human mesenchymal stromal cell
Predicting in vitro human mesenchymal stromal cell expansion based on individual donor characteristics using machine learning.
... Background: Human mesenchymal stromal cells (hMSCs) have become attractive candidates for advanced medical cell-based ...as cell seeding density and available culture surface ...the ...
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Computational Modeling of Human Mesenchymal Stromal Cell Proliferation and Extra-Cellular Matrix Production in 3D Porous Scaffolds in a Perfusion Bioreactor: The Effect of Growth Factors.
... in cell growth and differentiation, as well as ensuring the supply of nutrients such as glucose and removal of metabolic waste such as lactate ( Martin et ...of cell expansion in 3D scaffolds, we need to ...
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Enhanced human bone marrow mesenchymal stromal cell adhesion on scaffolds promotes cell survival and bone formation.
... amorphous human bone [9,10] , animal derived bone matrices [13] or the coral exoskeleton [11] offer a similar structure to can- cellous bone and thus mimic the physiological bone tissue environ- ment [12] ...
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Cell specific differences between human adipose derived- and mesenchymal- stromal cells despite similar differentiation potentials.
... revealed cell specific differences at the phenotypic, mRNA, proteomic and functional levels ac- cording to their tissue ...two cell types have thus to be considered as different even though they can be ...
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Role of stromal-derived factor-1 in the hematopoietic-supporting activity of human mesenchymal stem cells.
... Discussion Although its primary role in hematopoiesis is to regulate homing and retention of stem cells in the bone marrow microenvironment (12), SDF-1 may be implicated in other processes. The effect of SDF-1 on the ...
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Expression of miRNA-210 in human bone marrow-derived mesenchymal stromal cells under oxygen deprivation
... supporting cell proliferation and preventing apoptosis ...in cell cycle- and proliferation-supportive mechanisms ...apoptotic cell death by a miRNA- 210/casp8ap2-dependent mechanism ...
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Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars
... multipotent mesenchymal stem or stromal cells ...skin cell types [ 9 ...marrow-derived human MSCs to prevent HTS in the rabbit model of ear scar [ 11 ...
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Role of miR‐466 in mesenchymal stromal cell derived extracellular vesicles treating inoculation pneumonia caused by multidrug‐resistant Pseudomonas aeruginosa
... 15 Human bone marrow mesenchymal stem cells (h-MSCs) were obtained from ...(L cell, L-929, derivative of Strain L) (Catalog #GNM28, ...the cell bank of the Chinese Academy of Sciences. ...
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Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo.
... xenografted human colon or prostate tumors ...of human cells, and cancer cells from diverse origins were used, although we demonstrated that ADSC-CM did not affect tumor cell viability in the same ...
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Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial
... [22–25]. Stromal cells have been shown to pos- sess immunomodulatory and antifibrotic properties, to protect cells from oxidative stress and apoptosis, and to stimulate prolif- eration and chondrogenic ...
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The use of mesenchymal stromal cells in solid organ transplantation
... T cell proliferation and func tion, inhibition of dendritic cell (DC) maturation, and induction of regulatory T cells (Tregs), DCs, and ...of human leukocyte antigen (HLA)-nonidentical MSCs is ...
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Mesenchymal stromal cells orchestrate follicular lymphoma cell niche through the CCL2-dependent recruitment and polarization of monocytes.: CCL2 AND FOLLICULAR LYMPHOMA CELL NICHE
... in human macrophages, the functional outcome of TLR and Notch interactions is more complex since Notch target genes feedback and attenuate TLR- induced cytokine production 41 ...addition, human adipose ...
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Mesenchymal Stem Cell Features of Ewing Tumors
... Su, A. I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K. A., Block, D., Zhang, J., Soden, R., Hayakawa, M., Kreiman, G., et al. (2004). A gene atlas of the mouse and human protein- encoding transcriptomes. Proc ...
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Immunoregulatory properties of clinical grade mesenchymal stromal cells: evidence, uncertainties, and clinical application.
... that human MSC source and culture conditions could modulate their capacity to inhibit immune response [33], indicating that a careful description of all culture parameters, as required for GMP-grade production, is ...
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Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration
... Various innate immune cells participate in the host-cell response to the implantation of CaP materials including mast cells, neutrophils, monocytes, macrophages, and multinucleated giant cells (MNGCs) ( 28 ). In ...
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A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation
... marrow-derived mesenchymal stem cells (BMSCs) are a connective tissue stem cell population that has been shown to modulate the immune system ...that human BMSCs secreted 760 pg/10 6 cells of sTNFR1 ...
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Clinical - scale expansion of mesenchymal stromal cells: a large banking experience
... MSC: mesenchymal stem/stromal cells; HLA: human leukocyte antigen; GVHD: graft-versus-host disease; CD: Crohn’s disease; RA: rheumatoid arthritis; ISCT: International Society of Cellular Therapy; ...
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Immunophenotyping Reveals the Diversity of Human Dental Pulp Mesenchymal Stromal Cells In vivo and Their Evolution upon In vitro Amplification
... Select 1X (Life Technologies) for amplification. Multiparametric Flow Cytometry The staining panel was designed by using 6 fluorochrome- conjugated antibodies, and the nucleic acid dye 7AAD (7-Amino- Actinomycin D, ...
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Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells.
... appearing at the beginning of the second passage at day 2, but later disappearing at day 7. This culture development is not discussed by Ben-David et al., but would seem to be at odds with their general in- terpretation ...
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Biopolymers-calcium phosphate antibacterial coating reduces the pathogenicity of internalized bacteria by mesenchymal stromal cells
... study. Human bone marrow (BM) samples were collected by aspiration from femoral necks of patients (aged between 40 and 70 years old) undergoing total hip ...fresh human umbilical cords were harvested after ...
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