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in vivo mouse model

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model

... metastasis in nude mice [9,12,20,26], but enhance metastasis in immunosuppressed newborn rats ...use in adult mouse ...effect in cancer/metastasis. So far, the in vivo ...

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The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: In vivo mouse model

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: In vivo mouse model

... metastasis in nude mice [9,12,20,26], but enhance metastasis in immunosuppressed newborn rats ...use in adult mouse ...effect in cancer/metastasis. So far, the in vivo ...

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Masitinib combined with standard Gemcitabine chemotherapy : in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model

Masitinib combined with standard Gemcitabine chemotherapy : in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model

... resulted in resensitisation of resistant pancreatic cell lines in ...lines. In this study, masitinib was used at 5 and 10 m M over a 72-hour incubation ...used in the clinical setting, but ...

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A hemophilia A mouse model for the in vivo assessment of emicizumab function

A hemophilia A mouse model for the in vivo assessment of emicizumab function

... its in vivo functional analysis to primate models of acquired ...novel mouse model allowing to examine Emicizumab ...activity in a diluted aPTT and thrombin generation assays similar to ...

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Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer

Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer

... variable in breast tumors [ 23 ]. The PyMT Transgenic Mouse as a Model to Study Mammary Cancer With In Vivo Imaging Carcinogenesis in the PyMT mouse presents similarities ...

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Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI

Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI

... ex vivo or in vitro and using cell culture and drosophila model ...conducted in mouse models of tauopathy, and their results have been ...performed in transgenic mice expressing ...

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A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1 beta as relevant therapy for gout patients

A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1 beta as relevant therapy for gout patients

... deposition in the synovial fluid of patients, known for a long time ...ex vivo cultures of macrophages were instrumental in the identification of the NLRP3 ...inflammasome. In addition, ...

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Machine learning based white matter models with permeability: An experimental study in cuprizone treated in-vivo mouse model of axonal demyelination

Machine learning based white matter models with permeability: An experimental study in cuprizone treated in-vivo mouse model of axonal demyelination

... The model proposed by Nedjati et ...standard model-fitting approaches based on minimization of (non- linear) least-squares because it is more computationally efficient; it is less prone to local minimum ...

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Live intramacrophagic Staphylococcus aureus as a potential cause of antibiotic therapy failure observations in an in vivo mouse model of prosthetic vascular material infections

Live intramacrophagic Staphylococcus aureus as a potential cause of antibiotic therapy failure observations in an in vivo mouse model of prosthetic vascular material infections

... HAL Id: hal-01834453 https://hal-univ-rennes1.archives-ouvertes.fr/hal-01834453v2 Submitted on 6 Sep 2018 HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research ...

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Knockout mouse model generated by CRISPR technology to study the function of BSP proteins on male fertility in vivo

Knockout mouse model generated by CRISPR technology to study the function of BSP proteins on male fertility in vivo

... resulted in elimination of the entire sequence between exon 2 and exon 1 of the Bsph1 and Bsph2 genes (Fig ...transcripts in the disrupted ...RT-PCR in homozygous Bsph1/2 DKO mice ...completely ...

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The characterization of a mouse model of transient stroke using ex vivo MR microscopy and in vivo MR imaging

The characterization of a mouse model of transient stroke using ex vivo MR microscopy and in vivo MR imaging

... Specifically, the overall goals of this thesis are twofold: (1) to exploit the multiple relaxation mechanisms and varying tissue-dependent affinities of different MR contr[r] ...

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Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro

Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro

... studied in vivo and in vitro on adult mouse and isolated nerve-muscle preparations expressing the mature muscle α1 2 β1δε ...mice in vivo, using a minimally invasive ...

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Celecoxib reduces glucocorticoids in vitro and in a mouse model with adrenocortical hyperplasia

Celecoxib reduces glucocorticoids in vitro and in a mouse model with adrenocortical hyperplasia

... inhibitor. In bone, Prkar1a inhibition is associated with COX2 activation and prostaglandin E2 (PGE2) production that, in turn, activates proliferation of bone stromal ...effect in PPNAD. In ...

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Impact of DHA intake in a mouse model of synucleinopathy

Impact of DHA intake in a mouse model of synucleinopathy

... 2007). In sporadic forms of PD, αSyn accumulation and deposition into Lewy bodies is a neuropathological hallmark of the disease, essential for its definitive diagnosis (Dickson et ...which in turn may ...

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Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer’s disease

Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer’s disease

... In the present study, to determine if purely vascular or neuronal dysfunction were responsible for the decreased neurovascular coupling occurring during AD, we used either direct blood vessels stimulation, or ...

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Comparison of 3D Deformable Models For in vivo Measurements of Mouse Embryo from 3D Ultrasound Images

Comparison of 3D Deformable Models For in vivo Measurements of Mouse Embryo from 3D Ultrasound Images

... initialization and convergence problems with in vivo images. Manual interactions are usually required with the SMD model and made very efficient within a clever and intuitive user-friendly interface. ...

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Mouse model for bilateral adrenal hyperplasia

Mouse model for bilateral adrenal hyperplasia

... in vivo evidence that the absence of RI α subunit of PKA is sufficient to explain autonomous adrenal hyperactivity and bilateral hyperplasia observed in ...characters in adult ...

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Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches

Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches

... only in vitro approaches can be used to experimentally assess the toxicology risk in humans, we used an animal model to compare in vitro findings obtained with this organotypic culture system ...

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In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A

In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A

... measured in plasma of mice expressing VWF-WT & VWF-DEL, three and five days post-HGT, ...stable in siNEG-treated and untreated mice, whereas siDEL- treatment, resulted in a 25% increase in ...

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In Vivo Imaging Biomarkers in Mouse Models of Alzheimer's Disease: Are We Lost in Translation or Breaking Through?

In Vivo Imaging Biomarkers in Mouse Models of Alzheimer's Disease: Are We Lost in Translation or Breaking Through?

... 3.2.1. In Vivo Multiphoton Microscopy Imaging. In transgenic mice, in vivo multiphoton microscopy is a brain imaging modality that allows to image amyloid deposits and associ- ated ...

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