Diffuse large B cells lymphoma
Gene expression-based risk score in diffuse large B-cell lymphoma.
... tumor cells of patients within high risk GERS group (supplementary Figure S1 and supplementary Tables S1, S2 and ...develop lymphoma after a long latency[33]. In non-Hodgkin lymphoma, MCL1 expression ...
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Induction of autophagy and autophagy-dependent apoptosis in diffuse large B-cell lymphoma by a new antimalarial artemisinin derivative, SM1044
... Abstract Diffuse large B- cell lymphoma (DLBCL) is the most common form of non- Hodgkin’s ...DLBCL cells, but also suggest that SM1044 is a promising therapeutic molecule for the ...
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CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma
... Discussion Previous reports have described limitations in using short peptide sequences from tumor-associated antigens to elicit long-lasting CTL responses to the target molecule. Repeated boosting with peptides may be ...
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Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma.
... to cells, because they block DNA helix opening due to chemical reactions involving bases of opposed strands, result- ing in irreversible covalent ...cancer cells exposed to DNA damaging agents, NER play a ...
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Sp17 Protein Expression and Major Histocompatibility Class I and II Epitope Presentation in Diffuse Large B Cell Lymphoma Patients
... lymphoid cells, including B- and T-lymphoid cell lines, and on the surface of primary cells isolated from two patients having B-lymphoid tumours ...neoplastic cells, but not in normal ...
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Role of ETS1 in the transcriptional network of diffuse large B cell lymphoma of the activated B cell-like type
... hematopoietic cells to extracellular matrix, including an inhibitory activity on MAPK signaling [ 47 ...tumor cells’ ...GC B cells and lymphoma cell lines in which it desensitizes ...
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MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation.
... 1/50; A.H. Banham, Oxford, United Kingdom) were performed using 3- m sections either from either full slides or from tissue μ microarrays (TMAs) containing two or three representative 0.6-mm cores of routinely FFPE ...
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An alternative way to look at diffuse large B-cell lymphoma : the impact of frequent engagement of ReIB NF-κB subunit on cell survival and patient outcome
... cancer cells, at least partially via the induction of the MnSOD gene [ 56 , 57 ...cancer cells reduced cyclin D1 and c-myc expression, slower proliferation, and repressed transformed phenotype [ 59 ...these ...
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Soluble programmed death-ligand 1 as a prognostic biomarker for overall survival in patients with diffuse large B-cell lymphoma: a replication study and combined analysis of 508 patients
... consistent with a recent report on R-CHOP treated Korean DLBCL patients that used the same PD- L1 antibody, 11 but is not universal. 12 We reported that DLBCL patients expressing PD-L1 on non- malignant cells ...
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The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.
... Two other genes (APOBEC3G, RAB33A) showed differential effects in CHOP and R- CHOP patients and demonstrated a significant correlation with OS in R-CHOP patients independently of the COO classification. APOBEC3G encodes ...
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Pro-apoptotic effect of doxycycline and hydroxychloroquine on B-cell lymphoma induced by C. burnetii
... tumor cells by activating caspase-3 and ...cancer cells, and in melanoma, oral squamous cell carcinoma and in two- thirds of MALT lymphoma associated with Chlamydia psittaci ...of B-cell ...
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Mesenchymal stromal cells orchestrate follicular lymphoma cell niche through the CCL2-dependent recruitment and polarization of monocytes.: CCL2 AND FOLLICULAR LYMPHOMA CELL NICHE
... pos cells in patients treated with chemotherapy 27,43 ...cell/malignant B cell ...neoplastic B-cell remain unknown even if their production of B cell-activating factor of the TNF family (BAFF) ...
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Evidence for IL-35 Expression in Diffuse Large B-Cell Lymphoma and Impact on the Patient's Prognosis
... COS7 cells), IL-35 (non-covalently linked heterodimer produced in HEK293 cells, Peprotech), IL-35-Fc (fusion protein produced in HEK293 cells, consisting of EBI3 linked to p35 fused to the Fc portion ...
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Diffuse large B-cell lymphoma of Waldeyer's ring has distinc clinicopathologic features: a GELA study.
... WR DLBCLs frequently exhibit a partially nodular growth pattern Although all cases ful filled the DLBCL diagnostic criteria and the majority of the cases (144 cases, 77%) exhibited a purely diffuse distribution of ...
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Cytolytic T-cell response to the PASD1 cancer testis antigenin patients with diffuse large B-cell lymphoma
... rich B-cell ...T cells varied between patients, ranging from 1:600 (0Æ17%) PBMCs in Patient 1 to 1:2000 (0Æ05%) in Patient ...rich B-cell lymphoma (n = ...
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Diffuse large B-cell lymphoma of Waldeyer's ring has distinct clinicopathologic features: a GELA study.
... WR DLBCLs frequently exhibit a partially nodular growth pattern Although all cases ful filled the DLBCL diagnostic criteria and the majority of the cases (144 cases, 77%) exhibited a purely diffuse distribution of ...
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CD4 T-Helper Responses to the Anaplastic Lymphoma Kinase (ALK) Protein in Patients with ALK-Positive Anaplastic Large-Cell Lymphoma
... culture, cells were incubated for 18 h in complete RPMI 1640/FCS at 37 jC in 5% CO 2 with ALK1 278–301 , ALK2 233–256 , ALK3 411–434 , HIV 121–140 , or PHA, or medium ...
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Long non-coding RNAs as molecular signatures for canine B-Cell lymphoma characterization
... in B-cell lymphoma, comprehensive characterization of the transcriptome, prognostic role, and functional contribution of lncRNAs in distinct B-cell subtypes are ...to B- cells has been ...
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Increased activation of PI3 kinase-δ predisposes to B cell lymphoma.
... (mainly B lymphoma) is the main complication, and is associated with a much worse ...fact, B cell lymphoma can even be the revealing symptom in ...
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B Cells Promote Pancreatic Tumorigenesis
... immune cells (e.g., CD8 T cells and macrophages) in the tumor microenvironment and promoting pancreatic cancer cell ...of B cell infiltration into the tumor by blocking chemokine CXCL13, inhibition ...
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