Formation de la bile
Influence of cell mechanics in embryonic bile duct lumen formation: insight from quantitative modeling
... initial bile duct lumen formation during embryogenesis exist, which so far remained largely ...developing bile ducts from embryonic mouse liver, these hypotheses were sharpened and data collected ...
40
Supramolecular hydrogels based on bile acids and their derivatives
... the formation of such gels are relatively weak supramolecular interactions such as hydrophobic interactions, hydrogen bonding, electrostatic attractions, and van der Waals ...on bile acids and their ...
147
Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions
... due to nonspecific symptoms, a lack of early biological markers, delayed diagnosis and metastasis formation. Patients diagnosed with advanced or metastatic disease are not eligible for surgery (85% of patients) ...
17
Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways
... Insulin tolerance test. Mice were fasted for 4 h and then challenged with insulin (1mU/g) by IP. Blood glucose concentrations were measured at regular time points, and blood samples were collected to determine insulin ...
12
Synthesis and characterization of main-chain bile acid-based degradable polymers
... the formation of the cycle because the protons on the double bond of cyclic monomer 3a became chemically ...the formation of the macrocycle is slightly hampered by the rotation of carbons a and b, and the ...
130
Évaluation prospective de la performance de l’aspiration de bile associée au brossage biliaire par CPRE dans le diagnostic des sténoses biliaires malignes
... Les cellules épithéliales biliaires matures sont également, via leur transformation, à l’origine de processus de cancérogénèse. En effet, les cholangiocarcinomes extra- hépatiques proximaux et distaux peuvent être issus ...
99
Polyamides and polyesters made of bile acids in the main chain
... Bile acids also possess several chiral centers. The modification of hydroxyl and carboxylic groups of bile acids can give rise to a diverse range of bile acid-based compounds. The carboxylic acid ...
102
Bile Acid Alters Male Mouse Fertility in Metabolic Syndrome Context.
... Glucose was measured on plasma upon manufacturer recommendations (Biomerieux 61269). Real-Time RT-PCR RNA from testis samples were isolated using Nucleospin RNA (Macherey-nagel, Hoerdt, France). cDNA were synthesized ...
15
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate
... Real-Time RT-PCR RNA from testis samples was isolated using Nucleospin RNA L (Macherey Nagel). cDNA was synthesized from total RNA with the MMLV reverse transcriptase and random hexamer primers (Promega). Real-time PCR ...
14
Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids as a Marker of Cholestatic Drug Potential
... BA mixtures after 24h-incubation. Preferential formation of taurine conjugates from the 3 BAs agrees with previous observations (Sharanek, et al., 2017). Major differences were observed in supernatant/cell ...
31
Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases
... into bile, which flows through the bile duct to the ...the bile and the gallbladder in many ...apical bile salt efflux pump (BSEP; ABCB11) and the multidrug resistant-associated protein 2 ...
25
Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
... Real-Time RT-PCR. RNA from liver or testis samples was isolated using Nucleospin RNA L (Macherey-nagel, Hoerdt, France). cDNA was synthesized from total RNA with the MMLV reverse transcriptase and random hex- amer ...
11
The effect of exercise training on cholesterol and bile acid metabolism in ovariectomized rats
... v experimental group was Ovx rats fed a high cholesterol diet (Ovx-Chol) that was compared, on one hand, to a group of Ovx rats fed a standard diet (Ovx-SD) to observe the effects of the diet and, on the other hand, ...
169
Bile acids induce apoptosis selectively in androgen-dependent and -independent prostate cancer cells
... Our observation that Bid is cleaved after treatment with LCA suggests that once caspase-8 is activated it would continue to cleave Bid, thereby initiating the intrinsic pathway of apoptosis. In fact, treatment of ...
17
The CMC-like behaviour of bile salts as probed by photoexcited Rose Bengal
... dihydroxy bile salts (NaCDC, NaDC, NaGDC and NaTDC) but PS was clearly smaller than BP for the trihydroxy bile salts (NaC, NaGC and NaTC) and their zwitterionic analogue ...dihydroxy bile salts, ...
24
The bile duct ligated rat : a relevant model to study muscle mass loss in cirrhosis
... Bile duct ligation-induced cirrhosis leads to decreased gastrocnemius muscle mass and circumference as well as altered muscle morphology Compared with control rats, BDL animals had decreased gastrocnemius mass ...
21
Magnesium affects spinach carotenoid bioaccessibility in vitro depending on intestinal bile and pancreatic enzyme concentrations
... micelles, bile salts de- crease the surface tension of the water-lipid interface, stabilizing emulsions (Hofmann & Mysels, 1987), giving them a negative ...of bile, similar to an earlier study (Wickham, ...
10
A bile acid transporter as a candidate receptor for hepatitis B and D virus entry.
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
2
Recombinant Bile Salt-Stimulated Lipase in Preterm Infant Feeding: A Randomized Phase 3 Study
... Pasteurization of donor milk to prevent transmission of pathogens is routine in most NICUs. A complication of this is the denaturation of heat labile bioactive proteins such as the bile salt-stimulated lipase ...
16
In vivo evidence for transintestinal cholesterol efflux in patients with complete common bile duct obstruction
... primary bile ducts; Mikael Croyal, Audrey Aguesse and Michel Krempf contributed to the Mass spectrometry analyses; Xavier Prieur and Eric Miraille revised the manuscript; Matthieu Pichelin designed the research ...
13