immune response and thymus.
The presentation of neuroendocrine self in the thymus: a necessity for an integrated evolution of the adaptive immune response and the neuroendocrine system.
... The immune system is a sensory organ able to respond to danger signals that are not detected by nervous ...The immune response is not autonomous but also regulated by central and peripheral ...
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The appearance of the thymus and the integrated evolution of adaptive immune and neuroendocrine systems
... tolerance and the development of ‘forbidden’ self-reactive immune clones ...in immune complexity during evolution is associated with a higher inci- dence of self-tolerance failures, most of them ...
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The thymus as an obligatory intersection between the immune and neuroendocrine systems: pharmacological implications
... that immune cells could express receptors susceptible to react against normal components of the ...Burnet and F Fenner proposed the principle of self/nonself discrimination as the cardinal point of ...
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Immune evasion, immunopathology and the regulation of the immune system.
... over-reacting immune response—or a response failing to make a distinction between self and non-self―potentially generates substantial fitness costs [27,28], one should expect natural selection ...
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Programing of the autoimmune diabetogenic response in the thymus during fetal and perinatal life
... Thymus and Autoimmunity In the early 2000s, the Heidelberg group of the late Bruno Kyewski reported the promiscuous gene expression (PGE) of tissue-restricted antigens (TRAs) in medullary (m) TECs ...
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The presentation of neuroendocrine self in the thymus: a necessity for an integrated evolution of the immune and neuroendocrine systems.
... the thymus Geenen candidiasis, and ectodermal dystrophy or autoim- mune polyglandular syndrome type ...thyroglobulin, and thyrotropin receptor (TSHR)) are also transcribed in TECs in normal ...37 ...
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Deciphering the immune response to respiratory pathogens - Role of programmed death-ligand 1
... developmentally and functionally distinct. Tregs can either be developed in the thymus (nTregs or tTregs) or induced in the periphery ...the thymus under the instruction of thymic APCs (cortical ...
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The thymus and the science of Self
... positive and avoided negative selection defines the capacity of the pool of mature T cells to respond to non-self- ...the thymus as an anatom- ical site where a relatively small number of T cells with tai- ...
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β2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection
... 4°C, and embedded in TissueTek optimal cutting temperature compound ...3050s and mounted on ...X100-Triton, and stained with anti-CD31 (553370; BD Phar- Mingen) and anti-TH (AB152; Millipore) ...
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Synthetic Rhamnolipid Bolaforms trigger an innate immune response in Arabidopsis thaliana
... medium and shock-frozen in liquid nitrogen 15, 60, or 180 min ...min and 30 μL of the supernatant were loaded on SDS-PAGE 12% gel for ...(v/v)) and incubated overnight at 4 °C with rabbit polyclonal ...
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Signaling in the immune response.
... structure, and are comprised of an ectodomain of leucine-rich repeats and an intracellular TIR (for Toll and Interleukin-1 receptor) domain that is also present in a number of plant disease ...
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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2
... BMDMs and cDCs triggers both TLR2 and TLR13 ...rRNA and is depen- dent on phagocytosis and endosomal ...TLR2 and the endo- somal TLR recognition pathway are not redundant in vivo: mice ...
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Voyage[s] à travers le thymus
... Mon équipe de recherche au GIGA de l'ULg a contribué à mettre au jour un phénomène essentiel de la vie qui est apparu avec le premier thymus il y a environ 450 millions d'années chez les poissons cartilagineux ...
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Th17-Immune Response in Patients With Membranous Nephropathy Is Associated With Thrombosis and Relapses
... Th2-type immune response with increased IL-4 levels ( 35 – 37 ) using real time ...al. and Roccatello et ...(n=25 and n=17, respectively) at diagnosis and an increasing level of these ...
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The cellular immune response of the pea aphid to foreign intrusion and symbiotic challenge
... low immune defenses. However, its immune components are largely undescribed, and notably, extensive characterization of circulating cells has been ...spherulocytes and wax ...Plasmatocytes ...
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The complex relationship between MITF and the immune system: a Melanoma ImmunoTherapy (response) Factor?
... status and intratumor heterogeneity Tumor cells are genetically unstable, displaying the accu- mulation of somatic mutations in their genome, which is believed to increase the likelihood of immunogenic neoan- ...
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Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
... antigen and by its co-administration with an ...events and safety ...humoral and cellular immune responses with minimal systemic production of inflammatory ...nanoparticles and admixed ...
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A model for establishment, maintenance and reactivation of the immune response after vaccination against Ebola virus
... (a) Ab(t) (b) B cells Figure 6: Simulation of (MSL) for vaccination group Ad26/MVA D57 with a booster dose of Ad26.ZEBOV one year after the first dose (day 360). In (a) the obtained log 10 - transformed antibody ...
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Effect of housing hygiene conditions and feed intake on specific and inflammatory immune response, bacterail cecal fermentation and survival of rabbits
... conditions and feed intake on specific and inflammatory immune response, bacterail cecal fermentation and survival of rabbits Sylvie Combes, ...
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Effect of infection by Plasmodium falciparum on the melanization immune response of Anopheles gambiae.
... the immune system— antibacterial defense and melanization—is positive rather than negative in a natural population of ...resistance and bead melanization would imply in our study that the mosquitoes ...
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