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Inflammatory cytokines

The Effects of Pro-inflammatory Cytokines on the L-type Calcium Current in Mouse Ventricular Myocytes

The Effects of Pro-inflammatory Cytokines on the L-type Calcium Current in Mouse Ventricular Myocytes

... Abstract Cytokines are immune system modulators that are secreted in response to an ...pro-inflammatory cytokines, locally or systemically, has many deleterious ...of cytokines. Three ...

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Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibiotics

Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibiotics

... an inflammatory context in absence of BA accumulation, remains ...an inflammatory stress could modulate deformation of BC and related disturbances induced by these cholestatic drugs using differentiated ...

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Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

... key inflammatory cytokines involved in fatty liver diseases [ 16 , 17 ...other cytokines, such as MCP-1, IL-6, IL-8, IL-18, RANTES and Il-10 are also associated to fatty liver [ 18 , 19 ...and ...

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Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

... ATM is a kinase that plays a key pivotal role in mediating DSB signal transduction for DDR initiation (Figure 3, Figure 4). ATM deficiency causes the ataxia telangiectasia (A-T) syndrome, which is associated with ...

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Regulation of Transdifferentiation and Retrodifferentiation by Inflammatory Cytokines in Hepatocellular Carcinoma

Regulation of Transdifferentiation and Retrodifferentiation by Inflammatory Cytokines in Hepatocellular Carcinoma

... pro-inflammatory cytokines (TNF-Į, IL-6, IL-1 β), immunosuppressive factors (TGF-β, IL-10 and CCL22), proangiogenic factors (VEGF, IL-8, CXCL10) and matrix metalloproteinases (MMP9) that trigger matrix ...

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On-line hemodiafiltration did not induce an overproduction of oxidative stress and inflammatory cytokines in intensive care unit-acute kidney injury

On-line hemodiafiltration did not induce an overproduction of oxidative stress and inflammatory cytokines in intensive care unit-acute kidney injury

... and inflammatory cytokines in intensive care unit-acute kidney injury Kada Klouche, Laurent Amigues, Marion Morena, Vincent Brunot, Anne Marie Dupuy, Audrey Jaussent, Marie Christine Picot, Noémie ...

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Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand.

Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand.

... most likely through negative regulation of endogenous IL- 1 responses as well as CD40L-induced IL-1 in DC. While the RPA technique did not reveal IL-1 transcripts in un- stimulated immature DC, it has been reported that ...

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The release of pro-inflammatory cytokines is mediated via mitogen-activated protein kinases rather than by the inflammasome signalling pathway in keratinocytes

The release of pro-inflammatory cytokines is mediated via mitogen-activated protein kinases rather than by the inflammasome signalling pathway in keratinocytes

... the inflammatory process in keratinocytes by MSU, we analyzed the gene expression profile of HaCaT cells incubated for 12 h with MSU at 1mg/ml (Figure ...of cytokines expression (IL-6 & CXL8/IL8) but ...

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Modulation of T cell antigen receptor signaling in CD8+ T lymphocytes following priming with homeostatic and inflammatory cytokines

Modulation of T cell antigen receptor signaling in CD8+ T lymphocytes following priming with homeostatic and inflammatory cytokines

... The percent of cytokine-primed and naïve 8.3-NOD CD8+ T cells which formed conjugates with the NRP-A7 peptide-loaded RMAS-Kd cells was divided by the percent ofthose cells which formed[r] ...

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Transcriptional interactions of transforming growth-factor-beta with pro-inflammatory cytokines.

Transcriptional interactions of transforming growth-factor-beta with pro-inflammatory cytokines.

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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In vivo immune signatures of healthy human pregnancy : inherently inflammatory or anti-inflammatory?

In vivo immune signatures of healthy human pregnancy : inherently inflammatory or anti-inflammatory?

... anti-inflammatory cytokines and inhibitors involved in human immune regulation, this analysis was extended in approximately every second woman (n = 120) to a panel of five additional pro-inflammatory ...

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Dendrimers as anti-inflammatory agents

Dendrimers as anti-inflammatory agents

... Uniterms: Dendrimers. Nanocarriers. Anti-inflammatory agents. Cyclooxygenase (COX-2). Inducible nitric oxide synthase (iNOS). Pro-inflammatory cytokines. Dendrímeros constituem uma classe intrigante ...

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Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4

Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4

... of inflammatory cytokines (IL-1β, TNF-α and IFN-γ), rather than a single cytokine, may be useful targets for therapeutic interventions against pancreatic β-cell ...

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The Interleukin-17 Family of Cytokines in Breast Cancer

The Interleukin-17 Family of Cytokines in Breast Cancer

... of cytokines has revealed critical roles in inflammatory disease and seems deeply implicated in cancer development [ 105 ...family cytokines in BC ...IL-17 cytokines also act indirectly on ...

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MODULATING CYTOKINES AS TREATMENT FOR AUTOIMMUNE DISEASES AND CANCER

MODULATING CYTOKINES AS TREATMENT FOR AUTOIMMUNE DISEASES AND CANCER

... of cytokines or other protein ligands that signal via a heterodimeric receptor ...of cytokines in human autoimmune and inflammatory diseases, many biologics targeting cytokines and their ...

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Etude d'une voie de signalisation intervenant dans la production de cytokines par les lymphocytes T

Etude d'une voie de signalisation intervenant dans la production de cytokines par les lymphocytes T

... Th2. Cependant, on ne peut pas exclure dans ces modèles le rôle d’autres paramètres comme l’état d’épuisement (exhaustion) de la CPA. Plusieurs études utilisant des APL (Ligands Peptidiques Altérés) ont plutôt montré ...

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Cytokines and growth factors cross-link heparan sulfate

Cytokines and growth factors cross-link heparan sulfate

... many cytokines and growth factors, which depends on the architecture of their HS binding ...of cytokines and growth factors may not simply be confined to the activation of cognate cellular ...

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Rôle des cytokines MIF dans l'interaction entre le puceron et sa plante hôte

Rôle des cytokines MIF dans l'interaction entre le puceron et sa plante hôte

... Les cytokines MIF étant connues chez les vertébrés comme des régulateurs majeurs des fonctions de défense, nous avons émis l'hypothèse de leur implication dans la manipulation des défenses de la plante ...

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Étude in vitro de l’implication des cytokines de type Th17 dans la fibrose hépatique

Étude in vitro de l’implication des cytokines de type Th17 dans la fibrose hépatique

... littérature indiquent que les cellules LX2 peuvent répondre aux cytokines de la famille de l’IL- 10 ainsi qu’à l’IL-17A et à l’IL-17F (Zhang et al., 2006). Par la suite, nous avons décidé d’évaluer l’action de ...

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