Lung injury
RAGE inhibition reduces acute lung injury in mice
... experimental lung injury, but its modalities and effects remain ...control. Lung injury was assessed by the analysis of blood gases, alveolar permeability, histology, AFC, and ...cytokines. ...
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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice.
... the lung follow- ing ozone exposure have been shown varying with ozone concentration, exposure duration, and animal species ...increased lung peroxynitrite production was associated with AMPK ...
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Secretory phospholipase A2 pathway in various types of lung injury in neonates and infants: a multicentre translational study
... Originality of the project This is the first study aimed at investigating the whole sPLA2 pathway in the above-described types of lung injury. To date, no study has addressed the functioning of the whole ...
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View of Patient Self-Inflicted Lung Injury: What the Intensivist Needs to Know
... induced lung injury · Patient self- inflicted lung injury · Effort respiratoire · Ventilation mécanique Abstract Nowadays, clinicians are familiar with the concept of VILI (ventilator induced ...
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Adenovirus-mediated fibroblast growth factor 1 expression in the lung induces epithelial cell proliferation: consequences to hyperoxic lung injury in rats.
... hyperoxic lung injury (Panos et ...lium injury and justify our choice of the rat hyperoxia model for investigating potential effects of FGF-1 on ...that lung epithelial proliferation was far ...
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Anti-Inflammatory effect of anti-TNF-α SiRNA cationic phosphorus dendrimer nanocomplexes administered intranasally in a murine acute lung injury model
... inflammation-associated lung injury as described 36 ...develops lung injury, the best known strategy is supportive care 37 ...of lung injury 37,38 ...
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Effects of inspiratory pause on CO2 elimination and arterial PCO2 in acute lung injury.
... Abstract A high respiratory rate associated with the use of small tidal volumes, recommended for acute lung injury (ALI), shortens time for gas diffusion in the alveoli. This may decrease CO 2 elimination. ...
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Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model.
... caspofungin in mouse lungs was previously assessed at Day 2 and no positive fungal cultures were collected in both the CaCasp0- and the CaCasp1-groups (data not shown). Furthermore, the lack of impact of caspofungin on ...
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Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury.
... mediated lung injury, and indicate that deficiency in IGF- 1R is associated with a higher capacity to endure and to recover from oxidant-induced ...acute lung injury. Hyperoxic exposure is ...
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Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/ acute respiratory distress syndrome patients: a pilot study
... acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) may develop sec- ondary abdominal pathologies associated with increased intra-abdominal pressure (IAP) and, vice versa, primary ...
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Gene Expression Profiles Characterize Inflammation Stages in the Acute Lung Injury in Mice
... Acute lung injury (ALI) is a diffuse lung injury which is characterized by a widespread capillary leakage leading to hypoxemia and low lung ...pancreatitis) injury of the ...the ...
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Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury
... Intratracheal infection and lung injury model. BAL was obtained at 24 hours by inserting a 20-gauge cath- eter into the trachea through which 1 ml of cold PBS was flushed back and forth 3 times. Total ...
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en fr Functional imaging of pulmonary ventilation and inflammation in an experimental model of lung injury Imagerie fonctionnelle de la ventilation et de l’inflammation pulmonaires lors d'agression pulmonaire aiguë expérimentale
... of lung injury is incredibly complex, and further complexified by the wide spectrum of clinical conditions leading to this syndrome ...Second, lung lesions are evolving over time, in several often ...
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View of Experimental Models for Acute Lung Injury
... geurs ont un intérêt tout particulier, car leurs poids intermé- diaires permettent la mise en place d ’une ventilation artificielle invasive plus aisément que chez la souris pour des raisons techniques évidentes. Ils ont ...
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View of The pathogenesis of transfusion-related acute lung injury
... acute lung injury) est défini cliniquement comme un œdème pulmonaire lésionnel survenant dans les six heures suivant la transfusion d ’un produit ...
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Poly(ADP-ribose) polymerase inhibition in acute lung injury. A reemerging concept
... nitrosative injury pathways that are triggered by oxygen- and nitrogen-centered oxidants and free radicals, which act in parallel or in synergy with PARP-mediated pathways of cell ...acute lung ...
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A Cellular Pathway Involved in Clara Cell to Alveolar Type II Cell Differentiation after Severe Lung Injury
... the lung is at the pseudoglandular stage and is filled with developing ...embryonic lung, clusterin is re-expressed in the lung tissue including in SBECs following influenza ...embryonic lung ...
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Circadian Rhythm Disruption Promotes Lung Tumorigenesis
... accelerates lung tumorigenesis To investigate the role of circadian rhythm disruption in tumorigenesis, we used pre-clinical GEMMs of human lung adenoma and ...after lung tumor initiation (jet lag ...
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Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma: E2F1 expression in human lung tumours
... human lung tumours E2F1 protein expression was studied on a panel of 58 lung tumour tissue samples by western-blotting using two monoclonal antibodies (Table 1, Figure ...normal lung tissues studied ...
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View of Lung transplantation: before, during and after… — Beneficial effects of lung transplantation and rehabilitation
... Effets de la transplantation sur la fonction respiratoire Avant la transplantation, la CVF et le VEMS sont largement inférieurs aux valeurs normales chez les candidats à la greffe (respe[r] ...
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