Leukemic cells
E4F1 dysfunction results in autophagic cell death in myeloid leukemic cells.
... Abstract Summary The multifunctional E4F1 protein was originally identified as a cellular target of the E1A adenoviral oncoprotein. Although E4F1 is implicated in several key oncogenic pathways, its roles in ...
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Ring nanoelectrodes integrated into microwell arrays for the analysis of mitochondria isolated from leukemic cells
... Ring nanoelectrodes integrated into microwell arrays for the analysis of mitochondria isolated from leukemic cells Gabriel Lemercier, Fadhila Sekli-Belaidi, Venkata Suresh Vajrala, Steph[r] ...
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SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity
... SHIP-1 cells were significantly resistant to CD95-induced cell death when compared with Jurkat ...Ev cells, pro-caspase-8, -3 and PARP cleavage is observed at any time point of 7C11 Ab treatment, while the ...
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Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production
... a leukemic cell model for investigat- ing the antioxidant response in cells performing ...tumor cells ( Obre and Rossignol, 2015 ), although expression or muta- tion of proteins regulating ...
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HBZ impedes the Menin function and up-regulates the transcription of the hTERT gene in leukemic cells
... Cite this article as: Borowiak et al.: HBZ impedes the Menin function and up-regulates the transcription of the hTERT gene in leukemic cells. Retrovirology 2011 8(Suppl 1):A182. Submit your next manuscript ...
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E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
... modulate increased ROS levels or cell death in E4F1 KO HS cells (Fig. S7). Our data rather point to a more direct role of E4F1 in the regulation of mitochondrial activities that impinge on ROS levels. Indeed, ...
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Dasatinib-Loaded Erythrocytes Trigger Apoptosis in Untreated Chronic Myelogenous Leukemic Cells
... target cells is necessary to bolster the toxicity of the erythrocyte dasatinib pool To assess the nature of dasatinib exchanges between dasatinib- loaded erythrocytes and naïve CML cells, the effect of ...
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A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines
... Ionizing irradiation- and cytotoxic drug-induced DSBs, including those caused by fludarabine, are repaired mainly by NHEJ which is the major cell cycle- independent repair pathway for this type of DNA damage in mammalian ...
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en fr Molecular bases of the interaction between B leukemic cells of chronic lymphocytic leukemia and nurse-like cells : news rational for news therapeutics targets in chronic lymphocytic leukemia Bases moléculaires de l'interaction entre cellules B de leucémie lymphoïde chronique et nurse like cells : nouveaux rationnels pour de nouveaux traitements dans la leucémie lymphoïde chronique
... Enfin, cette voie de signalisation fait actuellement l’objet d’une attention toute particulière car de nombreux inhibiteurs des protéines de signalisation sont en c[r] ...
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Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia
... 5. Conclusions In this study, we report that the newly identified tumor suppressor and cholesterol metabolite DDA potentiated and sensitized in vitro and in vivo leukemic cells lines and primary AML samples ...
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Telomere shortening correlates with leukemic stem cell burden at diagnosis of chronic myeloid leukemia.
... (PB) cells of patients with chronic myeloid leukemia (CML) has been shown to correlate with disease stage, prognostic scores, response to therapy, and disease ...stem cells (HSC) in the bone marrow of CML ...
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Ito Cells Are Liver-Resident Antigen-Presenting Cells for Activating T Cell Responses
... Ito cells in vivo, we conducted adoptive transfers of CFSE-labeled HA-specific CD8 + T cells to GFAP-HA transgenic or wild-type recipient ...T cells (CL4) to GFAP-HA recipient mice caused activation ...
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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells
... B13 cells were plated 3 days prior to transduction in 12-well ...The cells were harvested 4 days post-transduction in 350 μl lysis solution containing 10 μl/ml β-mercap- toethanol and 1 μl RNA isolation ...
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Functional Assessment of the Induced Pluripotent Stem Cells (iPSC)-derived β-like Cells
... Stem Cells (iPSC)-derived -like Cells Manon Jaffredo 1 , Nicole Krentz 2 , Benoite Champon 2,3 , Fernando Abaitua 2 , Antoine Pirog 4 , Nicola Beer 2 , Anne Clark 3 , Yannick Bornat 4 , Sylvie Renaud 4 , ...
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Innate lymphoid cells
... phoid cells, ILC) sont des effecteurs tissulaires qui se distinguent des lymphocytes B et T par l’absence de récepteur de l’antigène issu de réarrangements ...
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Dynamic Modelling and Optimisation of Microbial Fuel Cells and Microbial Electrolysis Cells
... Although this work presented a simplified fast convergence model, it has many limitations. For example, it does not consider multi-population microbial consortium in the MFC, it considers first order reactions between ...
180
Inside cardiac stem cells
... Parmi eux, le gène Brachyury, un marqueur du mésoderme précoce, demeure présent jusqu’au stade du progéniteur multipotent mais disparaît lorsque la différenciation cardiov[r] ...
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Factorizations in Schubert Cells
... In order to prove (3.2) when the ring R is not commutative, it will be useful to label the crossing points of the pseudo-line arrangement Γ of the reduced decomposition i = (i 1 ,.. Proo[r] ...
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Chondrogenic Differentiation of Adult Mesenchymal Stem Cells and Embryonic Stem Cells
... This study compares the potential of pluripotent embryonic carcinoma cells (ECCs) and MSCs for cartilage histogenesis in collagen scaffolds in vitro, and investigates the asso[r] ...
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Embryonic stem cells or induced pluripotent stem cells? A DNA integrity perspective.: DNA integrity of iPS cells
... only cells with pristine genetic information should be considered for use is certainly a ...normal cells precludes a strict definition of pristine genetic information, but also because of the cell/tissue ...
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