combination antiretroviral therapy
![[Mortality rate of HIV-infected adults on long term combination antiretroviral therapy.]](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
[Mortality rate of HIV-infected adults on long term combination antiretroviral therapy.]
... Lancet 2003;362:679-86. 4. Lewden C, Chêne G, Morlat P, Raffi F, Dupon M, Dellamonica P, Pellegrin JL, Katlama C, Dabis F, Leport C, the ANRS CO8 APROCO-COPILOTE Study Group, the ANRS CO3 Aquitaine Study Group. ...
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HIV-infected adults with a CD4 cell count greater than 500 cells/mm3 on long-term combination antiretroviral therapy reach same mortality rates as the general population.
... Mortality rates and standardized mortality ratio (SMR) in HIV-infected adults, ANRS CO8 APROCO-COPILOTE and ANRS CO3 AQUITAINE cohorts, 1997-2005, according to cumulated time spent with[r] ...
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Mortality according to CD4 count at start of combination antiretroviral therapy among HIV positive patients followed for up to 15 years after start of treatment: collaborative cohort study
... low baseline CD4 count, especially immunological non-responders, while others gradually achieve immunological recovery. The suggestion of a lower risk amongst those who started ART with very low compared with ...
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Cost‑Effectiveness Analysis of Lopinavir/Ritonavir Monotherapy Versus Standard Combination Antiretroviral Therapy in HIV‑1 Infected Patients with Viral Suppression in France (ANRS 140 DREAM)
... mono- therapy is heavily dependent on the evolution of ARV prices, we used an original method—the cost-effectiveness price- threshold (CEPT) analysis—to provide additional informa- tion on the strategy that would ...
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Incidence and risk factors of HIV-related non-Hodgkin's lymphoma in the era of combination antiretroviral therapy: a European multicohort study.
... The CD4 cell count at which cART should be initiated is a central but unresolved issue in the care of HIV-1 infected patients. The results of our study are relevant to this debate: the strong relationship between ...
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Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy
... started combination antiretroviral therapy (ART) soon after it became widely available in Europe and North America in 1996 have been treated for up to 20 years[ 1 ...
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Increased non-AIDS mortality among persons with AIDS-defining events after antiretroviral therapy initiation and for the Antiretroviral Therapy Cohort Collaboration (ART-CC) investigators
... Introduction: HIV-1 infection leads to chronic inflammation and to an increased risk of non-AIDS mortality. Our objective was to determine whether AIDS-defining events (ADEs) were associated with increased overall and ...
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Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virological failure in Rwanda.
... in combination with lamivudine and boosted lopinavir or atazanavir as the choice second-line regimen is viable despite the large number of individuals with a large number of HIV drug ...
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Patient- and population-level health consequences of discontinuing antiretroviral therapy in settings with inadequate HIV treatment availability.
... more antiretroviral regimens, though the impact is mitigated if more regimens are ...about antiretroviral discontinuation after treatment failure, context-specific analyses that rely on sound, local data ...
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Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants.
... A patient was defined as lost-to-follow-up if his last contact with the care centre was > 3 months (patients who ever started ART) or > 6 months (patients who never started ART)[r] ...
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Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities
... certain antiretroviral drugs (particularly some nucleoside reverse-transcriptase inhibitors (NRTIs) and protease inhibitors (PIs)), antiretroviral therapy (ART)-induced lipodystrophy, and classical ...
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Long-term immunologic response to antiretroviral therapy in low-income countries: a collaborative analysis of prospective studies.
... Note that time on treatment was in years from start of treatment, but adding one year as to allow flexible and accurate modelling of CD4 response close to the start of treatment. Thus, [r] ...
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Impact of Highly Active Antiretroviral Therapy on Chronic Hepatitis B Serological Markers among Senegalese HIV Co-infected Children
... In Senegal, data are scarce in the pediatric HIV-HBV co-infected children. 1.2. Objectives of the Study The objective of this study was to investigate the prevalence of HBV infection in children with HIV infection, and ...
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Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings.
... Eligibility criteria and definitions For this analysis, we selected from the IeDEA database all HIV-1 infected naïve adults (16 years or older) with gen- der and date of ART initiation known, treated with a first–line ...
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Antiviral efficacy and resistance in patients on antiretroviral therapy in Kigali, Rwanda: the real-life situation in 2002.
... to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing ...
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View of Immune reconstitution inflammatory syndrome in Human Immunodeficiency Virus-infected patients treated with antiretroviral therapy
... Early antiretroviral therapy (ART) for Human Immunodeficiency Virus (HIV) infected people has led to a decrease in the risk of mortality and in the occurrence of opportunistic infections ...
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Early antiretroviral therapy of HIV-infected infants in resource-limited countries: possible, feasible, effective and challenging.
... The paper from Prendergast and colleagues published in this issue of AIDS adds to the evidence that excellent adherence and virologic response can be achieved in HIV-infected children receiving cART in sub-Saharan Africa ...
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Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire.
... 8 Dabis F, Bequet L, Ekouevi D, Viho I, Sakarovitch C, Becquet R, et al. Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent peripartum HIV transmission. AIDS 2005;19(3):309-18. 9. Tonwe-Gold ...
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Sustained HBs seroconversion during lamivudine and adefovir dipivoxil combination therapy for lamivudine failure
... In the Lyon Liver Department, we followed a cohort of 60 patients that received adefovir dipivoxil in a compassionate use program from the AFSSAPS (French Drug Agency) for lamivudine resistance. All patients received ADV ...
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An archaeosome-adjuvanted vaccine and checkpoint inhibitor therapy combination significantly enhances protection from murine melanoma
... inhibitor therapy has even been approved for use as a monotherapy, its mode of action being to ‘remove the brakes’ on a patient’s existing tumor-specific CD8 + T ...
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