Imaging Genetics
Multilevel Modeling with Structured Penalties for Classification from Imaging Genetics data
... 4 Conclusion In this paper, we developed a novel approach to integrate genetic and brain imaging data for prediction of disease status. Our multilevel model takes into account potential interactions between genes ...
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Susceptibility of brain atrophy to TRIB3 in Alzheimer’s disease, evidence from functional prioritization in imaging genetics
... the imaging-genetics association patterns could be modulated by state-specific factors throughout the development of the disease [41], the heterogeneity of the MCI label is likely to lead to the inclusion ...
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Network regularization in imaging genetics improves prediction performances and model interpretability on Alzheimers's disease
... Terms— Imaging-Genetics, Networks, Structured constraints, Generalized Canonical Correlation Analysis ...that imaging en- dophenotypes stand as proxies to disease status and evolution, that can be ...
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A study of feasibility for genome-wide haplotype association of complex traits in imaging genetics
... Abstract— Imaging-genetics cohorts allow to find associations be- tween genotyped variants and brain imaging ...of genetics and environment in the brain characteristic variance observed in ...
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Contribution of imaging-genetics to overall survival prediction compared to clinical status for PCNSL patients
... Index Terms— Survival analysis, imaging genetics, MRI, Brain Tumor 1. INTRODUCTION Primary CNS lymphoma (PCNSL) is a diffuse large B-cell lymphoma (DLBCL), occurring in the brain and that never spreads to ...
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An imaging-genetic study of the asymmetries in the temporal lobe structures : association of these human-specific markers of development with genetics
... to genetics likely play a role in these ...in imaging genetics with a sample size above 10,000 subjects were conducted on the brain sulcal ...In imaging-genetics, previous GWAS with ...
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Design of a genetics database for medical research
... FOREIGN KEY (segment_2) REFERENCES GenSeg, FOREIGN KEY (units) REFERENCES UnitsDict (_code), FOREIGN KEY (owner) REFERENCES Contact. CREATE TABLE GenSegallLoc OF TYPE GenSeg-allLoc[r] ...
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Computational ghost imaging versus imaging laser radar for three-dimensional imaging
... ghost imaging could be mitigated to some degree, however, by the use of compressed-sensing techniques, which enable many fewer pulses to suffice for ghost-image ...ghost imaging done in reflection [ 27 ], ...
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[Genetics of asthma and atopy: how many genes?]
... A côté des très nombreuses études de gènes candidats, des efforts considérables ont été faits ces 10 dernières années pour localiser des régions chromosomiques pouvant contenir des gène[r] ...
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Congenital Microcoria: Clinical Features and Molecular Genetics
... Near the root, the anterior border layer, stroma, and bilayer epithelium of the iris form finger-shaped processes and become the ciliary body, the anterior and posterior epithelium lay[r] ...
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Genetics and mechanisms leading to human cortical malformations
... resonance imaging (MRI) images of patients with different brain cortical malformations are shown: Control, cobblestone lissencephaly (COB-LIS), periventricular heterotopia (PVH), subcortical band heterotopia ...
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Parasexuality and mosaic aneuploidy in Leishmania: alternative genetics
... Thus, within the cell population of a Leishmania strain, each of the ten studied chromosomes, in every cell, may be present in two or more ploidy states, that is, mo[r] ...
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Forests of hierarchical latent models for association genetics
... the observed variables (OVs) are often sufficient to describe their joint distribution, sometimes, additional unobserved variables, also named latent variables (LVs), have a role to play. In this context, hierarchical ...
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OryGenesDB: a database for rice reverse genetics
... OryGenesDB comes with a dedicated toolbox specifically designed for reverse genetics applications. The set of user friendly interfaces, complementary to GGB tools, developed for OryGenesDB provides the user with ...
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en fr Human genetics of male infertility Génétique de l'infertilité masculine
... Conclusions and perspectives Human genetics of male infertility 123 In the presented study, we identified recessive autosomal mutations that impair human male fertility. In fact, by studying a consanguineous ...
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Can Body Fat Cause Aortic Stenosis?: Lessons From Genetics
... represent a major advance in our understanding of the biology and genetic architecture of central obesity. Whether central obesity is genetically asso- ciated with AS or AVR remains to be determined. Exploiting these new ...
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Translating the genetics of cystic fibrosis to personalized medicine
... PT ED domain (R) (9). CFTR has several functions acting primarily as a chloride channel and regulating several other apical ion channels. To date, almost 2,000 mutations have been identified and collected from the ...
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Host genetics predict clinical deterioration in HCV-related cirrhosis
... Our results showing an association between PNPLA3 non-CC genotype and risk of clinical deterioration in age, sex, and race-adjusted analysis is supported by a study showing an associatio[r] ...
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Population genetics of fungal diseases of plants
... Overall, the estimation of dispersal abilities of fungal pathogens using genetic markers is still disappointing because the assumptions underlying the models are often biologically unrealistic, and because estimations ...
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Genetics and Life Insurance in Canada: Points to Consider
... the Genetics and Society Project of the Université de Montréal, Genome Canada projects (Quebec and Ontario) and in the INHERIT BRCAs Project (Interdisciplinary Health Re- search International Team on Breast Cancer ...
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