Human embryonic stem cells (hESCs)
Preclinical safety studies of human embryonic stem cell‐derived retinal pigment epithelial cells for the treatment of age‐related macular degeneration
... pluripotent stem cell (PSC)-based reparative cell therapies are reaching the bed- side, there is a growing need for the standardization of studies concerning safety of the derived ...functional human ...
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Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
... murine embryonic stem cells (ESCs). Human ESCs (hESCs) invariably exhibit signs of X chromosome inactivation (XCI) and are considered developmentally more advanced than their murine ...the ...
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A gene expression signature shared by human mature oocytes and embryonic stem cells.
... including human cells, and to many cell types, including terminally differ- entiated cells such as granulocytes ...somatic cells towards ...teratocarcinoma cells or embryonic ...
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Global transcriptional profiling of neural and mesenchymal progenitors derived from human embryonic stem cells reveals alternative developmental signaling pathways.
... 3 phenotype in vitro follows sequential activation of gene networks and epigenetic changes that closely mimic events occurring in vivo during embryogenesis [1-5]. Identification of culture conditions that specifically ...
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Molecular signature of erythroblast enucleation in human embryonic stem cells
... recombinant human insulin [Incelligent SG, CellGen], 2 IU/mL heparin and 5% human plasma) in the presence of stem cell factor (SCF, 100 ng/mL), throm- bopoietin (TPO, 100 ng/mL), FLT3 ligand (FL, 100 ...
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A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas.
... hESC cells lines used, the control samples, the specific caveats of each transcriptome analysis technique and the statistical methodologies likely contribute to these disparities (see Supplemental Table ...(the ...
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Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined media
... since cells are stored in containers that are predisposed to leakage when plunged into liquid nitrogen ...[human embryonic SCs – RCM-1 cell line] and hiPSCs [human induced PSCs – dKips & ...
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Aseptic and automatable vitrification of human embryonic stem cells using defined media
... Proliferation curves after warming of slow frozen vs vitrified cells ¼ well of a 6-well plate. hESCs proliferation curves after SF or V.[r] ...
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Aseptic and automatable vitrification of human embryonic stem cells using defined media
... Proliferation curves after warming of slow frozen vs vitrified cells ¼ well of a 6-well plate. hESCs proliferation curves after SF or V[r] ...
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Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
... of stem cell plasticity, acting as epigenetic modifiers 10,11 ; however, much less is known on the role of ...control stem cell plasticity is crucial for understanding both early embryo development and ...
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en fr Human embryonic and neural stem cells : when PrP and APP are mixed Cellules souches embryonnaires et neurales humaines : quand la PrP et l'APP "s'en mêlent" ou "s’emmêlent"
... Cellules souches embryonnaires et neurales humaines : quand la PrP et l’APP ”s’en mêlent” ou ”s’emmêlent”.. Félicie Radreau.[r] ...
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Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
... these human ESCs and iPSCs that show differences in H3K4me3- and H3K27me3-modified ...undifferentiated cells may exert subtle effects on cells upon ...
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Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues.
... Figure 3. Sequential ChIP. Chromatin was extracted from 4 human ES cell lines and ChIP was performed sequentially using anti H3K4me3 and then anti-H3K27me3 antibodies. Please click here to view a larger version ...
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Cell-cell and cell-medium interactions in the growth of mouse embryonic stem cells
... of embryonic fibroblast cells 16, 17 (in a medium supplemented with bovine calf ...ES cells 26, 27 , though not in human ES cells 28 ...as human ES cells (see above ...
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A p38mapk-p53 cascade regulates mesodermal differentiation and neurogenesis of embryonic stem cells
... properties, embryonic stem cells (ESCs) have been proposed as cellular therapy for human ...differentiated cells and by the persistence of undifferentiated cells with a ...
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Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells
... CSC-like cells exhibited a capacity to differentiate (Figure 2d), especially after prolonged periods of tumour development (Supplementary Tables S1 and ...CSC-like cells (Figure ...CSC-like cells ...
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Genome-wide analysis of ATP-dependent chromatin remodeling functions in embryonic stem cells
... Heintzman, N.D., Hon, G.C., Hawkins, R.D., Kheradpour, P., Stark, A., Harp, L.F., Ye, Z., Lee, L.K., Stuart, R.K., Ching, C.W., et al. (2009). Histone modifications at human enhancers reflect global ...
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Differentiable PKC activation on pacemaking activity of cardiomyocytes derived from mouse embryonic stem cells
... pacemaker cells into the SA node to induce ...including embryonic stem cells (ESCs) [40] and induced pluripotent stem cells (iPSCs) ...ESCs cells are derived from the ...
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Control of the Embryonic Stem Cell State
... pluripotent stem cells (iPSCs) have been generated from a broad range of murine and human somatic cells by using forced expression of Oct4, Sox2, and other transcription factors ( Hanna et ...
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Embryonic stem cell markers expression in cancers.
... Cancer stem cells refer to a subset of tumor cells that has the ability to self-renew and generate tumor heterogeneity [3; 4; ...ES cells and germ cells. Rare cells that express ...
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