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Glucocorticoid receptors

Experience and activity-dependent control of glucocorticoid receptors during the stress response in large-scale brain networks

Experience and activity-dependent control of glucocorticoid receptors during the stress response in large-scale brain networks

... of glucocorticoid secretion rhythms, by chronic stress exposure, exaggerates the elimination of dendritic spines, most notably the new experience- associated pool but also a tiny fraction of the pre-existing pool ...

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TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

... Layal Maatouk 1 , Anne-Claire Compagnion 1 , Maria-Angeles Carrillo-de Sauvage 2 , Alexis-Pierre Bemelmans 2 , Sabrina Leclere-Turbant 3 , Vincent Cirotteau 1 , Mira Tohme 4 , Allen Beke 1 , Michaël Trichet 5 , Virginie ...

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Importance of glucocorticoid receptors in the physiopathology of Alzheimer's disease

Importance of glucocorticoid receptors in the physiopathology of Alzheimer's disease

... homeostasis. Dysregulation of this pattern of secretion has been described in several disease states (Lightman and Conway-Campbell, 2010). Therefore, we first investigated the integrity of the HPA axis in 4-month old ...

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Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression

Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression

... doi: 10.3389/fnins.2018.00739 Edited by: Jean-Michel Verdier, Université de Sciences Lettres de Paris, France Reviewed by: David Blum, INSERM U1172 Centre de Recherche Jean Pierre Aubert, France Emmanuel Planel, Laval ...

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Corticosteroid receptors adopt distinct cyclical transcriptional signatures

Corticosteroid receptors adopt distinct cyclical transcriptional signatures

... Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone- activated transcription factors that regulate major pathophysiologic ...both receptors ...

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en fr GILZ (Glucocorticoid-induced leucine zipper) role in polymorphonuclear neutrophil and inflammation resolution Rôle de GILZ (Glucocorticoid-induced leucine zipper) dans l’apoptose du polynucléaire neutrophile et la résolution de l’inflammation

... We found a negative correlation between gilz expression and PaO 2 /FiO 2 ratio close to statistical significance. This correlation suggests that hypoxemia could participate in gilz expression in blood neutrophils. ...

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Dependence receptors: mechanisms of an announced death.

Dependence receptors: mechanisms of an announced death.

... Several proapoptotic partners of dependence receptors have been identified (Table 1), but so far none of them emerge as a universal proapoptotic adaptor for dependence receptor-induced death. DIP13α, a candidate ...

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Ethylene receptors modulate fruit development and ripening

Ethylene receptors modulate fruit development and ripening

... of receptors have different roles in controlling fruit ripening with the early induced genes having a larger role in fruit ...other receptors that are up-regulated later in fruit ...

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Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine

Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine

... Decreased behavioral and post-synaptic responses to amphetamine observed in GR D1Cre mice were unlikely due to alterations in post-synaptic dopamine D1-mediated signaling as these mice showed similar responses to ...

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Implication de "Liver X Receptors" dans la physiopathologie des gonades

Implication de "Liver X Receptors" dans la physiopathologie des gonades

... Huang, The G-Protein-coupled bile acid receptor, Gpbar1 TGR5, negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activate[r] ...

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Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors.: Profiling of estrogen receptors environmental ligands

Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors.: Profiling of estrogen receptors environmental ligands

... thyroid or adrenal glands, bone and some regions of the brain. Although ERα and ERβ share similar mechanisms of action, several differences in the transcriptional abilities of each receptor, as well as distinct ...

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Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress

Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress

... Regulation of muscle mass by REDD1 We previously demonstrated that REDD1 deficiency is protective against skeletal muscle atrophy following gluco- corticoid treatment [ 32 ]. In contrast, we show here that REDD1 deletion ...

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Interactions between neurotensin receptors and G proteins.

Interactions between neurotensin receptors and G proteins.

... NT receptors and G proteins were suggested through pioneering works showing that NT induced inositol phosphate (InsP) production [1,22,70], inhibited cAMP formation [10], and that the "high affinity NT binding ...

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Genetic diversity of canine olfactory receptors.

Genetic diversity of canine olfactory receptors.

... Comparison of these two values (0.37 and 0.098) indicates an absence of strong selective constraint, resulting in greater diversification for the OR genes, as already observed for a smal[r] ...

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Activating and Inhibitory Receptors on Mast Cells

Activating and Inhibitory Receptors on Mast Cells

... The best example of an efficient therapeutic antibody that targets a ligand of mast cell receptors is anti-IgE. This humanized monoclonal anti-human IgE is directed against an epitope located in the binding site ...

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Molecular characterization of cortisol receptors in fish

Molecular characterization of cortisol receptors in fish

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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Heteromerization of human cytomegalovirus encoded chemokine receptors

Heteromerization of human cytomegalovirus encoded chemokine receptors

... in the presence of UL33 and UL78 was unlikely to be due to altered expression levels of the receptors, since they remained relatively stable under the different experimental conditions (see Figs. 5B, C, E & ...

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Adaptive β-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance

Adaptive β-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance

... The arrow indicates the start of CORT or VEH treatment (B) Pancreatic beta-cell fraction, (C) beta-cell mass, (D) islet density and (E) mean islet size were calculated by morphometrica[r] ...

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The riddle of the plant vacuolar sorting receptors.

The riddle of the plant vacuolar sorting receptors.

... It should be noted that in plants, in addition to the classical transport via Golgi pathway, some proteins and other molecules can apparently be stored for shorter or longer periods of time in endoplasmic ...

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Modulation of Oxytocin Receptors in Right Ventricular Hypertrophy

Modulation of Oxytocin Receptors in Right Ventricular Hypertrophy

... hypertension is unknown. We can speculate that the increased synthesis of these peptides in LV is associated with stretch of ventricles and increased plasma ANP and BNP levels observed in MCT-treated rats [Usui et al ...

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