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high throughput sequencing

Compression of Structured High-Throughput Sequencing Data

Compression of Structured High-Throughput Sequencing Data

... General Compression Benchmark We evaluated the H and H+T approaches against general compression approaches when storing HTS alignment data. Table 1 Figure 1. Structured Data Compression Techniques. We present the ...

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High-Throughput Sequencing of Transposable Element Insertions Suggests Adaptive Evolution of the Invasive Asian Tiger Mosquito Towards Temperate Environments

High-Throughput Sequencing of Transposable Element Insertions Suggests Adaptive Evolution of the Invasive Asian Tiger Mosquito Towards Temperate Environments

... | High-throughput TE insertion genotyping The presence/absence of insertions of five TE families was genotyped in an initial number of 140 individuals using a combination of family- specific PCR and ...

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Virus Detection by High-Throughput Sequencing of Small RNAs: Large-Scale Performance Testing of Sequencing Analysis Strategies

Virus Detection by High-Throughput Sequencing of Small RNAs: Large-Scale Performance Testing of Sequencing Analysis Strategies

... by High-Throughput Sequencing of Small RNAs: Large-Scale Performance Testing of Sequence Analysis Strategies Sebastien Massart, † Michela Chiumenti, Kris De Jonghe, Rachel Glover, Annelies Haegeman, ...

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GECKO is a genetic algorithm to classify and explore high throughput sequencing data

GECKO is a genetic algorithm to classify and explore high throughput sequencing data

... recently high throughput sequencing (HTS), have considerably advanced knowledge of disease etiology and classification 1 – 3 ...RNA sequencing data 4 and would be impossible to implement for ...

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Reference-free compression of high throughput sequencing data with a probabilistic de Bruijn graph

Reference-free compression of high throughput sequencing data with a probabilistic de Bruijn graph

... for both data storage and transmission. This triggered the need for more efficient methods than general purpose compression tools, such as the widely used gzip method. Results: We present a novel reference-free method ...

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Illuminating an Ecological Blackbox: Using High Throughput Sequencing to Characterize the Plant Virome Across Scales

Illuminating an Ecological Blackbox: Using High Throughput Sequencing to Characterize the Plant Virome Across Scales

... Montpellier University, Montpellier, France, 5 Department of Plant Biology and Graduate Program in Ecology, Evolution and Behavior, Michigan State University, East Lansing, MI, United States, 6 Laboratory of Virology, ...

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Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing

Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing

... in high-throughput sequencing will allow the detection of clones at lower concentrations than is pos- sible with conventional techniques in the study of V(D)J ...“repertoire sequencing” ...

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Time-lapse imaging of molecular evolution by high-throughput sequencing

Time-lapse imaging of molecular evolution by high-throughput sequencing

... low-throughput sequencing re- quires significant enrichment of a few sequences in the final ...used. High-throughput sequencing (HTS) technologies have been recently proposed to address ...

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Mapping of quantitative trait Loci underlying cold tolerance in rice seedlings via high-throughput sequencing of pooled extremes

Mapping of quantitative trait Loci underlying cold tolerance in rice seedlings via high-throughput sequencing of pooled extremes

... and sequencing A segment of fresh leaf ...2000 sequencing platform. All raw high- throughput sequencing data have been deposited in the SRA database with accession number ...

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High-throughput sequencing of multiple amplicons for barcoding and integrative taxonomy

High-throughput sequencing of multiple amplicons for barcoding and integrative taxonomy

... High-throughput sequencing of multiple amplicons for barcoding and integrative taxonomy Perrine Cruaud 1 , Jean-Yves Rasplus 1 , Lillian Jennifer Rodriguez 1,2 & Astrid Cruaud 1 Until now, the ...

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Marine holobiont in the high throughput sequencing era

Marine holobiont in the high throughput sequencing era

... zooxanthella associated corals, this concept expanded much further after the emergence of High-Throughput Sequencing and associated progresses in metabarcoding and metagenomics. Holobionts – defined ...

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High-throughput Sequencing of a 4.1 Mb Linkage Interval Reveals FLVCR2 Deletions and Mutations in Lethal Cerebral Vasculopathy

High-throughput Sequencing of a 4.1 Mb Linkage Interval Reveals <i>FLVCR2</i> Deletions and Mutations in Lethal Cerebral Vasculopathy

... For Peer Review High-throughput Sequencing of a 4.1 Mb Linkage Interval Reveals FLVCR2 Deletions and Mutations in Lethal Cerebral Vasculopathy Sophie Thomas 1,2 , Ferechté Encha-Razavi 1,2,3 , ...

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Molecular detection and characterization of duck respiratory viruses using unbiased high-throughput sequencing

Molecular detection and characterization of duck respiratory viruses using unbiased high-throughput sequencing

... Pools of ten swabs were put together to construct libraries. A total of 10 flocks of Peking ducks or Muscovy ducks were sampled. The preparation of specimens for deep sequencing was performed as previously ...

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A Primer on the Analysis of High-Throughput Sequencing Data for Detection of Plant Viruses

A Primer on the Analysis of High-Throughput Sequencing Data for Detection of Plant Viruses

... nanopore sequencing-based platforms, potentially facilitating on-site HTS analysis of samples, we will need faster and more memory-efficient analysis approaches to enable rapid data analysis, potentially away from ...

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Propidium monoazide (PMA) and ethidium bromide monoazide(EMA) improve DNA array and high-throughput sequencing ofporcine reproductive and respiratory syndrome virus identification

Propidium monoazide (PMA) and ethidium bromide monoazide(EMA) improve DNA array and high-throughput sequencing ofporcine reproductive and respiratory syndrome virus identification

... with the same superscript number must be compared only together. DNA array probes relative intensity from A) lung tissue homogenates spiked 707. with PRRSV (5,000 TCID50/mL), B) lung ti[r] ...

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Gene Capture Coupled to High-Throughput Sequencing as a Strategy for Targeted Metagenome Exploration

Gene Capture Coupled to High-Throughput Sequencing as a Strategy for Targeted Metagenome Exploration

... next-generation sequencing (NGS) technologies recover genetic materials from en- vironmental samples without the preparation of meta- genomic clone ...higher throughput and lower costs than other ...

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Study of bacterial populations from oligotrophic soil ecosystems using high throughput sequencing technologies

Study of bacterial populations from oligotrophic soil ecosystems using high throughput sequencing technologies

... have high levels of nutrients as well as surface layers composed of a variety of mineral complexes, creating oligotrophic niches for bacterial communities, which depend on mineral weathering for their growth and ...

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UMD-Predictor: A High-Throughput Sequencing Compliant System for Pathogenicity Prediction of any Human cDNA Substitution

UMD-Predictor: A High-Throughput Sequencing Compliant System for Pathogenicity Prediction of any Human cDNA Substitution

... Received 9 July 2015; accepted revised manuscript 11 January 2016. Published online 4 February 2016 in Wiley Online Library (www.wiley.com/humanmutation). DOI: 10.1002/humu.22965 ABSTRACT: Whole-exome sequencing ...

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Current impact and future direction of High Throughput Sequencing in plant virus diagnostics: the drivers of COST Action FA1407

Current impact and future direction of High Throughput Sequencing in plant virus diagnostics: the drivers of COST Action FA1407

... 2 NGS & Viruses Etiology Viral ecology Plant-virus interaction Plant resistance Viral population genetics Taxonomy Current impact on R&D?. Expected impact on diagnostics?[r] ...

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BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data

BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data

... Next-generation sequencing technologies provide an opportunity to identify CNA regions with unprece- dented ...whole-genome sequencing data for samples with matched ...

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