxidases consists of five paralogs: LOX and LOX-like 1-4 (LOXL 1-4). The primary function of the LOX family is to catalyse the ...

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Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

... ranking among the highest induced genes in the transcription arrays of BCC MSC , our attention focused on lysyl oxidase (LOX). LOX is a copper-dependent amine oxidase that catalyzes the ...

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Transcriptome Analysis of PPARγ Target Genes Reveals the Involvement of Lysyl Oxidase in Human Placental Cytotrophoblast Invasion

Transcriptome Analysis of PPARγ Target Genes Reveals the Involvement of Lysyl Oxidase in Human Placental Cytotrophoblast Invasion

... Human placental development is characterized by invasion of extravillous cytotrophoblasts (EVCTs) into the uterine wall during the first trimester of pregnancy. Peroxisome proliferator-activated receptor c (PPARc) plays ...

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Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

... siRNA scramble, LOXL4 staining was stronger for cells treated with atRA and strongly reduced for cells trans- fected with siRNA against LOXL4 (Fig. 4e). Negative control of gene extinction by siRNA against LOXL4 was ...

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en fr Role of endothelial and tumor lysyl oxidase like-2 to angiogenesis in clear cell renal cell carcinoma Rôle de la lysyl oxidase-like-2 endothéliale et tumorale au cours de l’angiogenèse dans le carcinome du rein à cellules claires

... that TG2 limited VEGF 165 -induced angiogenesis by impeding the binding of VEGF 165 to HSPGs, thus attenuating VEGF 165 signaling through VEGFR2 and endothelial cell migration.. Therefor[r] ...

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Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

... NADPH oxidase defects in patients with chronic granuloma- tous disease ( Segal et ...NADPH oxidase ( Rey et ...NADPH oxidase protein interaction potentially allows temporary and dose-dependent re- ...

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Bilirubin oxidase based enzymatic air-breathing cathode: Operation under pristine and contaminated conditions

Bilirubin oxidase based enzymatic air-breathing cathode: Operation under pristine and contaminated conditions

... carried out and as we already discusses, no negative effect was occur- ring due to the presence of bacteria and solid particles. 4. Conclusion Continuous operation of bilirubin oxidase cathode was investigated by ...

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Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

... NADPH oxidase defects in patients with chronic granuloma- tous disease (Segal et ...NADPH oxidase (Rey et ...NADPH oxidase protein interaction potentially allows temporary and dose-dependent re- ...

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Bacterial respiratory chain diversity reveals a cytochrome c oxidase reducing O2 at low overpotentials

Bacterial respiratory chain diversity reveals a cytochrome c oxidase reducing O2 at low overpotentials

... Acidithiobacillus ferrooxidans is an acidophilic bac- terium living in pH environment as low as pH 2. One of its metabolic chains couples ferrous iron oxidation to O2 reduction by an aa3 CcO (Supporting Infor- mation ...

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Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase.

Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase.

... Relative mitochondrial and cytoplasmic ligand concentrations were determined in WT by loading soluble extracts of purified mitochondria or cytosol onto RP-HPLC.. fractions containing the[r] ...

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Dynamics of the localization of the plastid terminal oxidase PTOX inside the chloroplast

Dynamics of the localization of the plastid terminal oxidase PTOX inside the chloroplast

... Dynamics of the localization of the plastid terminal oxidase PTOX inside the chloroplast... 2 Abstract.[r] ...

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NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

... xanthine/xanthine oxidase (Figure ...thine oxidase, SOD, which dismutates superoxide into hydrogen peroxide, and trolox, which is a potent radical scavenger, celastrol did not show a concentration-dependent ...

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Unique protonation states of aspartate and topaquinone in the active site of copper amine oxidase

Unique protonation states of aspartate and topaquinone in the active site of copper amine oxidase

... formed, a deprotonation is required for one of the amino acid residues followed by the protonation to the TPQ enol form is required since the amino acid residues near the act[r] ...

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Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1.

Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1.

... Deletion of COX14 or COA1 in coa2∆ cells restored WT levels of newly synthesized 3.. Cox1, whereas overexpression of Mss51 only partially returned Cox1 (Fig.[r] ...

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Putative role of cytokinin in differential ethylene response of twolines of antisense ACC oxidase cantaloupe melons

Putative role of cytokinin in differential ethylene response of twolines of antisense ACC oxidase cantaloupe melons

... Golding, J.B., Shearer, D., Wyllie, S.G., McGlasson, W.B., 1998. Application of 1-MCP and propylene to identify ethylene-dependent ripening processes in mature banana fruit. Postharvest Biology and Technology 14, 87–98. ...

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INVESTIGATION OF ANTIHEMOLYTIC, XANTHINE OXIDASE INHIBITION, ANTIOXIDANT AND  ANTIMICROBIAL PROPERTIES OF SALVIA VERBENACA L. AERIAL PART EXTRACTS.

INVESTIGATION OF ANTIHEMOLYTIC, XANTHINE OXIDASE INHIBITION, ANTIOXIDANT AND ANTIMICROBIAL PROPERTIES OF SALVIA VERBENACA L. AERIAL PART EXTRACTS.

... Key words: Salvia verbenaca L., Erythrocyte Oxidative Hemolysis, Xanthine Oxidase Inhibition, Antioxidant Activity, Antibacterial.. Activity and Antifungal Activity.[r] ...

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Monoamine oxidase activity in placenta in relation to manganese, cadmium, lead, and mercury at delivery.

Monoamine oxidase activity in placenta in relation to manganese, cadmium, lead, and mercury at delivery.

... Nadia Abdelouahab, Guy Huel, Alexander Suvorov, Bernard Foliguet, Valérie Goua, Ginette Debotte, Josiane Sahuquillo, Marie-Aline Charles, Larissa. Takser[r] ...

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Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase

Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase

... cereuis- iae is subject to a negative control by oxygen and heme’ and this regulation operates at the pretranslational level: the enzyme activity, together with the stead[r] ...

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The function of PROTOPORPHYRINOGEN IX OXIDASE in chlorophyll biosynthesis requires oxidised plastoquinone in Chlamydomonas reinhardtii

The function of PROTOPORPHYRINOGEN IX OXIDASE in chlorophyll biosynthesis requires oxidised plastoquinone in Chlamydomonas reinhardtii

... T he tetrapyrrole biosynthesis (TBS) pathway leads to bio- synthesis of chlorophyll, heme, and siroheme, which are indispensable components of cell metabolism, including energetic processes, such as ...

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