Lipid-lowering
The Future of Lipid-Lowering Therapy
... is lowering plasma low-density lipoprotein (LDL) cholesterol levels with primarily statins, which are demonstrated to reduce major vascular events by 23% for every ...using lipid-lowering drugs reach ...
17
Prevention of cardiovascular disease: plea for a rationale use of diet and lipid-lowering drugs.
... a lipid-lowering drug according to the Belgian ...received lipid-lowering drugs (because total cholesterol level remained higher than 250 mg/dl or triglycerides remained higher than 200 mg/dl ...
3
Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II study.: Predictors of declines in LDL-cholesterol
... to lipid lowering drug treatment and favourable changes in diet and physical activity, we estimated the reduction in LDL-cholesterol that would be observed if 1) all participants in need of ...
45
Primary prevention with lipid lowering drugs and long term risk of vascular events in older people: population based cohort study
... of lipid lowering drugs, whereas no decrease was observed for risk of coro- nary heart ...of lipid lowering drugs were at higher vascular risk than non-users, and an indication bias would have ...
9
Lipid lowering agents, cognitive decline, and dementia: the three-city study.
... Abstract The aim of this prospective cohort study was to evaluate the effects of lipid lowering agent (LLA) intake on cognitive function in 6830 community-dwelling elderly persons. Cognitive performance ...
10
Lipid-lowering drugs associated with slower motor decline in the elderly adults.
... (7). Lipid metabolism abnormalities may also play a role: lower HDL-cholesterol has been associated with slower WS in the elderly (8), with cholesterol known to modify the association between chronic inflammation ...
25
LIPID LEVELS AND CARDIOVASCULAR RISK IN ELDERLY WOMEN: A GENERAL POPULATION STUDY OF THE EFFECTS OF HORMONAL TREATMENT AND LIPID-LOWERING AGENTS
... LIPID LEVELS AS A FUNCTION OF LLA, OR/AND HT Table 3 shows that women not treated by either LLA or HT (group 1) had significantly higher adjusted means of TC (by ...The lipid profile in women taking only ...
23
Effects of glucose-lowering agents on vascular outcomes in type 2 diabetes: A critical reappraisal.
... with lipid- lowering compounds (statins), antiplatelet agents (aspirin), blockers of the renin-angiotensin system (angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists) or various ...
29
The complexity of lipoprotein (a) lowering by PCSK9 monoclonal antibodies
... Interestingly, significant reductions in Lp(a) were not seen in the single phase I trial of ALN-PCS, a RNAi that reduces en- dogenous PCSK9 production, despite a 40% reduction in LDL- C [27,28]. Reductions in Lp(a) ...
9
Pharmacogenomics of blood lipid regulation
... of Lipid Lowering Drugs and Diet Network (GOLDN) and Action to Control Cardiovascular Risk in Diabetes (ACCORD) studies identified the gene PBX4 encoding the pre-B-cell leukemia homeobox 4 gene as a ...
24
Biogenesis and fate of lipid droplets
... Man-made dietary emulsions are often prepared using an oil phase and vegetable lecithins as emulsifiers. Robert et al. review here the impact of vegetable lecithins on lipoprotein metabolism, hepatic lipogenesis, blood ...
5
Lipid Droplets in Unicellular Photosynthetic Stramenopiles
... as mentioned above, seipin interacts with different proteins depending on the organism. In yeast, the seipin homolog Fld1 function depends on its interaction with Ldb16 ( Wang C.-W. et al., 2014 ). Yet this seems to be ...
22
Nanoparticle-lipid interaction: job scattering plots to differentiate vesicle aggregation from supported lipid bilayer formation
... 4. Conclusions In this work we studied the interaction of engineered nanoparticles with lipid vesicles, and searched for prominent features pertaining to their scattering properties. The first goal was to provide ...
12
The lipid biochemistry of eukaryotic algae
... Hitchcock, Plant lipid biochemistry: the biochemistry of fatty acids and acyl lipids with particular 2232. reference to higher plants and algae [by] C[r] ...
97
Detergent assisted lipid extraction for biodiesel.
... References Martínez EJ, Raghavan V, González-Andrés F & Gómez X (2015) New Biofuel Alternatives: Integrating Waste Management and Single Cell Oil Production. International journal of molecular sciences ...
1
Lowering the potential of electroenzymatic glucose oxidation on redox hydrogel-modified porous carbon electrode
... In conclusion, a glucose oxidation current density of 50 mA cm 2 was recorded at 0.3 V using MgO-templated porous carbon, with 38 nm average diameter pores, modi fied with a GOx hydrogel[r] ...
6
Supported lipid bilayers on biocompatible polysaccharide multilayers
... have lipid mobilities that are comparable to those on various PEG polymer cushions and only slightly lower than those on ...in lipid mobility between the two ...high lipid mobility in neutral ...
27
Lipid mediators as regulators of lipid and energy metabolism during energy balance derangement in animal models
... It has been suggested that regulation of body composition through food Intake and body metabolism is influenced by a balance between the endocannabinoid (EC) and the PPAR-α systems (Naughton et al., 2013). The ...
144
Proteomic Analysis of Lipid Droplets from Caco-2/TC7 Enterocytes Identifies Novel Modulators of Lipid Secretion
... during lipid absorption have clearly shown that a dynamic accumulation and depletion of TAG in LD occurs during the process of fat absorption, suggesting that TAG present in cytosolic LD contribute to chylomicron ...
18
Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane
... are known to mediate apical efflux but not absorption of sterols, were also detected in D1, D2 and, to a lesser ex- tent, in D3. Finally, ABCA1 remained below the detection limit in the total homogenate (I), was barely ...
16