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hormone-dependent breast cancer

Effects of neonicotinoids on promoter-specific expression and activity of aromatase: Implications for the development of hormone-dependent breast cancer

Effects of neonicotinoids on promoter-specific expression and activity of aromatase: Implications for the development of hormone-dependent breast cancer

... In hormone-dependent breast cancer, the overproduction of estrogen is associated with an inhibition of normal ...vitro breast cancer model that allows us to determine this unique ...

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Breast cancer: Do contaminants conspire with tumors?

Breast cancer: Do contaminants conspire with tumors?

... for breast cancer are able to recreate the particular interactions of the hormone-dependent cancer, whether cellular or animal models, since they are often too ...of ...

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Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models

Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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Previous oral contraceptive use and breast cancer risk according to hormone replacement therapy use among postmenopausal women.

Previous oral contraceptive use and breast cancer risk according to hormone replacement therapy use among postmenopausal women.

... the breast cancer incidence ...of breast cancer in first-degree ...benign breast disease were derived from the questionnaire returned closest to the date of ...

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Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor β1 Are Inversely Associated with Survival in Primary Breast Cancer

Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor β1 Are Inversely Associated with Survival in Primary Breast Cancer

... BC signaling and progression is also influenced by the complex interplay between NR, their transcriptional coactivators, and corepressors that also have prognostic significance [ 27 ]. Among the transcriptional ...

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Development of a multi-gene PCR assay for the prediction of the response to hormone therapy in breast cancer

Development of a multi-gene PCR assay for the prediction of the response to hormone therapy in breast cancer

... Two ER molecules have been identified, namely ER-alpha (ER-α) and ER-beta (ER- β) 30 . The key functional domains in these receptors are the C or DNA-binding domain, which binds with high affinity and specificity to ...

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Precision medicine for metastatic breast cancer.

Precision medicine for metastatic breast cancer.

... the development of precision medicine that involves multi- plex molecular analyses to identify molecular mechanisms of cancer progression in each individual in order to improve treatment. In the following review, ...

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Breast cancer screening: Impact on care pathways

Breast cancer screening: Impact on care pathways

... French Cancer Cohort data, 24 000 women having undergone a bilateral mammogram and diag- nosed with breast cancer were identified in ...whose cancer was diagnosed following a mammogram car- ...

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Signaling pathway switch in breast cancer.

Signaling pathway switch in breast cancer.

... in breast cancer in NGS studies [1-4]; they are probably not directly targeted (yet, we have recently found rare mutations and deletions of the FOXO3 gene; Cornen et ...

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ELP3 links tRNA modification to IRES-dependent translation of LEF-1 to promote metastasis in breast cancer

ELP3 links tRNA modification to IRES-dependent translation of LEF-1 to promote metastasis in breast cancer

... in breast cancer cells did not lead to any increase in pPERK-related UPR pathway, nor to differences in the expression of the canonical transla- tion initiation proteins ...

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Breast cancer and serum organochlorine residues

Breast cancer and serum organochlorine residues

... palpable breast mass or mammographic abnormality underwent a biopsy, and from this initial group, 159 women ...from breast cancer and hospitalised for a mastectomy or tumourectomy were considered as ...

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SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

... adhesion, we hypothesized that the balance between RhoA and Rac1 could be a mediator of the SDF-1α ef- fect. We used the cell-sorting gate set-up in Fig. 2a to separate MDA-MB231 after a co-culture of 2 or 5 days with ...

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Title: Estrogen-progestagen menopausal hormone therapy and breast cancer: does delay from menopause onset to treatment initiation influence risks?

Title: Estrogen-progestagen menopausal hormone therapy and breast cancer: does delay from menopause onset to treatment initiation influence risks?

... 14. Collins JA, Blake JM, Crosignani PG: Breast cancer risk with postmenopausal hormonal treatment. Hum Reprod Update 11:545-560, 2005 15. Riboli E, Hunt KJ, Slimani N, et al: European Prospective ...

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The apoptosis inhibitor Bcl-xL controls breast cancer cell migration through mitochondria-dependent reactive oxygen species production

The apoptosis inhibitor Bcl-xL controls breast cancer cell migration through mitochondria-dependent reactive oxygen species production

... Bcl-xL fosters electron transport chain activity and mitochondrial ROS production Cytoskeleton remodeling is critical for cell migration(31,32) and closely depends on intracellular levels of ROS, which are mainly ...

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Breast cancer subtypes and screening mammography sensitivity

Breast cancer subtypes and screening mammography sensitivity

... for breast cancer and we have a good representation of most cases that arise in the Quebec City ...all cancer cases diagnosed in screening participants of the province of Québec following a reference ...

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Separate and combined analysis of successive dependent outcomes after breast-conservation surgery: recurrence, metastases, second cancer and death.

Separate and combined analysis of successive dependent outcomes after breast-conservation surgery: recurrence, metastases, second cancer and death.

... power to such an extent that the associations of some prognostic factors with any event were revealed (ex: histological tumor size in Table 4). No separate analysis was able to do this. Since the risk of any recurrence ...

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Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche

Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche

... Our findings of the tumor-promoted mesenchymal phenotype in ECs Mes might partly explain the molecular mechanisms that govern ECs plasticity. Interestingly, our transcriptomics data while confirming mesenchymal traits, ...

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On Data-Preparation Efficiency Application on Breast Cancer Classification

On Data-Preparation Efficiency Application on Breast Cancer Classification

... keywords: deep learning, convolutional neural networks, data prepa- ration, information metrics, Breakhis 1 Introduction Affecting one in eight women in the world, breast cancer is one of the most com- mon ...

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Cancer-associated adipocytes promotes breast tumor radioresistance.

Cancer-associated adipocytes promotes breast tumor radioresistance.

... . Cancer is a tissue-based disease in which malignant cells interact dynamically with multiple normal cell types such as fibro- blasts, adipocytes, infiltrating immune cells and endothelial cells within the context ...

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Prognostic impact of hormone receptor- and HER2-defined subtypes in inflammatory breast cancer treated with high-dose chemotherapy: a retrospective study

Prognostic impact of hormone receptor- and HER2-defined subtypes in inflammatory breast cancer treated with high-dose chemotherapy: a retrospective study

... risk breast cancer (defined by massive lymph node involvement) indicated a possible OS benefit from HDC in patients harboring hormonal or HER2-negative ...

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