Hepatitis B Virus (HBV)
Hepatitis B surface antigen quantification as a predictor of seroclearance during treatment in HIV-hepatitis B virus coinfected patients from Sub-Saharan Africa
... HIV-hepatitis B virus (HBV) co-infected patients were included in ...having hepatitis B surface antigen (HBsAg)-seroclearance] during each time-interval has been ...
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Self-reported patient history to assess hepatitis B virus serological status during a large screening campaign
... assessing hepatitis B virus (HBV) status in clinical settings, it is unclear whether self- reports on vaccination history and previous HBV-test results have any diagnostic ...were hepatitis ...
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Correlation of serum hepatitis B core-related antigen with hepatitis B virus total intrahepatic DNA and covalently closed circular-DNA viral load in HIV–hepatitis B coinfection
... HBV, hepatitis B virus; HBeAg, hepatitis B “e” antigen; qHBcrAg, quantified hepatitis B core-related antigen; qHBsAg, quantified hepatitis B surface antigen; ...
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Performance of the Cobas AmpliPrep/Cobas TaqMan real-time PCR assay for hepatitis B virus DNA quantification.
... INTRODUCTION The presence of hepatitis B virus (HBV) DNA in peripheral blood is a reliable marker of active HBV replication. HBV DNA quantification is the best method for monitoring the level of HBV ...
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Early-onset liver cancer in South America associates with low hepatitis B virus DNA burden
... Hepatitis B virus DNA and RNA quantifications. HBV DNA was quantified by qPCR from 100 ng Qubit-measured genomic DNA extracted from HCC/NTL tissues. Assays were performed in a CFX96 ™ Real-Time PCR ...
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CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
... Hepatitis B virus (HBV) chronically infects over 250 million people worldwide. Chronically infected individuals are at an increased risk for deadly complications, including cirrhosis, end-stage liver ...
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Meta-transcriptomic identification of hepatitis B virus in cerebrospinal fluid in patients with central nervous system disease
... PCR, hepatitis B virus (HBV) was detected in the CSF of two patients diagnosed with CNS ...genotypes B and C and clus- tered with other viruses of Asian ...the virus is likely to be ...
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Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic Hepatitis B virus infection
... monkey hepatitis virus (WMHV) (Lanford et al., 1998), woodchuck hepatitis virus (WHV) (Summers et ...squirel hepatitis virus (GSHV) (Marion et ...squirel hepatitis ...
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Association of Hepatitis B Core-Related Antigen and Antihepatitis B Core Antibody With Liver Fibrosis Evolution in Human Immunodeficiency Virus-Hepatitis B Virus Coinfected Patients During Treatment With Tenofovir
... HBcrAg, hepatitis B core-related antigen; HBeAg, hepatitis B e antigen; HBV, hepatitis B Virus; HIV, human immunodeficiency virus; LAM, lamivudine; N, total number ...
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100 kHz MAS Proton-Detected NMR Spectroscopy of Hepatitis B Virus Capsids
... University Hospital Freiburg, University of Freiburg, Freiburg, Germany We sequentially assigned the fully-protonated capsids made from core proteins of the Hepatitis B virus using proton detection ...
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Hepatitis B Virus Core Variants, Liver Fibrosis, and Hepatocellular Carcinoma
... Hepatitis B Virus Core Variants, Liver Fibrosis, and Hepatocellular Carcinoma.. Gaetan Ligat, Catherine Schuster, Thomas Baumert.[r] ...
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Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.
... archive for the deposit and dissemination of sci- entific research documents, whether they are pub- L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau ...
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Antiviral-resistant hepatitis B virus: can we prevent this monster from growing?
... wild-type virus in the presence of antiviral ...the virus but not enough to result in rapid suppression of HBV replication) and a low genetic barrier to resistance (marked decrease in susceptibility due to ...
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Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes
... Figure S3. Analysis and quantification of HBV DNA extracted from HBV infectious particles by PCR (related to Figure 4). A-B. HBV genomic DNA (rcDNA) was extracted from cell culture-derived HBV virions. Extraction ...
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Hepatitis B virus resistance to entecavir in nucleoside naïve patients: Does it exist?
... chronic hepatitis B remains a major clinical challenge ...chronic hepatitis towards its main complications including decompensation of liver cirrhosis and development of hepatocellular carcinoma ...
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Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs
... Recognition and uptake of virus by CLRs together with subsequent signalling cascades are decisive in the outcome of infection, yet the interaction of HBV with CLRs is largely unknown. As HBV hijacks DC subsets, ...
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Development of anti-hepatitis B surface (HBs) antibodies after HBs antigen loss in HIV-hepatitis B virus co-infected patients
... when virus is known to circulate at low levels below detection thresholds of most conventional PCR assays ...of hepatitis B core antigen-specific CD8+ T cells, associated with cell-mediated clearance ...
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Hepatitis B virus genotypes: a retrospective survey in Southwestern France, 1999-2004.: HBV genotypes in Southwestern France
... reported in France, Georgia, Germany, and Mexico, but not in Japan [7,26-28]. We found a strong correlation between HBV genotypes and the presumed mode of infection, but the latter may merely be a surrogate marker of ...
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Hepatitis B virus resistance to antiviral drugs: where are we going?
... Chronic hepatitis ; Antivirals ; Drug resistance ; entecavir ; tenofovir ; interferon Chronic hepatitis B therapy The ultimate goals of therapy for chronic hepatitis B (CHB) are to ...
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Comparison of the antiviral activity of adefovir and tenofovir on hepatitis B virus in HIV-HBV-coinfected patients.
... Karine Lacombe, Joël Gozlan, Anders Boyd, Pierre-Yves Boelle, Philippe Bonnard, Jean-Michel Molina, Patrick Miailhes, Caroline Lascoux-Combe,. Lawrence Serfaty, Fabien Zoulim, et al[r] ...
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