Low doses
Can the effect of low doses of alcohol on subjective and physiological alertness of young drivers be balanced by effort?
... Effort only promotes alertness in the driving session without alcohol and it can be assumed that low doses of alcohol (0.2 and 0.5 g/l) do not allow to regulate the effort necessary to safety driving. Note ...
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Low Doses of Bisphenol A Induce Gene Expression Related to Lipid Synthesis and Trigger Triglyceride Accumulation in Adult Mouse Liver
... different doses of BPA (0, 5, 50, 500, and 5,000 lg/kg/day) through food ...of low doses of BPA on the hepatic transcriptome, more particularly on genes involved in lipid ...lower doses than ...
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Homologous Recombination is Involved in the Repair Response of Mammalian Cells to Low Doses of Tritium
... that low doses of [ 3 H]thymidine induce HR, and since HR protects against genome instability, we speculate that HR may participate in the adaptive ...of low radiation doses from tritiated ...
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Exposure of Adult Female Mice to Low Doses of di(2-ethylhexyl) Phthalate Alone or in an Environmental Phthalate Mixture: Evaluation of Reproductive Behavior and Underlying Neural Mechanisms
... Exposure of Adult Female Mice to Low Doses of di(2-ethylhexyl) Phthalate Alone or in an Environmental Phthalate Mixture: Evaluation of Reproductive Behavior and Underlying Neural Mechani[r] ...
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Perinatal BPA exposure at low doses impairs oral tolerance and immunization to ovalbumin in offspring rats at adulthood
... at low doses impairs oral tolerance and immunization to ovalbumin in offspring rats at adulthood Sandrine Ménard, Viorica Braniste, Mathilde Lévêque, Corinne Lencina, Manon Naturel, Lara Moussa, Soraya ...
2
Effects of low doses of bisphenol A on the metabolome of perinatally exposed CD-1 mice
... provides a powerful tool to detect metabolic changes induced by very low doses of EDs, allowing discrimination between several experi mental groups on the basis of over- or under expression of endogenous ...
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Low Doses of Gamma-Irradiation Induce an Early Bystander Effect in Zebrafish Cells Which Is Sufficient to Radioprotect Cells
... the low dose-rate ...the low protein secretion of irradiated cells, which implies that in ZF4 cells the ‘‘early bystander effect’’ described can be due to another soluble factor rather than a secreted ...
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Homologous Recombination is Involved in the Repair Response of Mammalian Cells to Low Doses of Tritium mologous Recombination is Involved in the Repair Response of Mammalian Cells to Low Doses of Tritium
... (low doses); genetic effects were neg- atively correlated with the energy emitted but were positively correlated with the energy deposited in the nucleus, suggesting that low-energy -particle ...
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Variation of performance, of self-reported alertness and effort as a function of low doses of alcohol and of driving experience
... 2.4 Procedure We used the same driving scenario for the three BAC sessions. It consisted of a two-lane mostly straight rural highway, with a few curves, no traffic density in a rela- tively flat environment. Before each ...
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Effects of low doses of esmolol on cardiac and vascular function in experimental septic shock
... that low doses of esmolol at 5 and 1 ...high doses of esmolol have consist- ently been associated with non-deleterious effects on cardiac and vascular functions in small-animal models of sepsis, the ...
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Dynamic metabolic disruption in rats perinatally exposed to low doses of bisphenol-A
... multiple doses (5) and time points (5) in rats up to PND200, to address the lasting metabolic consequences of perinatal exposure to low doses of BPA, and examined those effects despite physiological ...
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An untargeted metabolomics approach to explore the metabolic modulation of HepG2 cells exposed to low doses of bisphenol A and 17β-estradiol 2
... The model xeno-estrogen bisphenol A (BPA) has been extensively studied over the past two decades, contributing to major advances in the field of endocrine disrupting chemicals research. Besides its well documented ...
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Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay
... Previous in vitro investigations have mainly been conducted on human mammary epithelial cells or on human breast cancer cells, reflecting the impact of environmental factors on the earlier and later stages of ...
21
Pharmacometabolomics of docetaxel-treated human MCF7 breast cancer cells provides evidence of varying cellular responses at high and low doses
... at low concentration [ 13 , 46 ]. In this study, at low dose of DTX, we found blockade of CBS as well as ...to low dose of DTX [ 12 , 15 ...at low dose of DTX may reflect NO production and at ...
15
Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model
... potential low and high weight gain individuals in the LFD and HFD groups were equally distributed into the sub-groups destined for treatment or not with TCDD in order to avoid a biased TCDD effect (see Table S1 ...
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Perinatal oral exposure to low doses of bisphenol A, S or F impairs immune functions at intestinal and systemic levels in female offspring mice
... both doses 5 and 50 μg/kg BW/d, highlighting the fact that the effect of this bisphenol on intestinal im- mune response involves a different mechanism com- pared to ...the low dose of BPS provoked an in- ...
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Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.
... Hepatic mRNA expression of 8 circadian genes in male lean and obese mice treated or not 529. with the cocktail containing the 11 drugs at concentrations ranging from 10 to 10 6 ng/l[r] ...
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Effets de doses croissantes de NaCl sur le comportement du bananier et la morpho diversité de champignons du sol
... A BSTRACT : Banana is exposed to many problems including excessive soil salinity and irrigation waters that decrease productivity. This trial was conducted to evaluate the effects of salinity on the behavior of banana ...
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Fumonisins at doses below EU regulatory limits induce histological alterations in piglets
... to low doses of FBs, including a dose below the EU regulatory ...a low dose ...at doses below the EU regulatory limit cause histological lesions in several ...regulatory doses should be ...
15
Chimiothérapie à hautes doses comme stratégie pour contourner la résistance aux médicaments dans les tumeurs solides
... En dehors des tumeurs germinales, diverses autres indications ont été testées. Dans le cancer du sein, la plupart des études utilisant les thérapies de hautes-doses ont montré une amélioration de la survie sans ...
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