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Ischemia-reperfusion

Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion

Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion

... ischemia-reperfusion Stephen Hurst 1 , Fabrice Gonnot 2 , Maya Dia 2 , Claire Crola Da Silva 2 , Ludovic Gomez 2 and Shey-Shing Sheu 1 Abstract The mitochondrial permeability transition pore (mPTP) plays a ...

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Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and may modulate renal lipid metabolism in rats.

Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and may modulate renal lipid metabolism in rats.

... renal ischemia/reperfusion (I/R) damage in rodent ...renal ischemia lasted 45 min. After 48-hour reperfusion, we observed significantly improved renal function parameters, reduced apoptotic ...

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Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury

Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury

... or ischemia-reperfusion ...in ischemia/reperfusion injury (IRI) of the liver graft, which has been considered as one of major problems influencing outcome after liver ...

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Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.

Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.

... Abstract Ischemia/reperfusion injury occurring during liver transplantation is mainly due to the generation of reactive oxygen species (ROS) upon ...liver ischemia reperfusion injury when ...

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Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

... oxygen and nitrogen species (RONS) that damage DNA, among other cellular molecules. Base excision repair (BER) is initiated by DNA glycosylases and is crucial in repairing RONS-induced DNA damage; the alkyladenine DNA ...

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Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair.

Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair.

... kidney ischemia-reperfusion model, that extensive renal tissue injury such as proximal tubule necrosis and outer medulla congestion occurred during the reperfusion phase following 60 min of ...

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Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

... 4.1. Clinical implication In this study, we examined the effects of a dietary fatty acid profile with high plant and marine n-3 PUFA, low saturated fatty acids and n-6 PUFA, and without trans- fatty acids. This indicates ...

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Activation of the calcium-sensing receptor before renal ischemia/reperfusion exacerbates kidney injury

Activation of the calcium-sensing receptor before renal ischemia/reperfusion exacerbates kidney injury

... by ischemia/reperfusion (I/R) favours apoptosis in car- diomyocytes, hepatocytes and ...30-min ischemia and 48-hour reperfusion, and in a 6-year cohort of kidney transplant recipients ...

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Infrared optical imaging of matrix metalloproteinases (MMPs) up regulation following ischemia reperfusion is ameliorated by hypothermia

Infrared optical imaging of matrix metalloproteinases (MMPs) up regulation following ischemia reperfusion is ameliorated by hypothermia

... the proof of concept that NIR fluorescent imaging can be used in situ to assess the mechanisms involved in cerebral ischemia. The expression of MMP-9 corresponded well with the spatial and temporal activation of ...

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Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and modulates renal lipid metabolism in rats

Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and modulates renal lipid metabolism in rats

... Sacks 1 , Wuding Zhou 1 1 King’s College London, United Kingdom; 2 Xi’an Jiaotong University, China Collectin-11 (CL-11) is a newly identified collectins of the innate immune system and recently has been suggested to ...

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Direct intraperitoneal resuscitation with lidocaine, methylene blue and pentoxiphylline combination does not decreases inflammation after intestinal ischemia-reperfusion injury in rats.

Direct intraperitoneal resuscitation with lidocaine, methylene blue and pentoxiphylline combination does not decreases inflammation after intestinal ischemia-reperfusion injury in rats.

... 20. Salehi P, Madsen K, Zhu J, Castillo E, Avilla J, Lakey JR, Churchill TA. Alleviating ischemia-reperfusion injury in small bowel. Am J of Transplant. 2004;4(5):728-737. PMID: 15084167. 21. Elhakim M, ...

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Cardiac remodeling and higher sensitivity to ischemia-reperfusion injury in female rats submitted to high-fat high-sucrose diet: an in vivo / ex vivo longitudinal follow-up

Cardiac remodeling and higher sensitivity to ischemia-reperfusion injury in female rats submitted to high-fat high-sucrose diet: an in vivo / ex vivo longitudinal follow-up

... ischemia and mostly reflow are well-known to induce high oxidative stress, which is exacerbated here by the 5-month high-fat high-sucrose ...an ischemia-reperfusion protocol and has been shown to be ...

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Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non‑obese type 2 diabetic Goto‑Kakizaki rats

Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non‑obese type 2 diabetic Goto‑Kakizaki rats

... myocardial ischemia reperfusion (I/R) injury, is a major cause of morbidity and mortality in type 2 diabetic ...myocardial ischemia/reperfusion ...simulated ischemia/reperfusion ...

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Renal ischemia/reperfusion decreases the expression of DPP-4

Renal ischemia/reperfusion decreases the expression of DPP-4

... Renal ischemia/reperfusion decreases the expression of DPP-4 Type 4 dipeptidyl-peptidase 4 (DPP-4) is a serine protease expressed at the surface of most epithelia, including renal proximal tubules ...renal ...

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Protective signaling of oxytocin in an in vitro model of myocardial ischemia - reperfusion

Protective signaling of oxytocin in an in vitro model of myocardial ischemia - reperfusion

... during reperfusion involves Akt phosphorylation and translocation to the nucleus, where it causes an increase in protective ANP synthesis and ...of ischemia - reperfusion injury, ANP release from ...

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Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart

Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart

... to ischemia-reperfusion ...to ischemia-reperfusion injury in animals treated with ethanol [ 39 ...to ischemia-reperfusion injury in our ...

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en fr Protector effect of hydrogen sulfure, protein C activated and dexamethason in the hemodynamic and inflammatory modulation in ischemia-reperfusion Effet protecteur du sulfure d'hydrogène, de la protéine C activée et de la dexamétasone dans la modulation hémodynamique et inflammatoire de l'ischémie/reperfusion

... Le monoxyde d’azote est produit sous l’action des NO synthases (NOS) constitutives ou inductibles à partir de la L-arginine en présence d’oxygène et de cofacteurs (Murakami, Nakatani et al. 1997). Il s’agit d’une ...

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View of Renal damage following ischemia-reperfusion

View of Renal damage following ischemia-reperfusion

... Introduction L ’insuffisance rénale aiguë (IRA) définie par les critères de RIFLE [risk (class R), injury (class I) and failure (class F)] ou AKIN (Acute Kidney Injury Network) affecte plus d ’un tiers des patients de ...

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en fr New mechanisms of protection of cardiomyocytes from ischemia / reperfusion injury Nouveaux mécanismes de protection des cardiomyocytes contre les lésions d'ischémie / reperfusion

... This leads to a reversal of the mitochondrial F1Fo ATP synthase as a way to maintain a potential: the enzyme actively transfers protons from the matrix to the intermembrane space but at [r] ...

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Acute Induction of Translocon-Mediated Ca2+ Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

Acute Induction of Translocon-Mediated Ca2+ Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

... 49. Sleiman, N.H.; McFarland, T.P.; Jones, L.R.; Cala, S.E. Transitions of protein traffic from cardiac ER to junctional SR. J. Mol. Cell. Cardiol. 2015, 81, 34–45, doi:10.1016/j.yjmcc.2014.12.025. 50. Hajnóczky, G.;  ...

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