... Tripartite efflux pumps are among the main actors responsible for antibiotics resistance in Gram-negative ...MexEF effluxpump from Pseudomonas ...passive efflux mecha- nism of ...
... MmpS5/MmpL5 effluxpump and accounting for high resistance levels toward various TAC analogs ( Halloum et ...MmpS5/MmpL5 effluxpump machinery ( Halloum et ...
... multidrug efflux pumps conferring adaptive resistance to ...these efflux pumps also influences quorum ...MexEF-OprN effluxpump modulates quorum sensing through secretion of a signalling ...
... membrane, efflux transporters are organized as tripartite systems where MexB, the effluxpump located in the inner membrane, works in conjunction with MexA, a periplasmic protein, and OprM, an outer ...
... Based on this finding, we used IMP2 as a tool to make double mutants. Our data revealed that when TPO1, TPO2 and QDR3 are mutated in combination with IMP2, cells become extremely sensitive to bleomycin and polyamines, as ...
... 3. Nagano K, Nikaido H. 2009. Kinetic behavior of the major multidrug effluxpump AcrB of Escherichia coli. Proc Natl Acad Sci U S A 106:5854-5858. 4. Dewitt SK, Adelberg EA. 1962. The Occurrence of a ...
... of efflux pumps that belong to the Resistance-Nodulation-Cell-Division (RND) superfamily, with, as most studied members AcrAB-TolC tripartite system from ...tripartite effluxpump from Escherichia ...
... Abstract Despite recent advances in the treatment of colorectal cancer (CRC), tumor resistance is a frequent cause of chemotherapy failure. Therefore, new treatment options are needed to improve survival of patients with ...
... of efflux pumps from resistance nodulation division family As developed in the previous paragraph, efflux pumps from the RND family consist of three main ...since effluxpump work as a ...
... is assembled, MexB might adopt a conformation that allows the recruitment of substrate at a lower concentration than in the absence of OprM. The first in vitro reconstitution of a tripartite efflux pump is presented ...
... a pump inhibitor with a potential of targeting efflux systems in a wide panel of Gram-positive human pathogenic ...know pump substrates revealed at least two active compounds; chlorogenic acid with ...
... These results indicate that, in SN-38 resistant HCT116-SN50 xenografts, the combination of sorafenib plus irinotecan inhibits tumor cell proliferation and angiogenesi[r] ...
... [11] Eisele K., Zhang Z., Casey M. V., Gülich J., Schachenmann A. 1997 Flow analysis in a Pump Diffuser Part 1 : LDA and PTV Measurements of the Unsteady FlowTransactions of ASME, Journal of Fluids EngineeringVol. ...
... 7. Pump-probe scans for H21 in a 50 /50 mixture of argon and nitrogen, around the half revival of N 2 ...the pump–probe delay would allow an additional contrast ...
... D. Bigourd, C. Fourcade-Dutin and H. Maillotte are with the Institut FEMTO- ST, Département d’Optique, UMR 6174 CNRS-Université Bourgogne Copyright (c) 2018 IEEE representative of the spectral gain) is recorded with a ...
... The present contribution deals with the development of a magneto-active pump devoted to ventricular assist device. The actuator studied is a cylindrical linear switched reluctance motor equipped with a ...
... ‘peristaltic pump mechanism’ and the ‘functionally rotating ordered multidrug binding change mechanism’ 27,31 are very promising but not totally satisfactory for the definition of suitable physico- chemical ...
... damage pump internal parts and cause vibrations. Video of the pump cylinder was recorded for most of the ...the pump cylinder in tests with a period less than 4 ...the pump drive end internals ...
... 1 I NTRODUCTION Heart failure is one of the most common diseases in developed countries. Because the number of donor heart is limited, patients suffering from end-stage heart failure require mechanical circulatory ...
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