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creatine kinase

The creatine kinase system and pleiotropic effects of creatine.

The creatine kinase system and pleiotropic effects of creatine.

... Introduction Creatine (Cr) has emerged as a safe nutritional supplement not only to increase muscle mass and performance, prevent disease-induced muscle atrophy and improve rehabilita- tion, but also to strengthen ...

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Ratio of high-sensitivity troponin to creatine kinase-MB in takotsubo syndrome.

Ratio of high-sensitivity troponin to creatine kinase-MB in takotsubo syndrome.

... and creatine kinase than STEMI [11,12] ...in creatine kinase [7,13] , more speci fically its myocardial fraction (CKMB), is smaller in comparison to the elevation in troponin than in myocardial ...

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Genetic association study of plasma creatine kinase levels in the Montreal Heart Institute Hospital Cohort

Genetic association study of plasma creatine kinase levels in the Montreal Heart Institute Hospital Cohort

... ii 2 ABSTRACT Statins (HMG-CoA reductase inhibitors) have been shown to reduce LDL-cholesterol and are undoubtedly the mainstay in the treatment of hyperlipidemia. Approximately 10 percent of statin users suffer from ...

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Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML

Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML

... Next, we performed single-sample Gene Set Enrichment Analysis (ssGSEA) in two large human primary patient AML gene expression datasets Wouters et al. (n=526, GSE14468) and Tomasson et al. (n=304, GSE10358). In both ...

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The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

... the creatine kinase pathway. Creatine is one of the end products of the arginine pathway, which is altered upon EVI1 ...the creatine kinase pathway and suggests that EVI1-positive ...

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View of Diagnostic Utility of Creatine Kinase in Patients Presenting to the Emergency Department with Chest Pain

View of Diagnostic Utility of Creatine Kinase in Patients Presenting to the Emergency Department with Chest Pain

... (creatine kinase) is also released into the blood stream as myocardial cells become infarcted and is one of the first cardiac biomarkers available in history to assess for ...

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Systems Level Regulation of Cardiac Energy Fluxes Via Metabolic Cycles: Role of Creatine, Phosphotransfer Pathways, and AMPK Signaling

Systems Level Regulation of Cardiac Energy Fluxes Via Metabolic Cycles: Role of Creatine, Phosphotransfer Pathways, and AMPK Signaling

... by creatine in permeabilized ...pyruvate kinase (PK) continuously trap extra-mitochondrial ADP to regenerate ...mitochondrial creatine kinase (MtCK) that controls respiration through ...

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A generic HTS assay for kinase screening: Validation for the isolation of an engineered malate kinase

A generic HTS assay for kinase screening: Validation for the isolation of an engineered malate kinase

... malate kinase, malate semialdehyde dehy- drogenase and malate semialdehyde reductase was envisaged as a feasible enzyme cascade for the three-step conversion of (L)-malate into ...Malate kinase (MK) ...

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Identification de nouveaux substrats de la voie Ras-MAP Kinase

Identification de nouveaux substrats de la voie Ras-MAP Kinase

... synthase kinase-3 (GSK3), dont le rôle consiste notamment à phosphoryler la beta-caténine afin de cibler la protéine pour dégradation par le protéasome ...MAP Kinase est suffisante pour promouvoir une ...

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Kinase C substrates and synaptic plasticity in Aplysia

Kinase C substrates and synaptic plasticity in Aplysia

... Understanding how memories are stored and retrieved has been the goal of work in several scientific disciplines, including neuroscience, neuropsychology, psychology, and cognitive scienc[r] ...

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Aurora B kinase, an immobile passenger!

Aurora B kinase, an immobile passenger!

... More data are necessary for elucidating the role of the CPC, its organisation within the centromere and for analysing dynamically Aurora B kinase substrates. In the near future, the definition of the interfaces ...

3

AMP-activated protein kinase and autophagy.

AMP-activated protein kinase and autophagy.

... autophagy for eukaryotic elongation factor 2-kinase (eEF-2 kinase), 17 which is known to be activated by AMPK. 18 Interestingly, in many cases where AMPK can be expected to be activated autophagy is known ...

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Protein kinase C and human uterine contractility.

Protein kinase C and human uterine contractility.

... It seems to be less obvious whether PRKC plays a role in the kinase cascade involved in the myometrial contractile process during human pregnancy. We have attempted to individualize the PRKC isoform able to ...

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La protéine kinase CK2, une enzyme qui cultive la différence

La protéine kinase CK2, une enzyme qui cultive la différence

... protéine kinase « à part ...la kinase dans tous les cancers peut pour l’instant n’être qu’une coïncidence ; il faut toutefois noter que le caractère oncogénique de la CK2 a été établi dans plusieurs ...

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Impact de la localisation de la CaM Kinase II sur la plasticité synaptique

Impact de la localisation de la CaM Kinase II sur la plasticité synaptique

... Le point de départ pour générer de la potentialisation en culture a été le papier Lu et al., 2001 dans lequel est démontré qu'une simple stimulation de 3 minutes avec une solution sans[r] ...

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Rôle de la protéine tyrosine kinase Fer dans le cancer de la prostate

Rôle de la protéine tyrosine kinase Fer dans le cancer de la prostate

... Une autre observation importante concerne les niveaux des complexes Fer/actine. Nous avons montré que l’activité de Fer n’affecte pas les complexes Fer/actine alors que les niveaux de ph[r] ...

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Modélisation et analyse de l'interactome de la kinase humaine Aurora A

Modélisation et analyse de l'interactome de la kinase humaine Aurora A

... Résumé La kinase Aurora A est une protéine essentielle au cycle cellulaire et plus particulièrement lors de la mitose. En effet, Aurora A est nécessaire dès l’entrée en mitose et régule sa progression. Elle joue ...

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Le récepteur tyrosine kinase c-Kit - Une nouvelle cible pour les antalgiques ?

Le récepteur tyrosine kinase c-Kit - Une nouvelle cible pour les antalgiques ?

... (PKCγ) et de la phospholipase C epsilon (PLCε) sensibilisant de manière mineure TRPV1 par phosphorylation des résidus sérines 502 et 801 [6, 13, 19] . Enfin, PI3K a aussi été impliquée dans la sensibilisation par ...

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