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gene drive

Conservation demands safe gene drive

Conservation demands safe gene drive

... In 2016, New Zealand boldly announced a program to eliminate all its rats, possums, and stoats by 2050. These invasive species cause enormous damage to the New Zealand flora and fauna, with rats and possums also imposing ...

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Can a Population Targeted by a CRISPR-Based Homing Gene Drive Be Rescued?

Can a Population Targeted by a CRISPR-Based Homing Gene Drive Be Rescued?

... a drive, into which brake- carrying individuals are ...onto gene frequency changes, and we also develop a stochastic version of the ...of gene conversion for gene drive and brake ...

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Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks

Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks

... CRISPR gene drive has recently been proposed as a promising technology for population management, including in con- servation ...a gene drive is affected by different factors that depend on ...

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Current CRISPR gene drive systems are likely to be highly invasive in wild populations

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

... CRISPR-based gene drive systems are unlikely to efficiently invade wild populations due to drive-resistant alleles that prevent ...effective drive systems reported to date are likely to be ...

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A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

... virulence gene pairwise deletion matrices Given our ability to efficiently generate homozygous double-gene deletion mutants by mating, we scaled up our approach to create large pairwise gene deletion ...

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GENE DRIVE AND TRUST IN SCIENCE

GENE DRIVE AND TRUST IN SCIENCE

... It is commendable that the list of Guiding Principles for the spon- sors and supporters of Gene Drive Research (GPGDR) has been devel- oped. However, it must be noted that it is a voluntarily undertaken ...

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Building innovation ecosystems to drive carbon neutral sustainability goals

Building innovation ecosystems to drive carbon neutral sustainability goals

... another in clusters known as innovation ecosystems. According to the MIT IDE framework, four elements are necessary for the prosperous growth of an innovation ecosystem: capacity of inn[r] ...

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Predictive models of hard drive failures based on operational data

Predictive models of hard drive failures based on operational data

... hard drive disk of this company data ...the drive, the model of the drive, the capacity of the drive in bytes, a failure label that is at 0 as long as the drive is healthy and that is ...

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Magnetic Confinement Fusion - Plasma Theory: Heating and Current Drive

Magnetic Confinement Fusion - Plasma Theory: Heating and Current Drive

... can drive current in a relatively efficient ...current drive relies for the most part on the variation of the plasma collisionality with the energy of resonant ...current drive purpose, as long as ...

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GOToolBox: functional analysis of gene datasets based on Gene Ontology.

GOToolBox: functional analysis of gene datasets based on Gene Ontology.

... tasks: gene dataset creation, selection and fitting of ontology level (GO-Diet), statistical analysis of terms associated with gene sets (GO-Stats), GO-based gene cluster- ing (GO-Proxy), and ...

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Where we look when we drive: A multidisciplinary approach

Where we look when we drive: A multidisciplinary approach

... 6. Conclusion It appears from these examples that our contributions address three main issues. The first one is to improve the state of the art about “where we look when we drive”, which is known to be very task- ...

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Will blood drive volunteers be available in the future?

Will blood drive volunteers be available in the future?

... partners Will Blood Drive Volunteers Be Available In The Future? G. Lacroix¹, J. Charbonneau¹, F. Décary², F. Désilets¹, K. Hébert¹, N. Tran¹ ¹ National Institute of Scientific Research (INRS), Montreal, Canada - ...

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Spectral analysis of gene expression profiles using gene networks

Spectral analysis of gene expression profiles using gene networks

... the gene expression profiles of the studied samples is a second possible application of the spectral decomposition of expression profiles on the gene ...from gene expression data, or discriminating ...

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Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression

Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression

... these cells are produced in mec-3 mutants, but they do not dif- ferentiate as TRNs (13). Therefore, mec-3 acts as a typical ter- minal selector gene. UNC-86 is needed not only to produce touch cell lineages but ...

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Combined RF Current Drive and Bootstrap Current in Tokamaks

Combined RF Current Drive and Bootstrap Current in Tokamaks

... current drive (RFCD) and the bootstrap current in a consistent kinetic manner, we find synergistic effects in the total non- inductive current density in tokamaks ...Current drive efficiency is found to be ...

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Commande en Mode Dégradé d'un Drive avec Deux Machines 6 phases en Série

Commande en Mode Dégradé d'un Drive avec Deux Machines 6 phases en Série

... SYMPOSIUM DE GENIE ELECTRIQUE (SGE 2016) : EF-EPF-MGE 2016, 7-9 JUIN 2016, GRENOBLE, FRANCE Commande en Mode Dégradé d’un Drive avec Deux Machines 6 phases en Série Tiago José dos Santos Moraes 1 , Ngac Ky Nguyen ...

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Commande en Mode Dégradé d'un Drive avec Deux Machines 6 phases en Série

Commande en Mode Dégradé d'un Drive avec Deux Machines 6 phases en Série

... La REM (Représentation Energétique Macroscopique) consiste en une méthode de représentation par un schéma bloc, où chaque bloc possède le modèle mathématique d’un él[r] ...

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Intense Competition can Drive Selfish Explorers to Optimize Coverage

Intense Competition can Drive Selfish Explorers to Optimize Coverage

... Our main takeaway message is that optimal coverage is expected to emerge by a congestion policy which is defined by a “Judgment of Solomon” type of rule: If a single player attempts to e[r] ...

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What Factors Drive transport and Logistics Costs in Africa ?

What Factors Drive transport and Logistics Costs in Africa ?

... 17 Samuelson (1964)'s argument, which assumes that the lower the level of development the lower the price of non-tradables. In other words, the price of domestic transport and logist[r] ...

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Current Drive by Electron Bernstein Waves in Spherical Tori

Current Drive by Electron Bernstein Waves in Spherical Tori

... tion the density of power dissipated is P peak ≈ 6.1 MW m −3 . This leads to η peak ≈ 1.9. From the two panels in Fig. 6 we note that this is the con- ventional Fisch-Boozer scheme of current drive. The EBW ...

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