Diffuse large B-cell lymphomas
Diffuse large B-cell lymphomas of the waldeyer's ring frequently have a germinal center-like phenotype: a clinico-pathological study of 209 patients from the groupe d'étude des lymphomes de l'adulte (GELA).
... .. Diffuse large B-cell lymphomas (DLBCLs) are markedly heterogeneous, and there is increasing evidence that the biological features of these tumors vary according to the primary site ...
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Diffuse Large B-cell Lymphomas of the waldeyer's ring frequently have a germinal center-like phenotype: a clinico-pathological study of 209 patients from the groupe d'étude des lymphomes de l'adulte (GELA).
... Among large biopsy specimens (n=79), 18% had a prominent nodular pattern consistent with transformed follicular lymphomas, 35% had a minor nodular component (<50%) interpre[r] ...
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Non-invasive monitoring of diffuse large B-cell lymphoma by cell-free DNA high-throughput targeted sequencing: analysis of a prospective cohort
... biopsy, cell-free DNA (cfDNA) can provide information regarding basal tumoral genetic patterns and changes upon ...30 diffuse large B-cell lymphomas (DLBCL), we determined the ...
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Soluble programmed death-ligand 1 as a prognostic biomarker for overall survival in patients with diffuse large B-cell lymphoma: a replication study and combined analysis of 508 patients
... in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor ...programmed cell death 1 and programmed cell death ligand 1 expression in the tumour ...
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MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation.
... with diffuse large B-cell lymphoma treated with R-CHOP: a GELA study ...in diffuse large B-cell lymphomas treated within randomized trials of the German ...
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Gene expression-based risk score in diffuse large B-cell lymphoma.
... Tan B, Goldschmidt N, Iqbal J, Vose J, Bast M, Fu K, Weisenburger DD, Greiner TC, Armitage JO, Kyle A, May L, Gascoyne RD, Connors JM, Troen G, Holte H, Kvaloy S, Dierickx D, Verhoef G, Delabie J, Smeland EB, ...
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Diffuse large B-cell lymphoma of Waldeyer's ring has distinct clinicopathologic features: a GELA study.
... Our analysis has shed light on peculiar pathologic features of WR DLBCLs, somewhat different from those usually reported for DLBCLs, NOS. First, we show that WR DLBCLs comprise a majority of tumors (60%) with a GCB-like ...
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Evidence for IL-35 Expression in Diffuse Large B-Cell Lymphoma and Impact on the Patient's Prognosis
... DISCUSSION In previous studies, we had shown that EBI3 is expressed by tumor cells in various types of B- or T-cell lymphomas, especially in DLBCL, in most cases in the absence of p28, its binding ...
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Primary bone diffuse large B-cell lymphoma: a retrospective evaluation on 76 cases from French institutional and LYSA studies
... Several retrospective studies reported PB lympho- mas separately and suggested that these topographic variants may have a seemingly favorable prognostic particularly when combining chemotherapy and radi- ation therapy ( ...
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Diffuse large B-cell lymphoma of Waldeyer's ring has distinc clinicopathologic features: a GELA study.
... Our analysis has shed light on peculiar pathologic features of WR DLBCLs, somewhat different from those usually reported for DLBCLs, NOS. First, we show that WR DLBCLs comprise a majority of tumors (60%) with a GCB-like ...
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Regulatory myeloid cells: an underexplored continent in B-cell lymphomas
... In B-cell lymphomas, the myeloid compartment contributes to prognosis Lymphomas constitute a large group of cancer arising from lymphoid or extra- nodal tissues ...are ...
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Cytolytic T-cell response to the PASD1 cancer testis antigenin patients with diffuse large B-cell lymphoma
... Discussion We previously identified PASD1 as a novel DLBCL-associated CTA using the SEREX technique (Liggins et al, 2004a,b). This approach, which relies upon the presence of a co-ordinated cellular and humoral ...
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The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab.
... of cell of origin signature in R-CHOP patients Wright et al established a predictor for Germinal Center (GC) and Activated B-Cell (ABC) classification of DLBCL lymphomas, based on the ...
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Role of ETS1 in the transcriptional network of diffuse large B cell lymphoma of the activated B cell-like type
... GC B cells and lymphoma cell lines in which it desensitizes cells to chemoattractant, localizing cells to the lymph node [ 29 ...and B cells, with a still-unclear ...in lymphomas [ 49 ...and ...
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A longitudinal study of non-medical determinants of adherence to R-CHOP therapy for diffuse large B-cell lymphoma: implication for survival
... The impact of RDI on outcome in lymphomas treated with CHOP and related regimens, has been investigated before the introduction of rituximab [9-11,15,16]. Since the introduction of rituximab at the end of the 90s, ...
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Subcutaneous Rituximab-MiniCHOP compared with subcutaneous Rituximab-MiniCHOP plus Lenalidomide in diffuse large B-Cell lymphoma for patients age 80 years or older.
... frequency of the two main molecular –defined subtypes, namely, germinal center B-cell –like (GCB) and activated B-cell –like (ABC) subtypes, differs according to patient age. Additionally, an ...
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Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies.
... Non-Hodgkin Lymphomas Non-Hodgkin lymphomas are B-cell malignancies that are primarily located in lymph ...from B-cell precursors ( 69 ...Aggressive lymphomas are rapidly ...
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en fr Role of Orai1 and STIM1 in B-cell non-Hodgkin lymphomas, establishment of a new 3D cell culture model. Rôle des protéines Orai1 et STIM1 dans les lymphomes B non-Hodgkiniens, établissement d'un modèle d'étude en 3D.
... Méthodes de biologie cellulaire B. Protocole Les tests de migration en chambre de Boyden sont effectués en plaques 96 puits HTS transwell (Corning LifeScience). L’insert est constitué d’une membrane en ...
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Treatment of mantle cell lymphomas: recommendations of the Belgian Hematological Society
... non-Hodgkin's lymphomas. Mantle cell lymphoma generally affects patients over 60 ...mantle cell lymphoma. The cell-proliferation marker Ki-67, the Mantle Cell Lymphoma International ...
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CD30-positive peripheral T-cell lymphomas share molecular and phenotypic features
... nuclear translocation, MAP kinase activation (ERK, JNK and p38), tran- scription and cytokine release. CD69 and ICOS, upregulated follow- ing TCR engagement, act as co- stimulatory molecules. Syk is a ZAP-70 homolog ...
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