dopamine transporter
The Story of the Dopamine Transporter PET Tracer LBT-999: From Conception to Clinical Use
... membrane dopamine transporter (DAT) is involved in a number of brain disorders and its exploration by positron emission tomography (PET) imaging is highly relevant for the early and differential diagnosis, ...
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Polymorphism of the dopamine transporter type 1 gene modifies the treatment response in Parkinson's disease.
... The dopamine transporter type 1, now known as solute carrier family 6 (neurotransmitter transporter), member 3 (SLC6A3) is the most powerful determinant of dopamine neurotransmission and might ...
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Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice.
... the dopamine transporter (DAT-/-) are characterized by high extracellular dopamine levels and spontaneous ...a dopamine-mediated effect. These results emphasize the role of dopamine ...
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Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter.
... words: dopamine transporter, d-amphetamine, locomotor activity, stereotypy, behavioral sensitization, fluoxetine, autoradiography INTRODUCTION The dopamine transporter (DAT) is located on the ...
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Increased rewarding properties of morphine in dopamine-transporter knockout mice.
... Introduction Morphine and related opioids increase nigrostriatal and mesolimbic dopamine (DA) turnover, metabolism and release (Di Chiara & Imperato, 1988; Di Chiara & North, 1992). In the ventral ...
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Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys.
... of dopamine agonists (ropinirole or pramipexole) ...of dopamine agonists on DAT binding may also be involved and cannot be inferred from the present ...
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Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum.
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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Altered neurotensin mrna expression in mice lacking the dopamine transporter.
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson's disease
... and dopamine transporter single-photon emission tomography were performed to assess nigrostriatal levels of neuromelanin, iron, and ...striatal dopamine and iron, and nigral neuromelanin and iron; in ...
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Unilateral Lesion of Dopamine Neurons Induces Grooming Asymmetry in the Mouse
... 6-OHDA lesion, in which the total amount of grooming was not affected [ 13 ]. This discrep- ancy could be explained considering the different techniques for inducing grooming in this study and ours. After bilateral ...
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Dynamical ventral tegmental area circuit mechanisms of alcohol‐dependent dopamine release
... range, in order to have a heterogeneous excitability (e.g. firing rate ranges from 0.5 to 3Hz for partially synchronous Glu inputs at 4Hz and no EtOH)). Overall dopamine release was model as a sum of all the ...
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DARPP-32 is a robust integrator of dopamine and glutamate signals.
... Nishi and colleagues [15] showed that in the case of dopamine stimulation, i.e., cAMP increase, D34 and D75 were mutually antagonistic. However, the same authors showed afterward [16] that in the case of a ...
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Activation of D1 Dopamine Receptors Induces Emergence from Isoflurane General Anesthesia
... There are five types of G protein–coupled dopamine receptors, broadly divided into two classes: D1-like and D2-like. 29 The D1 subfamily includes the D1 and D5 receptors, which are postsynaptic and mediate ...
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Modélisation computationnelle du rôle de la dopamine dans les boucles cortico-striatales dans l'apprentissage et la régulation de la sélection de l'action
... la dopamine avec une augmentation du niveau dopaminergique favorisant l’exploration et une diminution, ...la dopamine dans le modèle rBCBG est différente de celles des deux autres ...la dopamine ...
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LC–MS/MS-based quantification of efflux transporter proteins at the BBB
... a b s t r a c t Targeted protein quantification using tandem mass spectrometry coupled to high performance chro- matography (LC–MS/MS) has been used to quantify proteins involved in the absorption, distribution, ...
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Regulation of photosynthesis by a potassium transporter in the diatom Phaeodactylum tricornutum
... (2006) ‘In diatoms, the transthylakoid proton gradient regulates the photoprotective non-photochemical fluorescence quenching beyond its control on the xanthophyll cycle’, Plant and[r] ...
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Characterization of the membrane transporter OATP1A2 activity towards different classes of drugs
... 167 As discussed earlier, there are situations where a DDI has been observed in vitro as well as in vivo but the effect observed is not necessarily attributed to the transporter studied. For example, the ...
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Dopamine et dégénérescence des neurones striataux dans la maladie de Huntington : vers l'identification de nouvelles cibles thérapeutiques
... DA transporter knockout mice, spontaneous striatal death accom- panied by behavioral alterations that resemble HD are observed during aging specifically ...
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PSD-95 expression controls l-DOPA dyskinesia through dopamine D1 receptor trafficking
... of dopamine replacement therapy for Parkin- son’s disease, is associated with an alteration in dopamine D1 receptor (D1R) and glutamate receptor interac- ...
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Molecular characterization of a new urea transporter in the human kidney
... Recently, immunofluorescence analysis of human kidney sections demonstrated that the Kidd/urea transporter protein HUT11 is constitutively expressed by endothelial cells of v[r] ...
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