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Efflux pump

Xenon for tunnelling analysis of the efflux pump component OprN

Xenon for tunnelling analysis of the efflux pump component OprN

... Tripartite efflux pumps are among the main actors responsible for antibiotics resistance in Gram-negative ...MexEF efflux pump from Pseudomonas ...passive efflux mecha- nism of ...

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Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

... MmpS5/MmpL5 efflux pump and accounting for high resistance levels toward various TAC analogs ( Halloum et ...MmpS5/MmpL5 efflux pump machinery ( Halloum et ...

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MexEF-OprN efflux pump exports the Pseudomonas quinolone signal (PQS) precursor HHQ (4-hydroxy-2-heptylquinoline)

MexEF-OprN efflux pump exports the Pseudomonas quinolone signal (PQS) precursor HHQ (4-hydroxy-2-heptylquinoline)

... multidrug efflux pumps conferring adaptive resistance to ...these efflux pumps also influences quorum ...MexEF-OprN efflux pump modulates quorum sensing through secretion of a signalling ...

12

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa

<em>In vitro</em> Investigation of the MexAB Efflux Pump From <em>Pseudomonas aeruginosa</em>

... membrane, efflux transporters are organized as tripartite systems where MexB, the efflux pump located in the inner membrane, works in conjunction with MexA, a periplasmic protein, and OprM, an outer ...

6

The overexpression of the efflux pump Tpo1 leads to the bleomycin resistance in Saccharomyces cerevisiae

The overexpression of the efflux pump Tpo1 leads to the bleomycin resistance in Saccharomyces cerevisiae

... Based on this finding, we used IMP2 as a tool to make double mutants. Our data revealed that when TPO1, TPO2 and QDR3 are mutated in combination with IMP2, cells become extremely sensitive to bleomycin and polyamines, as ...

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Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

... 3. Nagano K, Nikaido H. 2009. Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli. Proc Natl Acad Sci U S A 106:5854-5858. 4. Dewitt SK, Adelberg EA. 1962. The Occurrence of a ...

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Quantum dot probes for the quantitative study of drug transport by the MacAB TolC efflux pump in lipid scaffolds

Quantum dot probes for the quantitative study of drug transport by the MacAB TolC efflux pump in lipid scaffolds

... of efflux pumps that belong to the Resistance-Nodulation-Cell-Division (RND) superfamily, with, as most studied members AcrAB-TolC tripartite system from ...tripartite efflux pump from Escherichia ...

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Sorafenib Overcomes Irinotecan Resistance in Colorectal Cancer by Inhibiting the ABCG2 Drug-Efflux Pump

Sorafenib Overcomes Irinotecan Resistance in Colorectal Cancer by Inhibiting the ABCG2 Drug-Efflux Pump

... Abstract Despite recent advances in the treatment of colorectal cancer (CRC), tumor resistance is a frequent cause of chemotherapy failure. Therefore, new treatment options are needed to improve survival of patients with ...

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Functional investigation of the efflux pump MexA–MexB-OprM of Pseudomonas aeruginosa

Functional investigation of the efflux pump MexA–MexB-OprM of Pseudomonas aeruginosa

... of efflux pumps from resistance nodulation division family As developed in the previous paragraph, efflux pumps from the RND family consist of three main ...since efflux pump work as a ...

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In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa

In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa

... is assembled, MexB might adopt a conformation that allows the recruitment of substrate at a lower concentration than in the absence of OprM. The first in vitro reconstitution of a tripartite efflux pump is presented ...

6

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria

... a pump inhibitor with a potential of targeting efflux systems in a wide panel of Gram-positive human pathogenic ...know pump substrates revealed at least two active compounds; chlorogenic acid with ...

13

Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.: Sorafenib inhibits ABCG2 and overcome irinotecan resistance.

Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.: Sorafenib inhibits ABCG2 and overcome irinotecan resistance.

... These results indicate that, in SN-38 resistant HCT116-SN50 xenografts, the combination of sorafenib plus irinotecan inhibits tumor cell proliferation and angiogenesi[r] ...

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Leakage flow simulation in a specific pump model

Leakage flow simulation in a specific pump model

... [11] Eisele K., Zhang Z., Casey M. V., Gülich J., Schachenmann A. 1997 Flow analysis in a Pump Diffuser Part 1 : LDA and PTV Measurements of the Unsteady FlowTransactions of ASME, Journal of Fluids EngineeringVol. ...

11

Polarization-resolved pump-probe spectroscopy with high harmonics

Polarization-resolved pump-probe spectroscopy with high harmonics

... 7. Pump-probe scans for H21 in a 50 /50 mixture of argon and nitrogen, around the half revival of N 2 ...the pump–probe delay would allow an additional contrast ...

12

Parametric gain shaping from a structured pump pulse

Parametric gain shaping from a structured pump pulse

... D. Bigourd, C. Fourcade-Dutin and H. Maillotte are with the Institut FEMTO- ST, Département d’Optique, UMR 6174 CNRS-Université Bourgogne Copyright (c) 2018 IEEE representative of the spectral gain) is recorded with a ...

5

Innovative linear pulsatile pump for heart assistance circulatory

Innovative linear pulsatile pump for heart assistance circulatory

... The present contribution deals with the development of a magneto-active pump devoted to ventricular assist device. The actuator studied is a cylindrical linear switched reluctance motor equipped with a ...

7

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy

... ‘peristaltic pump mechanism’ and the ‘functionally rotating ordered multidrug binding change mechanism’ 27,31 are very promising but not totally satisfactory for the definition of suitable physico- chemical ...

8

NRC wave pump tests for numerical model development

NRC wave pump tests for numerical model development

... damage pump internal parts and cause vibrations. Video of the pump cylinder was recorded for most of the ...the pump cylinder in tests with a period less than 4 ...the pump drive end internals ...

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Innovative linear pulsatile pump for heart assistance circulatory

Innovative linear pulsatile pump for heart assistance circulatory

... 1 I NTRODUCTION Heart failure is one of the most common diseases in developed countries. Because the number of donor heart is limited, patients suffering from end-stage heart failure require mechanical circulatory ...

8

Computer simulation of ground coupled heat pump systems

Computer simulation of ground coupled heat pump systems

... L’accès à ce site Web et l’utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D’UTILISER CE SITE WEB. NRC Publicat[r] ...

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