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Hepatitis C (HCV)

MCI-Shirley, Hepatitis C & Me

MCI-Shirley, Hepatitis C & Me

... According to a recent class action lawsuit fi led in federal court, 1 “Hepatitis C affl icts over 1,500 of the Massachusetts Department of Correction’s 10,000 prisoners” (McGovern, 2015). Sadly, the Department of ...

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Development of hepatitis C virus vaccines: challenges and progress.

Development of hepatitis C virus vaccines: challenges and progress.

... J.Biol.Chem.281(27), 18285-18295 (2006). 41. Dreux M and Cosset FL. The scavenger receptor BI and its ligand, HDL: partners in crime against HCV neutralizing antibodies. J Viral Hepat.14 Suppl 1, 68-76 (2007). 42. Zeisel ...

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Rheumatologic Manifestations of Hepatitis C Virus Infection

Rheumatologic Manifestations of Hepatitis C Virus Infection

... Hepatitis C virus and sicca syndrome Sicca symptoms of either the mouth or eyes have been reported in 10-30% of HCV infected patients. Conversely, less than 5% of patients with a defined Sjögren’s syndrome are ...

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Infection of Human Liver Myofibroblasts by Hepatitis C Virus: A Direct Mechanism of Liver Fibrosis in Hepatitis C.

Infection of Human Liver Myofibroblasts by Hepatitis C Virus: A Direct Mechanism of Liver Fibrosis in Hepatitis C.

... However, HCV infection does not consistently induce marked inflammation [ 6 ], particu- larly in fibrosing cholestatic hepatitis C, a highly aggressive course that can occur after liver transplantation, when ...

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Hepatitis C virus-microelimination program and patient trajectories after hepatitis C virus cure in an outpatient HIV clinical unit

Hepatitis C virus-microelimination program and patient trajectories after hepatitis C virus cure in an outpatient HIV clinical unit

... with hepatitis C virus (HCV) infection are overrepresented in the healthcare system due to various individual and contextual circumstances, including comorbidities and socioeconomic marginalization ...chronic ...

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Knowledge Discovery in Hepatitis C Virus Transgenic Mice

Knowledge Discovery in Hepatitis C Virus Transgenic Mice

... 2 The Research Problem Hepatitis C virus (HCV) constitutes a major cause of chronic liver disease around the world. Approximately 200 million people worldwide are infected with HCV [4, 10, and 15]. The development ...

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Cost-effectiveness model for sofosbuvir in chronic hepatitis C

Cost-effectiveness model for sofosbuvir in chronic hepatitis C

... 12. Grishchenko M, Grieve RD, Sweeting MJ et al. Cost-effectiveness of pegylated interferon and ribavirin for patients with chronic hepatitis C treated in routine clinical practice. Int J Technol Assess Health ...

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Neutralizing antibodies in hepatitis C virus infection.

Neutralizing antibodies in hepatitis C virus infection.

... Abstract Hepatitis C virus (HCV) is a major cause of hepatitis ...chronic hepatitis which can then progress to liver cirrhosis and hepatocellular ...

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Hepatitis C Therapy in Renal Patients: Who, How, When?

Hepatitis C Therapy in Renal Patients: Who, How, When?

... on Hepatitis C Outcomes Several studies have demonstrated that dialysis is associated with an increased risk of all-cause and liver-related mortality [ 41 – 43 ...adaptation. Hepatitis C treatment has long ...

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Evidence that hepatitis C virus genome partly controls infection outcome

Evidence that hepatitis C virus genome partly controls infection outcome

... by hepatitis C virus (HCV) leads to one of two outcomes; either the infection resolves within approximately 6 months or the virus can persist indefi- ...the Hepatitis C Incidence and Transmission Study in ...

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Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

... chronic hepatitis C (CHC) patients the immune response fails to eradicate the virus due to impaired T cell and antibody responses, and little antiviral efficacy of IFN-stimulated genes (ISGs) ...

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Chronic hepatitis C virus infection, a new cardiovascular risk factor?

Chronic hepatitis C virus infection, a new cardiovascular risk factor?

... manifestations. Hepatitis C virus (HCV) infection has been associated to a very large number of extrahepatic manifestations in various tissues and organs ...

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Cholesterol uptake and hepatitis C virus entry.

Cholesterol uptake and hepatitis C virus entry.

... HCV: Hepatitis C virus; FDA: US Food and Drug Administration; NPC1L1: Niemann-Pick C1-like 1; HCVcc: cell culture-derived HCV; HCVpp: HCV pseudoparticles; GAG: glycosaminoglycans; SR-BI: scavenger receptor BI; ...

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Hepatitis C and the California Prisoner

Hepatitis C and the California Prisoner

... Hepatitis C is a blood borne pathogen and can spread quickly in a community of intravenous drug users. High risk behaviour like tattooing and unprotected sex can lead to transmission. The fact that two-thirds of ...

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Hepatitis C virus-related vasculitis

Hepatitis C virus-related vasculitis

... Abstract Cryoglobulinemic vasculitis (CryoVas) is a small-to-medium vessel systemic vasculitis caused by the deposition of mixed cryoglobulins and immune complexes. Clinical spectrum of CryoVas ranges from mild symptoms ...

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Hepatitis C virus entry.

Hepatitis C virus entry.

... of hepatitis C virus entry for pathogenesis of liver disease and antiviral therapy ...of hepatitis C virus binding and entry factors Hepatitis C virus (HCV) is a small, enveloped RNA virus that ...

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Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C.: NK cells in chronic hepatitis C and hepatitis B

Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C.: NK cells in chronic hepatitis C and hepatitis B

... mediated liver damage. J Exp Med 2007;204:667-680. [13] Lin AW, Gonzalez SA, Cunningham- Rundles S, Dorante G, Marshall S, Tignor A, et al. CD56(+dim) and CD56(+bright) cell activation and apoptosis in hepatitis C ...

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Extrahepatic manifestations of chronic hepatitis C virus infection

Extrahepatic manifestations of chronic hepatitis C virus infection

... Asian studies suggest the association between HCV infection and an increased risk of carotid- artery plaques and carotid intima-media thickening, independently of classical card[r] ...

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In Situ Hepatitis C NS3 Protein Detection Is Associated with High Grade Features in Hepatitis C-Associated B-Cell Non-Hodgkin Lymphomas

In Situ Hepatitis C NS3 Protein Detection Is Associated with High Grade Features in Hepatitis C-Associated B-Cell Non-Hodgkin Lymphomas

... Immunostaining with HCV NS3 antibody (Novocastra Lab) was performed in order to detect the in situ expression of HCV in 37 cases with enough or adequate material. For the other cases, either the block was too tiny for a ...

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Correlates of protective immunity against hepatitis C virus

Correlates of protective immunity against hepatitis C virus

... Our results showed that protection from chronicity upon reinfection was associated with an increased magnitude and breadth of the HCV-specific polyfunctional CD4 and CD8 T-c[r] ...

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