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In vitro cellular models

Predictive Toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data.

Predictive Toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data.

... manifested in the activa- tion of ROS, followed by a pro-inflammatory response and DNA damage leading to cellular apoptosis and mutagen- esis ...employed in our ...4). In-vitro studies ...

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Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models

Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models

... differences in the trends of metabolite concentra- ...resulted in the accumulation of high levels of malate compared to PEP (Figures 2D, 3D), both of which are precursors of ...results in the ...

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Development of conducting polymer devices for the monitoring of in vitro barrier tissue models

Development of conducting polymer devices for the monitoring of in vitro barrier tissue models

... TJs in their apical cellular membrane and are highly resistive when cultured in ...form cellular clusters with dimensions well below the circular-shaped trap diameter, ...cells in ...

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Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

... of in vitro cell biology studies are per- formed using cell monolayers cultured on flat substrates, there is growing evidence that 2D cell cultures fail to recapitulate the ar- chitecture of living tissues, ...

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In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal

In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal

... matrices in order to stimulate the different cell ...embedded in Matrigel and cultured with retinoic acid, and hepatocyte differentiation is achieved using a specific maturation ...cesses in NASH [ ...

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In Vitro Dermal Safety Assessment of Silver Nanowires after Acute Exposure: Tissue vs. Cell Models

In Vitro Dermal Safety Assessment of Silver Nanowires after Acute Exposure: Tissue vs. Cell Models

... be in direct contact with skin. There are very few studies on the cellular toxicity of AgNW and no studies that have specifically evaluated the potential toxicity from dermal ...two models, human ...

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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease

... toxicity in human iPSC- derived dopaminergic cultures and primary rat ...aggregation in microfluidic ...tinct cellular populations. As depicted in Fig. 2 a in our first experiment, we ...

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Cellular and molecular aspects of cell therapy in mouse models of Parkinson's disease and traumatic brain injury

Cellular and molecular aspects of cell therapy in mouse models of Parkinson's disease and traumatic brain injury

... 6 Netrin-1, suggérant un rôle pour la Netrin-1 dans la formation de la voie dopaminergique pendant le développement (Xu et al., 2010). Grâce au même type d’approche de neuroanatomie, nous avons également montré que ...

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Absence of p.R50X Pygm read-through in McArdle disease cellular models

Absence of p.R50X Pygm read-through in McArdle disease cellular models

... improvement in the hanging wire ability (McNamara et ...required in this field before this approach can be proposed in ...evaluated in vitro or in ...decrease in glycogen ...

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Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?

Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?

... from in vitro to in vivo studies, with generally promising conclusions, ...following in vitro digestion to earlier conducted in vivo incorporation into micelles from similar test ...

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Cellular immunotherapy in multiple myeloma : lessons from preclinical models

Cellular immunotherapy in multiple myeloma : lessons from preclinical models

... role in the prevention of autoimmunity and the regulation of immune ...decrease in Treg numbers was reported in MM patients, along with a defect in their ability to sup- press T-cell ...

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Immersive Analysis of 3D Multi-Cellular In-Vitro and In-Silico Cell Cultures

Immersive Analysis of 3D Multi-Cellular In-Vitro and In-Silico Cell Cultures

... tissue. In mouse, the common model system, this occurs around day ...GATA6 in the segmented nuclei [21], see Figure ...find in Table ...agent-based models [23], [24]. These models ...

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Immersive Analysis of 3D Multi-Cellular In-Vitro and In-Silico Cell Cultures

Immersive Analysis of 3D Multi-Cellular In-Vitro and In-Silico Cell Cultures

... tissue. In mouse, the common model system, this occurs around day ...GATA6 in the segmented nuclei [21], see Figure ...find in Table ...agent-based models [23], [24]. These models ...

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Cellular models for the screening and development of anti-hepatitis C virus agents.

Cellular models for the screening and development of anti-hepatitis C virus agents.

... hepatocytes in culture which makes extremely difficult, if not impossible, to investigate intracellular events such as nuclear translocation of proteins, or to visualize intracellular molecules or proteins, ...

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Examining the impact of multi-layer graphene using cellular and amphibian models

Examining the impact of multi-layer graphene using cellular and amphibian models

... is in contrast with some previous findings [ 22 , 35 ...cess) in neuronal rat cells exposed to pristine graphene (composed mainly of 3–5 layers) [ 36 ...stress in osteoblast and macrophage cell ...

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Modeling energy consumption in cellular networks

Modeling energy consumption in cellular networks

... aspects in energy consumption (see [1], [2], [3], [4] and references therein). In [5], some models are proposed for the activity of a single terminal and the resulting energy ...consumption. ...

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Cellular neuromodulation in artificial networks

Cellular neuromodulation in artificial networks

... Conclusions In this work, we use a high level view of a nervous system mechanism called cellular neuromodulation to improve artificial neural networks adaptive ...reported in this paper could be ...

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Anisotropic selection in cellular genetic algorithms

Anisotropic selection in cellular genetic algorithms

... (t) in the population ...as in standard GA, to a spatially structured one of the same size with synchronous updat- ing of the cells, the global selection pressure induced on the entire population is weaker ...

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In vitro cellular responses to silicon carbide nanoparticles: impact of physico-chemical features on pro-inflammatory and pro-oxidative effects

In vitro cellular responses to silicon carbide nanoparticles: impact of physico-chemical features on pro-inflammatory and pro-oxidative effects

... Fig. 3 Pro-inflammatory effect determined by the TNF-α production after a 24H incubation of cells with SiC nanoparticles. Doses were expressed in mass (A) or surface (B). Results are means of 3 independent ...

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Cartilage response to in vitro models of injury in combination with growth factor and antioxidant treatments

Cartilage response to in vitro models of injury in combination with growth factor and antioxidant treatments

... An in vitro model of joint injury that includes the combination of mechanical injury to cartilage and subsequent co-culture with excised joint capsule mimics specific changes o[r] ...

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