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Lung cancer cells

Pemetrexed Hinders Translation Inhibition upon Low Glucose in Non-Small Cell Lung Cancer Cells

Pemetrexed Hinders Translation Inhibition upon Low Glucose in Non-Small Cell Lung Cancer Cells

... NSCLC cells are subjected to chemotherapeutic ...in lung cancer cells, cisplatin treatment induces a protective response mediated by ERS [ 20 ...

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Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

... bated with 0.05–0.1 μ M Pt-ctpy. Cells were replated once a week. The number of population doublings (PD) was calculated as follows: PD = log 2 (N f /N o ), where N f is the final cell number and N o is the ...

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Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.

Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.

... interaction (Fig. 5a, middle panel). These results suggested that TSA sensitizes the cells to gefitinib's effect by enhancing Ku70 acetylation, leading to the subsequent release of BAX. To consolidate this result, ...

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Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells.

Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells.

... In normal epithelia, ZO-2 is expressed as two isoforms ZO-2A and ZO-2C. ZO-2C protein is 23 amino acids shorter at the N-terminus than ZO-2A [ 6 , 7 ]. Three others forms have also been described, two derived from form A ...

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Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib.

Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib.

... H1650 cells were much more sensitive to simultaneous inhibition by RNAi of both EGFR and c-MET pathways, but less effect was observed when pharmacological inhibitors were ...H1975 cells, the power of RNAi ...

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Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

... tumor cells, and this combined treatment represents a novel anticancer ...cell lung cancer (A549 and H1299) cells in vitro and in ...SF763 cells was shown by delayed tumor growth and ...

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Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells.

Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells.

... NSCLC cells To further assess the efficacy of the Y-27632/afatinib combina- tion, we evaluated their effect in abrogating the invasive phenotype in H1975 ...H1975 cells infiltrating into the collagen after a ...

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Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo

Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo

... nonsmall lung cancer cells ...carcinoma cells to affect the process of apoptosis, oxidative stress, lipid, and ion transportation and finally inhibit the growth of tumour ...

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AIF-regulated oxidative phosphorylation supports lung cancer development

AIF-regulated oxidative phosphorylation supports lung cancer development

... A549 cells that also compromised the expression of respiratory chain components (but not that of AIF) and resulted in reduced proliferation and diminished clonogenic potential of these human lung ...

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Distinct prognostic value of circulating anti-telomerase CD4+ Th1 immunity and exhausted PD-1+/TIM-3+ T cells in lung cancer

Distinct prognostic value of circulating anti-telomerase CD4+ Th1 immunity and exhausted PD-1+/TIM-3+ T cells in lung cancer

... c Fig. 2 Relationship between TERT-specific CD4 + Th1 response and blood immune factors in patients with NSCLC. a Heatmap illustrating hierarchical clustering (Euclidean distance) of 22 blood immune parameters (in rows) ...

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en fr Cancer stem cells in colon cancer Cellules souches cancéreuses et cancer du côlon

... murins précliniques, que l’inhibition de CD133, CD44 ou ALDH1 par différentes approches l’expression diminuaient la tumorigénicité des CSC dans le cancer du côlon (11–13). Aucune de ces stratégies n’a ...

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ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

... normal lung tissue specimens obtained from stage IA-IIB NSCLC patients, and of 27 lung tissue specimens obtained from COPD patients, were cryopreserved in RNAlater for 1 to 7 years before ...

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Exposure to Stressful Life Events and Lung Cancer Risk

Exposure to Stressful Life Events and Lung Cancer Risk

... Norwegian Cancer Registry is practically complete due to mandatory reporting of cancer diagnosis, thus selection bias as it pertains to cases is likely ...visible lung lesion. In total, 44 malignant ...

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en fr Lung cancer risk factors among women Facteurs de risque de cancer du poumon chez la femme

... of lung cancer (18) and has been suggested to be a potential confounder in the comparison of the lung cancer risk related to smoking consumption between genders ...with lung ...

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Screening for malnutrition in lung cancer patients undergoing therapy

Screening for malnutrition in lung cancer patients undergoing therapy

... were asked whether they had lost weight unintentionally over the last month and the last 6 months. The third module “diseases and their relation to nutritional needs” looks for a set of conditions that could potentially ...

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Surrogate markers predicting overall survival for lung cancer: ELCWP recommendations

Surrogate markers predicting overall survival for lung cancer: ELCWP recommendations

... Ovid Medline was searched using the OvidSP interface. Unless otherwise stated, search terms were MeSH terms (medical subject headings). MeSH terms were also combined with relevant free-text terms that were searched for ...

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Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

... T cells in the lung, recombinant mouse IL-1 β (R&D Systems, 100 ng/mouse) plus IL-23 (R&D Systems, 100 ng/mouse), or LPS (Lipopolysaccharide from ...

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Targeted photoredox catalysis in cancer cells

Targeted photoredox catalysis in cancer cells

... A549 cancer cells. Cells were treated with complex 1 (3 M) or cisplatin (200 M) or oxaliplatin (200 M) at 310 K for 2 h, washed and irradiated with 450 nm light (10 J/cm 2 ) followed by recovery ...

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Concise review: adult multipotent stromal cells and cancer: risk or benefit?: Adult stromal cells and cancer

Concise review: adult multipotent stromal cells and cancer: risk or benefit?: Adult stromal cells and cancer

... the lung metastases sites of mice bearing melanoma metastases 49 50 , ...of cells home to the lung when injected ...tumor cells, such as lung, kidney, liver or ...

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Challenges in lung cancer therapy during the COVID-19 pandemic

Challenges in lung cancer therapy during the COVID-19 pandemic

... Comment 2 www.thelancet.com/respiratory Published online April 9, 2020 https://doi.org/10.1016/S2213-2600(20)30170-3 pain, dyspnoea, and fever. Additionally, CT assessment of immune checkpoint inhibitor-related ...

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